Department of Molecular and Precision Medicine

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United States

Cesar Aliaga, MS
- Department of Molecular and Precision Medicine - Senior Research Associate
Person: Academic
19942026
Maria Bewley, PhD
- Penn State College of Medicine - Senior Scientific Director, Core Facilities
- Department of Molecular and Precision Medicine - Associate Professor
Person: Academic
19852024
Anthony Bonavia, MD
- Department of Anesthesiology and Perioperative Medicine - Professor
- Division of Critical Care Anesthesia
- Department of Molecular and Precision Medicine - Professor
Person: Academic
20062026
James Broach, PhD
- Department of Molecular and Precision Medicine - Distinguished Professor
- Department of Otolaryngology - Head and Neck Surgery - Professor
- Institute for Personalized Medicine - Director
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
19752025
Laura Carrel, MA, PhD
- Department of Molecular and Precision Medicine - Professor
- Huck Institutes of the Life Sciences
Person: Academic
19912025
Kun-Ming Chen, PhD, MS
- Department of Molecular and Precision Medicine - Associate Professor
- Penn State Cancer Institute
- Cancer Institute, Mechanisms of Carcinogenesis
Person: Academic
20042025
Keith Cheng, MD, PhD
- Department of Pathology and Laboratory Medicine - Distinguished Professor
- Division of Experimental Pathology
- Department of Molecular and Precision Medicine - Distinguished Professor
- Penn State Cancer Institute
- Huck Institutes of the Life Sciences
- Institute for Computational and Data Sciences (ICDS)
- Cancer Institute, Next-Generation Therapies
Person: Academic
19842025
Dhimant Desai, PhD
Person: Academic
19862025
Yali Ding, PhD
- Department of Pediatrics - Assistant Professor
- Department of Molecular and Precision Medicine - Assistant Professor
Person: Academic
20082025
Sinisa Dovat, PhD, MD
- Department of Pediatrics - Professor and Vice Chair for Basic Science Research
- Division of Hematology and Oncology
- Department of Molecular and Precision Medicine - Professor
- Penn State Cancer Institute
- Penn State Neuroscience Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
19912026

205262 Citations
192 h-index
3003 Article
319 Review article
75 Chapter
67 Comment/debate
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Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia
Ung, J., Tan, S. F., Shaw, J. J. P., Taori, M., Deddens, T. M., Venancio, G., Montgomery, M. M., Hagen, J. T., Aruleba, R. T., Golla, U. R., Sharma, A., Paudel, B. B., Lee, I., Ramamoorthy, B., Janes, K. A., Garrett-Bakelman, F., Cabot, M. C., Fisher-Wellman, K. H., Fox, T. E. & Claxton, D. F. & 3 others, Chalfant, C. E., Feith, D. J. & Loughran, T. P., May 2026, In: Blood Neoplasia. 3, 2, 100196.
Research output: Contribution to journal › Article › peer-review

Open Access
A Multilevel Analysis of Social Environmental Factors Related to Substance Use, Tobacco Use, and Binge Drinking Behaviors Among Older Adults
Zhang, X., Linn, B. K. & Moss, J. L., Jan 2026, In: American Journal of Preventive Medicine. 70, 1, 108115.
Research output: Contribution to journal › Article › peer-review

Open Access
An Epigenetic Basis for Sustained Inflammatory Epithelial Progenitor Cell States in Crohn’s Disease
Karakasheva, T. A., Martinez, C. M., Zhou, Y., Qui, J., Chen, X. E., Soto, G. E., Nettleford, S. K., Hix, O. T., Roach, D. M., Laguerta, A. M., Thadi, A., Edwards, R. M., Aleynick, D., Weinbrom, S., Borodyanskaya, E., Pickering, O. H., Fulton, M. K., Chen, C. H., Peterson, I. V. & Hagen, E. B. & 12 others, Yannuzzi, I. P., Haider, Z., Cramer, Z., Conrad, M. A., Li, N., Bewtra, M., Uzun, Y., Tan, K., Kelsen, J. R., Minn, A. J., Lengner, C. J. & Hamilton, K. E., 2026, In: CMGH. 20, 3, 101665.
Research output: Contribution to journal › Article › peer-review

Open Access
An Overview of the Mechanisms of HPV-Induced Cervical Cancer: The Role of Kinase Targets in Pathogenesis and Drug Resistance
Karnik, M., Tulimilli, S. R. V., Anantharaju, P. G., Bettadapura, A. D. S., Natraj, S. M., Mohideen, H. S., Dovat, S., Sharma, A. & Madhunapantula, S. R. V., Jan 2026, In: Cancers. 18, 2, 318.
Research output: Contribution to journal › Review article › peer-review

Open Access
1 Link opens in a new tab Scopus citations
CD28-deficient mice are vulnerable to mouse papillomavirus MmuPV1 infection of the skin and mucosae
Brendle, S., Li, J., Lu, S., Schell, T. D., Kozak, M., Walter, V., Shearer, D., Place, J., Balogh, K., Casanova, J. L., Christensen, N., Burgener, A. D., Murooka, T. T., Zhu, Y., Béziat, V. & Hu, J., Mar 2026, In: PLoS pathogens. 22, 3 March, e1013968.
Research output: Contribution to journal › Article › peer-review

Open Access
CHEK2 loss endows chemotherapy resistance to hematopoietic stem cells
Zhou, J., Hu, T., Li, D., Li, S., Li, M., Shi, X. & Nakada, D., Mar 2026, In: Leukemia. 40, 3, p. 511-521 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Chemotherapy-induced cognitive impairment (CICI): Cisplatin's effects on neurotransmitter regulation and oxidative stress in Drosophila melanogaster
Aziz, R. A., Venugopal, D. M., Kudva, A. K., Hanumanthappa, R., Mustak, M. S., Devaraju, K. S., Baliga, M. S. & Raghu, S. V., Jan 2026, In: NeuroToxicology. 112, 103365.
Research output: Contribution to journal › Article › peer-review
Cryo-EM structures of HBV capsids from human cells at near-atomic resolution
Bianchini, E. N., Pérez-Segura, C., Liu, H., Luckenbaugh, L., Flanagan, J., Cai, Y., Shanklin, J., Zlotnick, A., Hadden-Perilla, J. A., Hu, J. & C.-Y. Wang, J., Feb 5 2026, In: Structure. 34, 2, p. 240-253.e5
Research output: Contribution to journal › Article › peer-review

Open Access
2 Link opens in a new tab Scopus citations
Cutaneous clues to a fungal culprit: disseminated Blastomycosis presenting as inflammatory monoarthritis — a Case Report
Ssentongo, P., Akhtar, S., Perciuleac, Z., Kaye, C., Cherian, R. A., Garrett, E., Albano-Aluquin, S., Helm, T. N. & Parent, L. J., 2026, In: Frontiers in Medicine. 13, 1704751.
Research output: Contribution to journal › Article › peer-review

Open Access
Diversity-oriented rapid assembly of mercapto-1,2,4-triazoles and quinolines and exploring their cytotoxic activity for prostate and breast cancer cell lines
Panhotra, S., Raza, A., Singh, A., Sharma, A. K. & Gupta, P., Jan 5 2026, In: Journal of Molecular Structure. 1349, 143706.
Research output: Contribution to journal › Article › peer-review

18 Active
33 Finished

Post-transcriptional regulation of gene Expression during bone regeneration.
Elbarbary, R. (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/1/25 → 8/31/28
Project: Research project
Pennsylvania Colorectal Cancer Alliance to Reduce Mortality and Enhance Screening (PA-CARES)
Randal, F. (PI), Kim, K. (CoI), Hohl, R. (CoI), Ruffin, M. (CoI), Calo, W. (CoI), Maranki, J. (CoI), Felix, T. (CoI), Leibovitz, D. (CoI) & Lozano, P. (CoI)
Centers for Disease Control and Prevention
8/30/25 → 8/29/30
Project: Research project
3D structural and mechanistic underpinnings of the eu/heterochromatin dichotomy
Grigoryev, S. (PI) & Mts286@psuedu, M. T. S. (CoPI)
National Science Foundation
8/1/25 → 7/31/28
Project: Research project
Intestinal epithelial paracellular permeability and immune tolerance
Nighot, P. (PI)
National Institute of Allergy and Infectious Diseases
2/1/25 → 1/31/27
Project: Research project
Multi-omic Characterization of COPD in Females
Liu, D. (PI), Manichaikul, A. W. (CoPI) & Shim, Y. Y. M. (CoPI)
National Heart, Lung, and Blood Institute
8/1/24 → 7/31/26
Project: Research project
Methods and tools to integrate multi-omics datasets to understand preclinical autoimmune and immune-mediated diseases
Liu, D. (PI)
National Institute of Allergy and Infectious Diseases
7/5/24 → 5/31/26
Project: Research project
Autophagy and Hepatic Stellate cells activation
Nighot, P. (PI)
National Institute of Allergy and Infectious Diseases
6/1/24 → 4/30/26
Project: Research project
Targeting ß-TrCP regulators to improve CRC response to chemotherapy
Spiegelman, V. (PI) & Fuchs, S. S. Y. (CoPI)
National Cancer Institute
3/5/24 → 2/28/27
Project: Research project
Project 1: Translational Studies on Temperature and Solvent Effects on Electronic Cigarette-Derived Oxidants
Richie, J. (PI) & Spratt, T. (PI)
NATIONAL INSTITUTE ON DRUG ABUSE
9/30/23 → 8/31/26
Project: Research project
Penn State TCORS: Tobacco Product Composition Effects on Toxicity and Addiction
Muscat, J. (PI), Hobkirk, A. (CoPI), Sun, D. (CoPI), Richie, J. (CoPI), Foulds, J. (CoPI), Liao, J. J. (CoPI) & Spratt, T. (CoPI)
NATIONAL INSTITUTE ON DRUG ABUSE
9/30/23 → 8/31/26
Project: Research project

Department of Molecular and Precision Medicine

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Collaborations and top research areas from the last five years

Dive into details

Cesar Aliaga, MS

Maria Bewley, PhD

Anthony Bonavia, MD

James Broach, PhD

Laura Carrel, MA, PhD

Kun-Ming Chen, PhD, MS

Keith Cheng, MD, PhD

Dhimant Desai, PhD

Yali Ding, PhD

Sinisa Dovat, PhD, MD

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia

A Multilevel Analysis of Social Environmental Factors Related to Substance Use, Tobacco Use, and Binge Drinking Behaviors Among Older Adults

An Epigenetic Basis for Sustained Inflammatory Epithelial Progenitor Cell States in Crohn’s Disease

An Overview of the Mechanisms of HPV-Induced Cervical Cancer: The Role of Kinase Targets in Pathogenesis and Drug Resistance

CD28-deficient mice are vulnerable to mouse papillomavirus MmuPV1 infection of the skin and mucosae

CHEK2 loss endows chemotherapy resistance to hematopoietic stem cells

Chemotherapy-induced cognitive impairment (CICI): Cisplatin's effects on neurotransmitter regulation and oxidative stress in Drosophila melanogaster

Cryo-EM structures of HBV capsids from human cells at near-atomic resolution

Cutaneous clues to a fungal culprit: disseminated Blastomycosis presenting as inflammatory monoarthritis — a Case Report

Diversity-oriented rapid assembly of mercapto-1,2,4-triazoles and quinolines and exploring their cytotoxic activity for prostate and breast cancer cell lines

Post-transcriptional regulation of gene Expression during bone regeneration.

Pennsylvania Colorectal Cancer Alliance to Reduce Mortality and Enhance Screening (PA-CARES)

3D structural and mechanistic underpinnings of the eu/heterochromatin dichotomy

Intestinal epithelial paracellular permeability and immune tolerance

Multi-omic Characterization of COPD in Females

Methods and tools to integrate multi-omics datasets to understand preclinical autoimmune and immune-mediated diseases

Autophagy and Hepatic Stellate cells activation

Targeting ß-TrCP regulators to improve CRC response to chemotherapy

Project 1: Translational Studies on Temperature and Solvent Effects on Electronic Cigarette-Derived Oxidants

Penn State TCORS: Tobacco Product Composition Effects on Toxicity and Addiction

Department of Molecular and Precision Medicine

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Projects