Department of Cell and Biological Systems

Websitehttps://med.psu.edu/departments-faculty/cell-and-biological-systems

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United States

Samina Alam, MS, PhD
- Department of Cell and Biological Systems - Research Associate
Person: Academic
19962025
S. Rameeza Allie, PhD, MS
- Department of Cell and Biological Systems - Assistant Professor
Person: Academic
20022025
Shyam Bansal, MS, PhD, MS
- Department of Medicine - Associate Professor
- Department of Cell and Biological Systems - Associate Professor
Person: Academic
20072026
Alistair Barber, PhD
- Department of Ophthalmology - Professor
- Department of Cell and Biological Systems - Professor
- Penn State Neuroscience Institute
Person: Academic
19892025
Elisa Bradley, MD
- Department of Medicine - Associate Professor
- Division of Cardiology
- Department of Cell and Biological Systems - Associate Professor
- Penn State Heart and Vascular Institute
Person: Academic
20082026
Gerd Brunner, PhD, MSc
- Department of Medicine - Associate Professor
- Division of Cardiology
- Department of Cell and Biological Systems - Associate Professor
Person: Academic
20052025
Neil Christensen, MSc, PhD
Person: Academic
19832026
Zissis Chroneos, PhD
- Department of Pediatrics - Professor
- Division of Hematology and Oncology
- Department of Cell and Biological Systems - Professor
Person: Academic
19872026
Marina Chulkina, PhD
- Department of Medicine - Assistant Professor
- Department of Cell and Biological Systems - Assistant Professor
Person: Academic
20062026
Michael Dennis, PhD
- Department of Cell and Biological Systems - Professor
- Department of Ophthalmology - Professor
Person: Academic
20072025

2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
Gurvitz, M., Krieger, E. V., Fuller, S., Davis, L. L., Kittleson, M. M., Aboulhosn, J. A., Bradley, E. A., Buber, J., Daniels, C. J., Dimopoulos, K., Egbe, A., Geoffrion, T. R., John, A., Khairy, P., Kim, Y. Y., Kreutzer, J., Lewis, M. J., Menachem, J. N., Moore, J. P. & Osteen, K. A. & 6 others, Parikh, P. B., Saidi, A., Salciccioli, K. B., Schunder, R. L., Valente, A. M. & Wald, R. M., Feb 24 2026, In: Journal of the American College of Cardiology. 87, 7, p. 822-976 155 p.
Research output: Contribution to journal › Article › peer-review
12 Link opens in a new tab Scopus citations
A nuclear-targeted activity-based sensing probe for ratiometric imaging of formaldehyde reveals endogenous epigenetic contributors to the nuclear formaldehyde pool
Tenney, L., Wen, K. K., Han, S. S., Vyas, Y. M. & Chang, C. J., Feb 4 2026, In: Chemical Science. 17, 5, p. 2732-2740 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
CD28-deficient mice are vulnerable to mouse papillomavirus MmuPV1 infection of the skin and mucosae
Brendle, S., Li, J., Lu, S., Schell, T. D., Kozak, M., Walter, V., Shearer, D., Place, J., Balogh, K., Casanova, J. L., Christensen, N., Burgener, A. D., Murooka, T. T., Zhu, Y., Béziat, V. & Hu, J., Mar 2026, In: PLoS pathogens. 22, 3 March, e1013968.
Research output: Contribution to journal › Article › peer-review

Open Access
Coenzyme A mitigates cystine-deprivation-induced ferroptosis by suppressing the iron-starvation response
Tan, M., Li, Y., Sang, L., Wang, M., Li, Q., Li, Z., Sun, D., Wang, X. & Yang, S., 2026, (Accepted/In press) In: FEBS Journal.
Research output: Contribution to journal › Article › peer-review

Open Access
Correction: Three-dimensional Models of the Nasopharynx for the Study of Epstein-Barr Virus Infection (Bio-protocol (2022) 12:6 (e4365) DOI: 10.21769/BioProtoc.4365)
Ziegler, P., Reznik, A. S., Kitchloo, S. P., Wang, E., Lee, S. E., Green, A., Myerburg, M. M., Sample, C. E. & Shair, K. H. Y., Jan 20 2026, In: Bio-protocol. 16, 2, e5603.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
Cryo-EM structures of HBV capsids from human cells at near-atomic resolution
Bianchini, E. N., Pérez-Segura, C., Liu, H., Luckenbaugh, L., Flanagan, J., Cai, Y., Shanklin, J., Zlotnick, A., Hadden-Perilla, J. A., Hu, J. & C.-Y. Wang, J., Feb 5 2026, In: Structure. 34, 2, p. 240-253.e5
Research output: Contribution to journal › Article › peer-review

Open Access
2 Link opens in a new tab Scopus citations
Dynamins maintain nuclear envelope homeostasis and genome stability
Aveleira, C., Martial, T., Carrique, L., Gaspar, R., Caulino-Rocha, A., Myatt, I., Wendler, F., Lascaux, P., Le Claire, M., Bancroft, J., Smythe, C., Ramadan, K., Raimundo, N. & Milosevic, I., Dec 2026, In: Nature communications. 17, 1, 1380.
Research output: Contribution to journal › Article › peer-review

Open Access
Long-chain fatty acid utilization in Eisenmenger syndrome
Cavus, O., Oza, M. J., Angelotti, A., DeSalvo, J., Koo, I., Ruiz-Velasco, V. & Bradley, E. A., Jan 1 2026, In: Progress in Pediatric cardiology. 80, 101902.
Research output: Contribution to journal › Article › peer-review

Open Access
Machine learning integrated extracellular vesicle proteome analysis for early markers of bronchopulmonary dysplasia
Amatya, S., Rice, S., Stanley, A., Chen, H., Donnelly, A., Stephens, H., Siddaiah, R., Belani, C. & Chroneos, Z. C., Apr 1 2026, In: Function. 7, 2, p. e0902025
Research output: Contribution to journal › Article › peer-review

Open Access
Neuroprotection and antiaging effects of caloric restriction
Dias, R. A., Mendes, C., Raimundo, N. & Domingues, N., Jan 1 2026, Nutritional Neuroscience: From Bench to Bedside. Elsevier, p. 221-233 13 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter

Open Access

12 Active
18 Finished

Regulation of the cGAS-STING pathway by RNF11
Harhaj, E. (PI)
National Institute of Allergy and Infectious Diseases
7/7/25 → 6/30/27
Project: Research project
Cross validation of gene expression changes in C9orf72 FTD using Drosophila and human model systems
Zarnescu, D. (PI) & Sattler, R. R. (CoPI)
National Institute of Neurological Disorders and Stroke
6/1/25 → 5/31/27
Project: Research project
The BD FACSDiscover S8 Cell Sorter for Flow Cytometric Sorting
Schell, T. (PI)
NIH Office of the Director
5/15/25 → 5/14/26
Project: Research project
Mechanisms underlying TDP-43 dependent structural deficits in ALS muscles
Zarnescu, D. (PI) & Pasinelli, P. P. (CoPI)
National Institute on Aging
5/1/25 → 4/30/27
Project: Research project
ZFAND6 regulation of mitophagy and inflammation
Harhaj, E. (PI)
National Institute of Allergy and Infectious Diseases
2/1/25 → 1/31/27
Project: Research project
SHePREG: Study of Heart function in PRE-Eclampsia during and after PreGnancy
Bradley, E. (PI)
National Heart, Lung, and Blood Institute
1/14/25 → 12/31/26
Project: Research project
Impact of dilated cardiomyopathy mutations on cardiac myosin structure and function
Yengo, C. (PI), Warshaw, D. D. M. (CoPI) & Sivaramakrishnan, S. S. (CoPI)
National Heart, Lung, and Blood Institute
12/15/22 → 11/30/26
Project: Research project
Deciphering Early Stages of Polyomavirus CNS Pathogenesis and Immunity
Lukacher, A. (PI)
National Institute of Neurological Disorders and Stroke
5/1/22 → 4/30/26
Project: Research project
Negative regulation of innate immune signaling pathways by the selective autophagy receptor TAX1BP1
Harhaj, E. (PI)
National Institute of Allergy and Infectious Diseases
6/1/21 → 5/31/26
Project: Research project
Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach
Zarnescu, D. (PI)
Congressionally Directed Medical Research Programs
1/1/21 → …
Project: Research project

Department of Cell and Biological Systems

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Collaborations and top research areas from the last five years

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Samina Alam, MS, PhD

S. Rameeza Allie, PhD, MS

Shyam Bansal, MS, PhD, MS

Alistair Barber, PhD

Elisa Bradley, MD

Gerd Brunner, PhD, MSc

Neil Christensen, MSc, PhD

Zissis Chroneos, PhD

Marina Chulkina, PhD

Michael Dennis, PhD

2025 ACC/AHA/HRS/ISACHD/SCAI Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

A nuclear-targeted activity-based sensing probe for ratiometric imaging of formaldehyde reveals endogenous epigenetic contributors to the nuclear formaldehyde pool

CD28-deficient mice are vulnerable to mouse papillomavirus MmuPV1 infection of the skin and mucosae

Coenzyme A mitigates cystine-deprivation-induced ferroptosis by suppressing the iron-starvation response

Correction: Three-dimensional Models of the Nasopharynx for the Study of Epstein-Barr Virus Infection (Bio-protocol (2022) 12:6 (e4365) DOI: 10.21769/BioProtoc.4365)

Cryo-EM structures of HBV capsids from human cells at near-atomic resolution

Dynamins maintain nuclear envelope homeostasis and genome stability

Long-chain fatty acid utilization in Eisenmenger syndrome

Machine learning integrated extracellular vesicle proteome analysis for early markers of bronchopulmonary dysplasia

Neuroprotection and antiaging effects of caloric restriction

Regulation of the cGAS-STING pathway by RNF11

Cross validation of gene expression changes in C9orf72 FTD using Drosophila and human model systems

The BD FACSDiscover S8 Cell Sorter for Flow Cytometric Sorting

Mechanisms underlying TDP-43 dependent structural deficits in ALS muscles

ZFAND6 regulation of mitophagy and inflammation

SHePREG: Study of Heart function in PRE-Eclampsia during and after PreGnancy

Impact of dilated cardiomyopathy mutations on cardiac myosin structure and function

Deciphering Early Stages of Polyomavirus CNS Pathogenesis and Immunity

Negative regulation of innate immune signaling pathways by the selective autophagy receptor TAX1BP1

Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach

Department of Cell and Biological Systems

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Projects