Research output per year
Research output per year
Organization profile
Organization profile
The Next-Generation Therapies research program at Penn State Cancer Institute discovers and characterizes novel agents and pathways; translates these discoveries through innovative, preclinical proof-of-principle studies; and provides more effective cancer therapies to patients.
Program members also collaborate with colleagues in biomedical engineering at Penn State University Park, as well as with Cancer Control research program members, regarding the role of exercise in treatment outcomes for cancer patients. Additional collaborations involve work with the Mechanisms of Carcinogenesis research program on the identification of genomic markers in metastatic melanoma as potential markers of response.
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Dive into the research topics where Cancer Institute, Next-Generation Therapies is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Dawit Aregawi, MD
- Department of Neurosurgery - Assistant Professor
- Penn State Cancer Institute
- Penn State Neuroscience Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Anilchandra Attaluri
- School of Science, Engineering & Technology (Harrisburg) - Associate Professor Of Mechanical Engineering
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
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James Broach, PhD
- Department of Biochemistry and Molecular Biology - Distinguished Professor and Chair
- Department of Otolaryngology - Head and Neck Surgery - Professor
- Institute for Personalized Medicine - Director
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Keith Cheng, MD, PhD
- Department of Pathology and Laboratory Medicine - Distinguished Professor
- Division of Experimental Pathology
- Department of Biochemistry and Molecular Biology - Distinguished Professor
- Department of Pharmacology - Distinguished Professor
- Penn State Cancer Institute
- Huck Institutes of the Life Sciences
- Institute for Computational and Data Sciences (ICDS)
- Cancer Institute, Next-Generation Therapies
Person: Academic
Research output
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18F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results from NRG-HN002
Subramaniam, R. M., DeMora, L., Yao, M., Yom, S. S., Gillison, M., Caudell, J. J., Waldron, J., Xia, P., Chung, C. H., Truong, M. T., Echevarria, M., Chan, J. W., JGeiger, E. L., Mell, L., Seaward, S., Thorstad, W. L., Beitler, J. J., Sultanem, K., Blakaj, D. & Le, Q. T., 2023, In: Journal of Nuclear Medicine. 64, 3, p. 362-367 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice
Zhu, X., Liu, Q., Patterson, A. D., Sharma, A. K., Amin, S. G., Cohen, S. M., Gonzalez, F. J. & Peters, J. M., Aug 2023, In: Metabolites. 13, 8, 936.Research output: Contribution to journal › Article › peer-review
Open Access -
A comparative study of in vitro dose–response estimation under extreme observations
Fang, X. & Zhou, S., 2023, (Accepted/In press) In: Biometrical Journal.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
Qian, F., Nettleford, S. K., Zhou, J., Arner, B. E., Hall, M. A., Sharma, A., Annageldiyev, C., Rossi, R. M., Tukaramrao, D. B., Sarkar, D., Hegde, S., Gandhi, U. H., Finch, E. R., Goodfield, L., Quickel, M. D., Claxton, D. F., Paulson, R. F. & Prabhu, K. S., Jul 25 2023, In: Cell Reports. 42, 7, 112794.Research output: Contribution to journal › Article › peer-review
Open Access -
Acute Low Dose Naltrexone Increases β-Endorphin and Promotes Neuronal Recovery Following Hypoxia-Ischemic Stroke in Type-2 Diabetic Mice
Kumari, R., Kareem, Z. Y. & McLaughlin, P. J., Sep 2023, In: Neurochemical Research. 48, 9, p. 2835-2846 12 p.Research output: Contribution to journal › Article › peer-review
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Adapting an Evidence-Based Exercise and Education Program for Older Breast Cancer Survivors for the REJOIN Trial
Bluethmann, S. M., Flores, E., Grotte, M., Heitzenrater, J., Truica, C. I., Olsen, N. J., Sciamanna, C. & Schmitz, K. H., Feb 2023, In: Journal of Aging and Physical Activity. 31, 1, p. 59-67 9 p.Research output: Contribution to journal › Article › peer-review
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Addiction III: From mouse to man
McLaughlin, P. J., West, E. A., Grigson, P. S. & Hobkirk, A. L., Feb 2023, In: Brain Research Bulletin. 193, p. 22-26 5 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Addressing metastatic individuals everyday: Rationale and design of the nurse AMIE for Amazon Echo Show trial among metastatic breast cancer patients
Gordon, B. R., Qiu, L., Doerksen, S. E., Kanski, B., Lorenzo, A., Truica, C. I., Vasekar, M., Wang, M., Winkels, R. M., Abdullah, S. & Schmitz, K. H., Apr 2023, In: Contemporary Clinical Trials Communications. 32, 101058.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Allosteric inactivation of an engineered optogenetic GTPase
Jain, A., Dokholyan, N. V. & Lee, A. L., Apr 4 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2219254120.Research output: Contribution to journal › Article › peer-review
Open Access -
Alzheimer's disease and related dementias is a risk factor for lower utilization of breast cancer screening and unstaged cancer diagnosis: Observational study from SEER-Medicare 2004–2016 data
Weng, X., Shen, C., Vasekar, M., Boltz, M., Joshi, M., Van Scoy, L. J. & Wang, L., Apr 2023, In: Journal of Geriatric Oncology. 14, 3, 101407.Research output: Contribution to journal › Article › peer-review
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Collaborative Research: Multimodal Mapping of Gene Isoforms by Electromicrofluidic Manipulation
7/1/23 → 6/30/26
Project: Research project
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Diversity Supplement: Manipulation of Host Tissue to Induce a Hierarchical Microvasculature
National Heart, Lung, and Blood Institute
5/1/23 → 4/30/24
Project: Research project
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CAREER: Smart and scalable approaches for developing multimodal optical and acoustic imaging technologies
3/1/23 → 2/29/28
Project: Research project
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Early clinial trials for Angelica herbal supplements for prostate cancer interception
Lu, J. J. & Joshi, M.
9/1/22 → 8/31/24
Project: Research project
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Dual-Modality Ultrasound and Photoacoustic Molecular Imaging Strategies for Aggressive Prostate Cancer Detection
9/1/22 → …
Project: Research project
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Notch Pathway Activation Promotes the Adaptation of Metastatic Lung Cancer Cells to the Brain Microenvironment
9/1/21 → …
Project: Research project
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Collaborative Research: An implantable intracranial ultrasound stimulation for treating neurodiseases
8/15/21 → 7/31/24
Project: Research project
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Collaborative Research: Infection mechanisms of bacteriophages targeting motile bacteria
6/1/21 → 5/31/24
Project: Research project
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Delineating novel mechanism of immune evasion in melanoma brain metastases
1/1/21 → …
Project: Research project
Activities
- 3 Oral presentation
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Motivations and Potential for a 3D Image Informatics for Histopathology (Panel Discussion)
Keith Cheng (Speaker)
Nov 4 2017Activity: Talk types › Oral presentation
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From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics
Keith Cheng (Speaker), Y Ding (Speaker), SR Katz (Speaker), AY Lin (Speaker), D van Rossum (Speaker) & D Vanselow (Speaker)
Sep 27 2017Activity: Talk types › Oral presentation
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Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish
Keith Cheng (Speaker), Y Ding (Speaker), AY Lin (Speaker), M Yakovlev (Speaker), D Vanselow (Speaker), X Xin (Speaker), S Katz (Speaker), D Vanselow (Speaker) & PJ La Riviere (Speaker)
Jul 5 2017Activity: Talk types › Oral presentation
Prizes
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American Orthopaedic Association C. Howard Hatcher Pathology Fellowship Award
Fox, Edward (Recipient), 2001
Prize
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Bausch & Lomb Science Award for Outstanding Achievement in Chemistry
Fox, Edward (Recipient), 1987
Prize
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Best Doctors in America
Fox, Edward (Recipient), Clebak, Karl (Recipient), Juliano, Paul (Recipient) & McGinn, Johnathan (Recipient), 2016
Prize
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Dean's Award for Excellence in Teaching
McAlevy, Mary (Recipient), Bonavia, Anthony (Recipient), Malhotra, Anita (Recipient), Weller, Gregory E. (Recipient), Waning, David (Recipient), Lanza, Matthew (Recipient), Ken, Kimberly (Recipient), McCarver, Stewart (Recipient), Glasser, Joshua (Recipient), Schooler, Jordan (Recipient), Lewis, Sarah (Recipient), Onks, Cayce (Recipient), Rao, Ravishankar (Recipient), Nickolich, Sarah (Recipient), Helm, Leesha (Recipient), Critchfield, Laura (Recipient), Myers, Kimberly (Recipient), Green, Michael (Recipient), Songdej, Natthapol (Recipient), Narayana, Shyam (Recipient), Razjouyan, Hadie (Recipient), Duca, Nicholas (Recipient), Casas, Rachel (Recipient), Cooper, Jennifer (Recipient), Wright, Rollin (Recipient), Karasinski, Amanda (Recipient), Probolus, James Andrew "Andy" (Recipient), Madara, John (Recipient), Guck, Daniel (Recipient), Ingram, David (Recipient), De Obaldia, Anna (Recipient), Hussein, Rezhan (Recipient), McGillen, Brian (Recipient), Chapman, Tyler (Recipient), Munyon, Ryan (Recipient), Kinard, Shane R. (Recipient), Banks, Sharon (Recipient), Genao, Inginia (Recipient), McShane, Michael (Recipient), Allie, S. Rameeza (Recipient), Silberman, Yuval (Recipient), Evey, Loren (Recipient), McLaughlin, Patricia (Recipient), Grogan, James (Recipient), Nguyen, Joseph (Recipient), Donato, Heather (Recipient), Fox, Edward (Recipient), Gniady, John (Recipient), Oladipo, Olajumoke (Recipient), Abendroth, Catherine (Recipient), Keefer, Laura (Recipient), Massare, Brittany (Recipient), Undar, Akif (Recipient), Mondal, Pritish (Recipient), Mainali, Gayatra (Recipient), Jhaveri, Pooja (Recipient), Freiberg, Andrew (Recipient), Levenson, Robert (Recipient), Mailman, Richard (Recipient), Boodoo, Ramnarine (Recipient), Francis, Andrew (Recipient), Hameed, Usman (Recipient), Yadav, Sanjay (Recipient), Calo, William (Recipient), Pinto, Casey (Recipient), Cooper, Amanda (Recipient), Kulaylat, Audrey (Recipient), Scow, Jeffrey (Recipient), Roberts, John (Recipient), Winder, Joshua (Recipient), Aminsharifi, Alireza (Recipient), Adams, Nancy (Recipient) & van Riggelen, Jan (Recipient), 2023
Prize
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Dean’s Award for Excellence in Teaching
Hollins, L. Claire (Recipient), Nisnevitch-Savarese, Zoulfira (Recipient), Read, Selina (Recipient), Rossi, John (Recipient), Royo, Marc (Recipient), Sarraf, Elie (Recipient), Shah, Bunty (Recipient), Moldovan, George-Lucian (Recipient), van Riggelen, Jan (Recipient), Shantz, Lisa (Recipient), Yengo, Christopher (Recipient), Booth, Jennifer (Recipient), Bates, Erica (Recipient), Schuster, Angel (Recipient), Clebak, Karl (Recipient), Daniels, Eldra W. (Recipient), Hays, Amy (Recipient), Hemerly, Nathan (Recipient), Thompson, Andrew (Recipient), George, Daniel (Recipient), Evey, Loren (Recipient), McLaughlin, Patricia (Recipient), Acharya, Jayant (Recipient), De Jesus, Sol (Recipient), O'Leary, Amber (Recipient), Wright, Tonya (Recipient), Cantore, William (Recipient), Pantanelli, Seth (Recipient), Millard, Roberta (Recipient), Updegrove, Gary F. (Recipient), Choi, Karen (Recipient), Darowish, Charles (Recipient), Dooley, Amy (Recipient), Hackman, Nicole (Recipient), Krawiec, Conrad (Recipient), Oji-Mmuo, Christiana (Recipient), Ryan, Sheryl (Recipient), Shedlock, Aaron (Recipient), Tunks, Robert (Recipient), Critchfield, Laura (Recipient), Bellon, Alfredo (Recipient), Dougherty, Kathleen (Recipient), Lagman, Jasmin (Recipient), Mahgoub, Yassir (Recipient), Dreibelbis, Tomi (Recipient), Richie, John (Recipient), Wang, Li (Recipient), Methratta, Sosamma (Recipient), Chauvin, Nancy (Recipient), Deutsch, Michael (Recipient), Kulaylat, Afif (Recipient), Paulishak, Melody (Recipient), Staszak, Ryan (Recipient) & MacDonald, Susan (Recipient), 2022
Prize
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Excellence in Career Mentoring Award
Waxmonsky, James (Recipient), Connor, James (Recipient), Pantanelli, Seth (Recipient) & Shen, Chan (Recipient), 2022
Prize
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