Chemistry

Postal address
United States

GaneshSrinivasan Anand
- Chemistry - Associate Professor
- Huck Institutes of the Life Sciences
Person: Academic
19972025
John B. Asbury
- Chemistry - Professor
Person: Academic
19982025
Stephen Benkovic
- Chemistry - Atherton Professor, Evan Pugh University Professor and Eberly Chair
Person: Academic
1963 …2025
Philip C. Bevilacqua
- Biochemistry & Molecular Biology
- Chemistry - Professor
- Plant Institute
Person: Academic
19892025
Amie Kathleen Boal
- Biochemistry & Molecular Biology
- Chemistry - Professor
Person: Academic
20052025
David D. Boehr, PhD
- Chemistry - Professor of Chemistry
- Penn State Cancer Institute
- Cancer Institute, Mechanisms of Carcinogenesis
Person: Academic
20002025
Joseph M. Bollinger, Jr.
- Biochemistry & Molecular Biology
- Chemistry - Professor
Person: Academic
19892025
Chen Chen
- Chemistry - Associate Research Professor
Person: Academic
20082025
Joseph Alfred Cotruvo, Jr.
- Eberly College of Science - Professor
- Chemistry - Professor
Person: Academic
20082025
Paul S. Cremer
- Eberly College of Science - J. Lloyd Huck Chair in Natural Sciences
- Biochemistry & Molecular Biology
- Chemistry - Professor
Person: Academic
19952025

479745 Citations
282 h-index
5942 Article
295 Review article
174 Conference contribution
147 Comment/debate
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A [FeFe] Hydrogenase-Rubrerythrin Chimeric Enzyme Functions to Couple H₂ Oxidation to Reduction of H₂O₂ in the Foodborne Pathogen Clostridium perfringens
Taylor, J., Mulder, D. W., Corrigan, P. S., Ratzloff, M. W., Irizarry Gonzalez, N., Lubner, C. E., King, P. W. & Silakov, A., Mar 19 2025, In: Journal of the American Chemical Society. 147, 11, p. 9764-9773 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
A General Amino-(Hetero)arylation of Simple Olefins with (Hetero)aryl Sulfonamides Enabled by an N-Triazinyl Group
Barney, J. L., Wolfram, A. J., Litvak, R. & Nacsa, E. D., Feb 7 2025, In: ACS Catalysis. 15, 3, p. 2139-2149 11 p.
Research output: Contribution to journal › Article › peer-review
5 Scopus citations
A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities
Dannenberg, R. L., Cardina, J. A., Washington, H., Gao, S., Greenberg, M. M. & Hedglin, M., Jul 22 2025, In: Nucleic acids research. 53, 13, gkaf646.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
An Electrochemical Design for a General Catalytic Carboxylic Acid Substitution Platform via Anhydrides at Room Temperature: Amidation, Esterification, and Thioesterification
Han, J., Piane, J. J., Gizenski, H., Elacqua, E. & Nacsa, E. D., Feb 28 2025, In: Organic Letters. 27, 8, p. 1923-1928 6 p.
Research output: Contribution to journal › Article › peer-review
4 Scopus citations
A New Landmark for Reticular Chemistry: Celebrating the Nobel Prize for Metal–Organic Frameworks
Millstone, J. E., Buriak, J. M., Chen, X., Liz-Marzán, L. M. & Schaak, R. E., Nov 11 2025, In: ACS nano. 19, 44, p. 38187-38188 2 p.
Research output: Contribution to journal › Editorial › peer-review
A roadmap for next-generation nanomotors
Chen, S., Fan, D. E., Fischer, P., Ghosh, A., Göpfrich, K., Golestanian, R., Hess, H., Ma, X., Nelson, B. J., Patiño Padial, T., Tang, J., Villa, K., Wang, W., Zhang, L., Sen, A. & Sánchez, S., Aug 2025, In: Nature nanotechnology. 20, 8, p. 990-1000 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen
Peduzzi, O. M., Palowitch, G. M., Gajewski, J. P., Hu, K., Wheeler, A., Laremore, T. N., Silletti, S., Komives, E. A., Allen, B. D., Silakov, A., Krebs, C., Bollinger, Jr., J. M., Lin, C. Y. & Boal, A. K., Sep 16 2025, In: Biochemistry. 64, 18, p. 3935-3955 21 p.
Research output: Contribution to journal › Article › peer-review
A tale of two dimers: lanthanide recognition at biomolecular interfaces
Larrinaga, W. B. & Cotruvo, J. A., 2025, (Accepted/In press) In: Trends in Biochemical Sciences.
Research output: Contribution to journal › Review article › peer-review
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection
Derman, I. D., Alioglu, M. A., Moses, J. C., Chroneos, Z. C., Yilmaz, Y. O., Banerjee, D., Koff, J., Rizvi, S. H. A., Klunk, D. N., Celik, N., Pochareddy, S., Umstead, T. M., Namli, I., Holton, S. E., Mikacenic, C., Thompson, J. L., Castaneda, D. C., Hickey, D. R., Nagamine, M. & Warang, P. & 5 others, Schotsaert, M., Chen, P., Peeples, M. E., Palucka, K. & Ozbolat, I. T., Jul 2025, In: Trends in Biotechnology. 43, 7, p. 1714-1742 29 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Azetidine amino acid biosynthesis by non-haem iron-dependent enzymes
Du, Y., Thanapipatsiri, A., Blancas Cortez, J. J., Salas-Solá, X. E., Lin, C. Y., Boal, A. K., Krebs, C., Bollinger, Jr., J. M. & Yokoyama, K., 2025, (Accepted/In press) In: Nature Chemistry.
Research output: Contribution to journal › Article › peer-review

Open Access

56 Active
357 Finished

Collaborative Research: Predictive Framework for Harnessing Order-Disorder Phenomena in Mixed-Chalcogen Solids
Hodges, J. (PI)
National Science Foundation
10/1/25 → 9/30/28
Project: Research project
Chemical Control over the Formation and Reactivity of High Entropy Nanoparticles
Schaak, R. E. (PI)
National Science Foundation
9/1/25 → 8/31/28
Project: Research project
Collaborative Research: Using Nonlinear Light Scattering to Unravel the Chemical Effects in Surface Enhanced Spectroscopy
Jensen, L. (PI)
National Science Foundation
9/1/25 → 8/31/28
Project: Research project
Surface Access Gating by Excited States (SAGE) for Quantum Dot Photocatalysis
Asbury, J. B. (PI)
Basic Energy Sciences
9/1/25 → 6/30/28
Project: Research project
Teaching the Design of Data Visualization using Artificial Intelligence
Lear, B. J. (PI) & Grove, N. (CoPI)
National Science Foundation
9/1/25 → 8/31/28
Project: Research project
Production of Ethylene and 3-Hydroxypropionate from the Common Metabolite, 2-Oxoglutarate, by the Ethylene-Forming Enzyme (EFE)
Krebs, C. C. (PI), Bollinger, Jr., J. M. (CoPI), Boal, A. K. (CoPI) & Sayfutyarova, E. (CoPI)
Basic Energy Sciences
9/1/25 → 2/28/27
Project: Research project
Acetyllysine Structure-Function Analysis by 13C Direct-Detect NMR Spectroscopy
Showalter, S. A. (PI)
National Institute of General Medical Sciences
7/1/25 → 3/31/26
Project: Research project
Virus breathing and assembly-disassembly transitions in host-entry
Anand, G. (PI)
National Institute of General Medical Sciences
6/1/25 → 5/31/26
Project: Research project
Carbon-Detected NMR Studies of Intrinsically Disordered Proteins in Promoter Proximal Pausing
Showalter, S. A. (PI)
National Science Foundation
2/15/25 → 1/31/28
Project: Research project
Liquid-Liquid Phase Separation in Submicron Aerosol Particles
Freedman, M. A. (PI)
Basic Energy Sciences
9/1/24 → 6/30/27
Project: Research project

Chemistry

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Collaborations and top research areas from the last five years

Dive into details

GaneshSrinivasan Anand

John B. Asbury

Stephen Benkovic

Philip C. Bevilacqua

Amie Kathleen Boal

David D. Boehr, PhD

Joseph M. Bollinger, Jr.

Chen Chen

Joseph Alfred Cotruvo, Jr.

Paul S. Cremer

A [FeFe] Hydrogenase-Rubrerythrin Chimeric Enzyme Functions to Couple H₂ Oxidation to Reduction of H₂O₂ in the Foodborne Pathogen Clostridium perfringens

A General Amino-(Hetero)arylation of Simple Olefins with (Hetero)aryl Sulfonamides Enabled by an N-Triazinyl Group

A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities

An Electrochemical Design for a General Catalytic Carboxylic Acid Substitution Platform via Anhydrides at Room Temperature: Amidation, Esterification, and Thioesterification

A New Landmark for Reticular Chemistry: Celebrating the Nobel Prize for Metal–Organic Frameworks

A roadmap for next-generation nanomotors

A Structurally Divergent Class Ia Ribonucleotide Reductase from a Tick-Borne Pathogen

A tale of two dimers: lanthanide recognition at biomolecular interfaces

A ventilated perfused lung model platform to dissect the response of the lungs to viral infection

Azetidine amino acid biosynthesis by non-haem iron-dependent enzymes

Collaborative Research: Predictive Framework for Harnessing Order-Disorder Phenomena in Mixed-Chalcogen Solids

Chemical Control over the Formation and Reactivity of High Entropy Nanoparticles

Collaborative Research: Using Nonlinear Light Scattering to Unravel the Chemical Effects in Surface Enhanced Spectroscopy

Surface Access Gating by Excited States (SAGE) for Quantum Dot Photocatalysis

Teaching the Design of Data Visualization using Artificial Intelligence

Production of Ethylene and 3-Hydroxypropionate from the Common Metabolite, 2-Oxoglutarate, by the Ethylene-Forming Enzyme (EFE)

Acetyllysine Structure-Function Analysis by 13C Direct-Detect NMR Spectroscopy

Virus breathing and assembly-disassembly transitions in host-entry

Carbon-Detected NMR Studies of Intrinsically Disordered Proteins in Promoter Proximal Pausing

Liquid-Liquid Phase Separation in Submicron Aerosol Particles

Chemistry

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Projects