Organization profile
Organization profile
The Advanced Light Microscopy Core at Penn State College of Medicine provides consultation and training in ultra-high-resolution imaging of cells and tissues in fixed or live states. We also provide expertise in quantitative image analysis and consultations on microscopy-related research projects.
RRID:SCR_022526
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Collaborations and top research areas from the last five years
Research output
- 222 Citations
- 9 h-index
- 18 Article
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Phosphorylation of the selective autophagy receptor TAX1BP1 by TBK1 and IKBKE/IKKi promotes ATG8-family protein-dependent clearance of MAVS aggregates
White, J., Choi, Y. B., Zhang, J., Vo, M. T., He, C., Shaikh, K. & Harhaj, E. W., 2025, In: Autophagy. 21, 1, p. 160-177 18 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations -
Activity of DNA polymerase κ across the genome in human fibroblasts
Torres, M. C., Rebok, A., Sun, D. & Spratt, T. E., Jul 9 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 28, e2403130121.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Comparative analysis of retroviral Gag-host cell interactions: focus on the nuclear interactome
Lambert, G. S., Rice, B. L., Maldonado, R. J. K., Chang, J. & Parent, L. J., Dec 2024, In: Retrovirology. 21, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
ER stress elicits non-canonical CASP8 (caspase 8) activation on autophagosomal membranes to induce apoptosis
Hattori, T., Fundora, K. A., Hamamoto, K., Opozda, D. M., Liang, X., Liu, X., Zhang, J., Uzun, Y., Takahashi, Y. & Wang, H. G., 2024, In: Autophagy. 20, 2, p. 349-364 16 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Link opens in a new tab Scopus citations -
Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure
Ye, Y., Liang, X., Wang, G., Bewley, M. C., Hamamoto, K., Liu, X., Flanagan, J., Wang, H.-G., Takahashi, Y. & Tian, F., Dec 2024, In: Communications Biology. 7, 1, 334.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Scopus citations -
LC3-associated phagocytosis of neutrophils triggers tumor ferroptotic cell death in glioblastoma
Lu, T., Yee, P. P., Chih, S. Y., Tang, M., Chen, H., Aregawi, D. G., Glantz, M. J., Zacharia, B. E., Wang, H.-G. & Li, W., Jul 1 2024, In: EMBO Journal. 43, 13, p. 2582-2605 24 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Link opens in a new tab Scopus citations -
PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis
Khatib, J. B., Dhoonmoon, A., Moldovan, G. L. & Nicolae, C. M., Dec 2024, In: Nature communications. 15, 1, 6197.Research output: Contribution to journal › Article › peer-review
Open Access13 Link opens in a new tab Scopus citations -
Phosphorylation of aryl hydrocarbon receptor interacting protein by TBK1 negatively regulates IRF7 and the type I interferon response
Kazzaz, S. A., Shaikh, K. A., White, J., Zhou, Q., Powell, W. H. & Harhaj, E. W., Jan 2024, In: Journal of Biological Chemistry. 300, 1, 105525.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
The effects of submicron-textured surface topography on antibiotic efficacy against biofilms
Khursheed, A., Xu, L. & Siedlecki, C. A., Jul 2024, In: Journal of Biomedical Materials Research - Part B Applied Biomaterials. 112, 7, e35436.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation
Saha, K., Subramenium Ganapathy, A., Wang, A., Arumugam, P., Michael Morris, N., Harris, L., Yochum, G., Koltun, W., Perdew, G. H., Nighot, M., Ma, T. & Nighot, P., Dec 2023, In: Mucosal Immunology. 16, 6, p. 826-842 17 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations
Equipment
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COM-ALM-Deltavision Elite Inverted Widefield Microscope
Advanced Light Microscopy (ALM) Biomedical Core FacilityEquipment/facility: Equipment
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COM-ALM-IMARIS, VOLOCITY and HUYGENS Workstations
Advanced Light Microscopy (ALM) Biomedical Core FacilityEquipment/facility: Equipment
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COM-ALM-Leica SP8 inverted confocal microscope with STED 3X
Advanced Light Microscopy (ALM) Biomedical Core FacilityEquipment/facility: Equipment
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COM-ALM-Miltenyi Ultramicroscope II Light Sheet Microscope
Advanced Light Microscopy (ALM) Biomedical Core FacilityEquipment/facility: Equipment
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COM-ALM-Nikon A1R Upright Multimodal Multiphoton Microscope
Advanced Light Microscopy (ALM) Biomedical Core FacilityEquipment/facility: Equipment