Organization profile
Organization profile
The Experimental Therapeutics research program at Penn State Cancer Institute discovers and characterizes novel agents and pathways; translates these discoveries through innovative, preclinical proof-of-principle studies; and provides more effective cancer therapies to patients.
Program members also collaborate with colleagues in biomedical engineering at Penn State University Park, as well as with Cancer Control research program members, regarding the role of exercise in treatment outcomes for cancer patients. Additional collaborations involve work with the Mechanisms of Carcinogenesis research program on the identification of genomic markers in metastatic melanoma as potential markers of response.
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Collaborations and top research areas from the last five years
Profiles
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Reka Z. Albert, PhD
- Physics - Distinguished Professor
- Huck Institutes of the Life Sciences
- Penn State Cancer Institute
- Cancer Institute, Experimental Therapeutics
Person: Academic
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Marco Archetti
- Biology - Associate Professor
- Huck Institutes of the Life Sciences
- Penn State Cancer Institute
- Cancer Institute, Experimental Therapeutics
Person: Academic
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Dawit Aregawi, MD
- Department of Neurosurgery - Assistant Professor
- Penn State Cancer Institute
- Penn State Neuroscience Institute
- Cancer Institute, Experimental Therapeutics
Person: Academic
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Anilchandra Attaluri
- School of Science, Engineering & Technology (Harrisburg) - Associate Professor Of Mechanical Engineering
- Penn State Cancer Institute
- Cancer Institute, Experimental Therapeutics
Person: Academic
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James Broach, PhD
- Department of Molecular and Precision Medicine - Distinguished Professor
- Department of Otolaryngology - Head and Neck Surgery - Professor
- Institute for Personalized Medicine - Director
- Penn State Cancer Institute
- Cancer Institute, Experimental Therapeutics
Person: Academic
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Keith Cheng, MD, PhD
- Department of Pathology and Laboratory Medicine - Distinguished Professor
- Division of Experimental Pathology
- Department of Molecular and Precision Medicine - Distinguished Professor
- Penn State Cancer Institute
- Huck Institutes of the Life Sciences
- Institute for Computational and Data Sciences (ICDS)
- Cancer Institute, Experimental Therapeutics
Person: Academic
Research output
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1234: A MEDICAL PASSPORT FOR SAFER JOURNEYS: MINIMIZING ERRORS FOR CHILDREN WITH MEDICAL COMPLEXITY
Finney, M., Kerris, E., Thomas, N., Halstead, E. S., DeMartini, T. & Dooley, A., Mar 2026, In: Critical care medicine. 54, 3SResearch output: Contribution to journal › Article › peer-review
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1387: SELECTIVE REVERSAL OF IL-1-MEDIATED CYTOKINE STORM USING ANAKINRA FOR SEPSIS-INDUCED MODS
Blade, R., Hahn, T., McKeone, D., Ericson, J., DeMartini, T. & Halstead, E. S., Mar 2026, In: Critical care medicine. 54, 3SResearch output: Contribution to journal › Article › peer-review
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1720: INFLAMMATORY ENDOTYPES OF SEPSIS: PRECLINICAL MODELS AND CLINICAL INVESTIGATION
Halstead, E. S., Umstead, T., Riccio-Baum, C., McKeone, D., Spear, D., Rameeza Allie, S. & Chroneos, Z., Mar 2026, In: Critical care medicine. 54, 3SResearch output: Contribution to journal › Article › peer-review
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3D-Printed Gastrointestinal Stents: In Vivo Evaluation in a Swine Small Bowel Perforation Model
Capron, G., Fathi, P., Jensen, T. W., Milner, D. J., van der Vlies, A. J., Moody, R. L., Bangert, E. A., Rowitz, B., Pan, D. & Wheeler, M. B., Mar 20 2026, In: Advanced Healthcare Materials. 15, 11, e05169.Research output: Contribution to journal › Article › peer-review
Open Access -
Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia
Ung, J., Tan, S. F., Shaw, J. J. P., Taori, M., Deddens, T. M., Venancio, G., Montgomery, M. M., Hagen, J. T., Aruleba, R. T., Golla, U. R., Sharma, A., Paudel, B. B., Lee, I., Ramamoorthy, B., Janes, K. A., Garrett-Bakelman, F., Cabot, M. C., Fisher-Wellman, K. H., Fox, T. E. & Claxton, D. F. & 3 others, , May 2026, In: Blood Neoplasia. 3, 2, 100196.Research output: Contribution to journal › Article › peer-review
Open Access -
A clade-specific, amplification-free molecular lateral flow platform for on-site detection of Mpox
Natarajan, S., Dighe, K., Skrodzki, D., Ponnusamy, N. & Pan, D., Mar 17 2026, In: Chemical Communications. 62, 21, p. 5895-5899 5 p.Research output: Contribution to journal › Article › peer-review
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A Compact Microwave Heating Platform Complemented by Nonlinear Model-Based Closed-Loop Temperature Control
Pawar, S., Ghimirey, B., Attaluri, A. C. & Tofighi, M. R., Mar 1 2026, In: IEEE Journal of Microwaves. 6, 2, p. 540-549 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 1: intraoperative recommendations for mapping, monitoring, and decision making
Gerritsen, J. K. W., Karschnia, P., Bello, L., Hervey-Jumper, S., Young, J. S., Seidel, K., Satoer, D. D., Schnell, O., Parsons, M., Nahed, B. V., Menna, G., Teske, N., Ashkan, K., Barberis, M., Bettegowda, C., Boele, F., Byrne, R. W., Cahill, D. P., Delev, D. & De Witte, E. & 45 others, , Jan 2026, In: The Lancet Oncology. 27, 1, p. e11-e23Research output: Contribution to journal › Review article › peer-review
1 Link opens in a new tab Scopus citations -
A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 2: perioperative recommendations for neurological, language, functional, and quality-of-life assessment
Gerritsen, J. K. W., Karschnia, P., Bello, L., Hervey-Jumper, S., Young, J. S., Seidel, K., Satoer, D. D., Schnell, O., Parsons, M., Nahed, B. V., Menna, G., Teske, N., Ashkan, K., Barberis, M., Bettegowda, C., Boele, F., Byrne, R. W., Cahill, D. P., Delev, D. & De Witte, E. & 45 others, , Jan 2026, In: The Lancet Oncology. 27, 1, p. e24-e32Research output: Contribution to journal › Review article › peer-review
1 Link opens in a new tab Scopus citations -
ACR Appropriateness Criteria® Chronic Foot Pain: Update 2025
Expert Panel on Musculoskeletal Imaging:, Apr 2026, In: Journal of the American College of Radiology. 23, 4, p. 681-699 19 p.Research output: Contribution to journal › Article › peer-review
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Ceramide-Directed Therapeutics for Treatment of AML
Loughran, T. T. P. (PI), Chalfant, C. C. E. (CoPI), Claxton, D. (CoPI), Zhu, H. H. (CoPI), Fisher-wellman, K. K. H. (CoPI), Janes, K. A. (CoPI) & Fox, T. E. (CoPI)
9/1/25 → 8/31/26
Project: Research project
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Pennsylvania Colorectal Cancer Alliance to Reduce Mortality and Enhance Screening (PA-CARES)
Randal, F. (PI), Kim, K. (CoI), Hohl, R. (CoI), Ruffin, M. (CoI), Calo, W. (CoI), Maranki, J. (CoI), Felix, T. (CoI), Leibovitz, D. (CoI) & Lozano, P. (CoI)
Centers for Disease Control and Prevention
8/30/25 → 8/29/30
Project: Research project
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Targeting extracellular vesicles in neuroblastoma
Spiegelman, V. (PI) & Wang, H.-G. (CoPI)
8/11/25 → 7/31/26
Project: Research project
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3D structural and mechanistic underpinnings of the eu/heterochromatin dichotomy
Grigoryev, S. (PI) & Mts286@psuedu, M. T. S. (CoPI)
8/1/25 → 7/31/28
Project: Research project
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Preclinical Evaluation of a Peptide-amphiphile Derived Toroidal Oxygen Carrier
Pan, D. (PI), Doctor, A. (CoPI), Aluru, N. R. (CoPI) & Buehler, P. (CoPI)
National Heart, Lung, and Blood Institute
2/1/25 → 11/30/26
Project: Research project
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A portable photoacoustic imager for diagnosing vascular diseases
Kothapalli, S.-R. (PI)
National Institute of Biomedical Imaging and Bioengineering
9/1/24 → 8/31/26
Project: Research project
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3D Printing of Air: An Intangible Ink for Fabrication of Vascularized Tissues
Ozbolat, I. T. (PI) & Ravnic, D. (CoPI)
National Institute of Biomedical Imaging and Bioengineering
7/9/24 → 4/30/27
Project: Research project
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Non-covalent functionalization of collagen for growth factor delivery using bispecific aptamers
Wang, Y. (PI)
National Institute of Biomedical Imaging and Bioengineering
5/15/24 → 2/28/27
Project: Research project
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Targeting ß-TrCP regulators to improve CRC response to chemotherapy
Spiegelman, V. (PI) & Fuchs, S. S. Y. (CoPI)
3/5/24 → 2/28/27
Project: Research project
Activities
- 3 Oral presentation
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Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish
Cheng, K. (Speaker), Ding, Y. (Speaker), Lin, A. (Speaker), Yakovlev, M. (Speaker), Vanselow, D. (Speaker), Xin, X. (Speaker), Katz, S. (Speaker), Vanselow, D. (Speaker) & La Riviere, P. (Speaker)
Jul 5 2017Activity: Talk types › Oral presentation
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Motivations and Potential for a 3D Image Informatics for Histopathology (Panel Discussion)
Cheng, K. (Speaker)
Nov 4 2017Activity: Talk types › Oral presentation
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From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics
Cheng, K. (Speaker), Ding, Y. (Speaker), Katz, S. (Speaker), Lin, A. (Speaker), van Rossum, D. (Speaker) & Vanselow, D. (Speaker)
Sep 27 2017Activity: Talk types › Oral presentation
Prizes
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American Orthopaedic Association C. Howard Hatcher Pathology Fellowship Award
Fox, E. (Recipient), 2001
Prize
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Best Doctors in America
Fox, E. (Recipient), Clebak, K. (Recipient), Juliano, P. (Recipient) & McGinn, J. (Recipient), 2016
Prize
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Dean's Award for Excellence in Teaching
McAlevy, M. (Recipient), Bonavia, A. (Recipient), Malhotra, A. (Recipient), Weller, G. E. (Recipient), Waning, D. (Recipient), Lanza, M. (Recipient), Ken, K. (Recipient), McCarver, S. (Recipient), Glasser, J. (Recipient), Schooler, J. (Recipient), Lewis, S. (Recipient), Onks, C. (Recipient), Rao, R. (Recipient), Nickolich, S. (Recipient), Helm, L. (Recipient), Critchfield, L. (Recipient), Myers, K. (Recipient), Green, M. (Recipient), Songdej, N. (Recipient), Narayana, S. (Recipient), Razjouyan, H. (Recipient), Duca, N. (Recipient), Casas, R. (Recipient), Cooper, J. (Recipient), Wright, R. (Recipient), Karasinski, A. (Recipient), Probolus, J. A. (Recipient), Madara, J. (Recipient), Guck, D. (Recipient), Ingram, D. (Recipient), De Obaldia, A. (Recipient), Hussein, R. (Recipient), McGillen, B. (Recipient), Chapman, T. (Recipient), Munyon, R. (Recipient), Kinard, S. R. (Recipient), Banks, S. (Recipient), Genao, I. (Recipient), McShane, M. (Recipient), Allie, S. R. (Recipient), Silberman, Y. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Grogan, J. (Recipient), Nguyen, J. (Recipient), Donato, H. (Recipient), Fox, E. (Recipient), Gniady, J. (Recipient), Oladipo, O. (Recipient), Abendroth, C. (Recipient), Keefer, L. (Recipient), Massare, B. (Recipient), Undar, A. (Recipient), Mondal, P. (Recipient), Mainali, G. (Recipient), Jhaveri, P. (Recipient), Freiberg, A. (Recipient), Levenson, R. (Recipient), Mailman, R. (Recipient), Boodoo, R. (Recipient), Francis, A. (Recipient), Hameed, U. (Recipient), Yadav, S. (Recipient), Calo, W. (Recipient), Pinto, C. (Recipient), Cooper, A. (Recipient), Kulaylat, A. (Recipient), Scow, J. (Recipient), Roberts, J. (Recipient), Winder, J. (Recipient), Aminsharifi, A. (Recipient), Adams, N. (Recipient) & van Riggelen, J. (Recipient), 2023
Prize
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Dean's Award for Excellence in Teaching
Hussein, R. (Recipient), Stredny, E. (Recipient), Whitley, M. (Recipient), Mnatsakanyan, N. (Recipient), Raimundo, N. (Recipient), Zarnescu, D. (Recipient), Adams, N. (Recipient), Lanza, M. (Recipient), Kowalczyk, A. (Recipient), Travelute, C. (Recipient), Marco, C. (Recipient), Tondt, J. (Recipient), Anderson, A. (Recipient), Heron, C. (Recipient), Newman, R. (Recipient), Richard, D. (Recipient), Scartozzi, C. (Recipient), Dellasega, C. (Recipient), Akhtar, N. (Recipient), Albano-Aluquin, S. (Recipient), Chisty, A. (Recipient), Crook, T. (Recipient), Federici, E. H. (Recipient), Ingram, D. (Recipient), Lakshmanan, P. (Recipient), Mathew, A. (Recipient), Narayana, S. (Recipient), Prokop, A. (Recipient), Razjouyan, H. (Recipient), Tariq, A. (Recipient), Thompson, B. (Recipient), Thompson, E. (Recipient), Trivedi, N. (Recipient), Van Scoy, L. (Recipient), Wong, J. (Recipient), Allie, S. R. (Recipient), Browning, K. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Mamarabadi, M. (Recipient), Shankar, L. (Recipient), Bowie, E. (Recipient), Petfield, J. (Recipient), Whitaker, M. (Recipient), Aynardi, J. (Recipient), Allen, N. (Recipient), Cunningham, B. (Recipient), Gandhi, C. (Recipient), Jairath, B. (Recipient), Lutzkanin, K. M. (Recipient), Kerris, E. (Recipient), Nelson, A. (Recipient), Shook, J. (Recipient), Proctor, E. A. (Recipient), Raup-Konsavage, W. (Recipient), Romanoski, N. (Recipient), Graziane, J. (Recipient), Llorente, A. (Recipient), Nutting, S. (Recipient), Pinto, C. (Recipient), Yingst, J. (Recipient), Zhou, S. (Recipient), Mahase, S. (Recipient), Brian, P. (Recipient), Goldman, E. (Recipient), Maffie, J. (Recipient), Brahmbhatt, R. (Recipient), Fahy, A. (Recipient), Gish, J. (Recipient), Reed, M. F. (Recipient) & Tomasko, J. (Recipient), 2024
Prize
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Dean’s Award for Excellence in Teaching
Hollins, L. C. (Recipient), Nisnevitch-Savarese, Z. (Recipient), Read, S. (Recipient), Rossi, J. (Recipient), Royo, M. (Recipient), Sarraf, E. (Recipient), Shah, B. (Recipient), Moldovan, G.-L. (Recipient), van Riggelen, J. (Recipient), Shantz, L. (Recipient), Yengo, C. (Recipient), Booth, J. (Recipient), Bates, E. (Recipient), Schuster, A. (Recipient), Clebak, K. (Recipient), Daniels, E. W. (Recipient), Hays, A. (Recipient), Hemerly, N. (Recipient), Thompson, A. (Recipient), George, D. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Acharya, J. (Recipient), De Jesus, S. (Recipient), O'Leary, A. (Recipient), Wright, T. (Recipient), Cantore, W. (Recipient), Pantanelli, S. (Recipient), Millard, R. (Recipient), Updegrove, G. F. (Recipient), Choi, K. (Recipient), Darowish, C. (Recipient), Dooley, A. (Recipient), Hackman, N. (Recipient), Krawiec, C. (Recipient), Oji-Mmuo, C. (Recipient), Ryan, S. (Recipient), Shedlock, A. (Recipient), Tunks, R. (Recipient), Critchfield, L. (Recipient), Bellon, A. (Recipient), Dougherty, K. (Recipient), Lagman, J. (Recipient), Mahgoub, Y. (Recipient), Dreibelbis, T. (Recipient), Richie, J. (Recipient), Wang, L. (Recipient), Methratta, S. (Recipient), Chauvin, N. (Recipient), Deutsch, M. (Recipient), Kulaylat, A. (Recipient), Paulishak, M. (Recipient), Staszak, R. (Recipient) & MacDonald, S. (Recipient), 2022
Prize
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Distinguished Educator Award
Behura, C. (Recipient), DeWaters, A. (Recipient), George, M. (Recipient) & Williams, E. (Recipient), 2024
Prize
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Excellence in Career Mentoring Award
Waxmonsky, J. (Recipient), Connor, J. (Recipient), Pantanelli, S. (Recipient) & Shen, C. (Recipient), 2022
Prize