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    500 University Dr.

    17033 Hershey

    United States

Organization profile

Organization profile

Penn State College of Medicine's Department of Neurosurgery is dedicated to providing the highest quality neurosurgical care possible. The department offers a range of state-of-the-art care to referring physicians and their patients, including Gamma Knife radiosurgery, deep brain stimulation, neurotrauma and critical care, neurosurgical oncology, pediatric neurosurgery and more.

The department aims to provide the highest quality, most state-of-the-art, most patient-centered care possible for a number of conditions, including brain, spine and peripheral nerve tumors; concussion; epilepsy; movement disorders; stroke and brain hemorrhage; and traumatic brain, spine and nerve injuries.

As part of its commitment to innovation in the practice of neurosurgery, the department places a strong emphasis on research in developing the next new treatment for tumors of the nervous system, repairing nerve damage and surgical approaches through clinical and basic science research. This includes clinical trials, clinically-based research, preclinical and translational research.

Meanwhile, the department strives to educate the neurosurgeons of the future through electives for MD students and a comprehensive seven-year, ACGME-accredited neurosurgery residency.

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Collaborations and top research areas from the last five years

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  • 4-Aminopyridine induced hyperpolarizing oscillations in pediatric human epileptic tissue are network-driven potassium currents that are abolished by activation of KCNQ2–5 (Kv7.2-Kv7.5) channels

    Kushner, J. K., Hoffman, P. B., Brzezinski, C. R., O'Neill, B. R., Hankinson, T. C., Wilkinson, C. C., Handler, M. H., Hoeffer, C. A. & Alexander, A. L., Jan 2026, In: Neurobiology of Disease. 218, 107252.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 1: intraoperative recommendations for mapping, monitoring, and decision making

    Gerritsen, J. K. W., Karschnia, P., Bello, L., Hervey-Jumper, S., Young, J. S., Seidel, K., Satoer, D. D., Schnell, O., Parsons, M., Nahed, B. V., Menna, G., Teske, N., Ashkan, K., Barberis, M., Bettegowda, C., Boele, F., Byrne, R. W., Cahill, D. P., Delev, D. & De Witte, E. & 45 others, Drummond, K., Duerinck, J., Dunn, G., Emerson, S., Esquenazi, Y., Freyschlag, C. F., Geurts, M., Grossman, R., Hadjipanayis, C. G., Jensdottir, M., Klimek, M., Lee, C., Maguire, A., Mansouri, A., Markert, J. M., Narita, Y., Olivi, A., Pallud, J., Piil, K., Preusser, M., Quinones-Hinojosa, A., Skjøth-Rasmussen, J., Sabel, M., Senft, C., Short, S., Solheim, O. S., Stummer, W., Szelényi, A., Vik-Mo, E. O., Watts, C., Weller, M., Wen, P., Smith, T. R., Sanai, N., Krieg, S. M., Schucht, P., Broekman, M. L. D., De Vleeschouwer, S., Jakola, A. S., van den Bent, M. J., Chang, S. M., Vogelbaum, M. A., Vincent, A. J. P. E., Tonn, J. C. & Berger, M. S., Jan 2026, In: The Lancet Oncology. 27, 1, p. e11-e23

    Research output: Contribution to journalReview articlepeer-review

  • A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 2: perioperative recommendations for neurological, language, functional, and quality-of-life assessment

    Gerritsen, J. K. W., Karschnia, P., Bello, L., Hervey-Jumper, S., Young, J. S., Seidel, K., Satoer, D. D., Schnell, O., Parsons, M., Nahed, B. V., Menna, G., Teske, N., Ashkan, K., Barberis, M., Bettegowda, C., Boele, F., Byrne, R. W., Cahill, D. P., Delev, D. & De Witte, E. & 45 others, Drummond, K., Duerinck, J., Dunn, G., Emerson, S., Esquenazi, Y., Freyschlag, C. F., Geurts, M., Grossman, R., Hadjipanayis, C. G., Jensdottir, M., Klimek, M., Lee, C., Maguire, A., Mansouri, A., Markert, J. M., Narita, Y., Olivi, A., Pallud, J., Piil, K., Preusser, M., Quinones-Hinojosa, A., Skjøth-Rasmussen, J., Sabel, M., Senft, C., Short, S., Solheim, O. S., Stummer, W., Szelényi, A., Vik-Mo, E. O., Watts, C., Weller, M., Wen, P., Smith, T. R., Sanai, N., Krieg, S. M., Schucht, P., Broekman, M. L. D., De Vleeschouwer, S., Jakola, A. S., van den Bent, M. J., Chang, S. M., Vogelbaum, M. A., Vincent, A. J. P. E., Tonn, J. C. & Berger, M. S., Jan 2026, In: The Lancet Oncology. 27, 1, p. e24-e32

    Research output: Contribution to journalReview articlepeer-review

  • Acoustic emission cascade predicting progression to failure of rock and bone

    Bunger, A. P., Lu, Y., Mustafa, A. & McDowell, M. M., May 2 2026, In: Engineering Fracture Mechanics. 337, 111991.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Acute Opioid Receptor Blockade Restores Vascular Endothelial Growth Factor and Astrocyte Response in db/db Mouse Brain Following Hypoxia-Ischemic Injury

    Kumari, R., Proctor, E. A. & McLaughlin, P., Apr 2026, In: Journal of Neuroscience Research. 104, 4, e70125.

    Research output: Contribution to journalArticlepeer-review

  • A DC-Sensitive Video/ Electrophysiology Monitoring Unit for Long-Term Continuous Study of Seizures and Seizure-Associated Spreading Depolarization in a Rat Model

    Liu, J. & Gluckman, B. J., Jan 2026, In: eNeuro. 13, 1, ENEURO.0057-25.2025.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma

    Landry, A. P., Wang, J. Z., Patil, V., Ajisebutu, A., Gui, C., Yefet, L. S., Ellenbogen, Y., Liu, J., Mamatjan, Y., Wei, Q., Singh, O., Mansouri, S., Ehret, F., Capper, D., Cohen-Gadol, A. A., Tabatabai, G., Tatagiba, M., Behling, F., Barnholtz-Sloan, J. S. & Sloan, A. E. & 139 others, Chambless, L. B., Mansouri, A., Makarenko, S., Yip, S., Tsang, D. S., Gao, A., Aldape, K., Nassiri, F., Zadeh, G., Santarius, T., Selman, W., Couce, M., Sloan, A. E., Brastianos, P. K., Shih, H. A., Linda Bi, W., Huang, R. Y., Wen, P. Y., Walbert, T., Lee, I., Felicella, M., Brodie, C., Malta, T., Castro, A. V. C., Noushmehr, H., Snyder, J., Dimeco, F., Saladino, A., Pollo, B., Schichor, C., Tonn, J. C., Kaufmann, T. J., Lachance, D., Giannini, C., Galanis, E., Raghunathan, A., Hanemann, C. O., Au, K., Goldbrunner, R., Galldiks, N., Timmer, M., Ole Schimdt, N., Herold-Mende, C., Sahm, F., Jungk, C., Jungwirth, G., Von Deimling, A., Jenkinson, M. D., Millward, C. P., Islim, A. I., Drummond, K., Morokoff, A., Tabatabai, G., Behling, F., Renovanz, M., Tatagiba, M., Santacroce, A., La Fougere, C., Schittenhelm, J., Raleigh, D. R., Perry, A., Butowski, N., Westphal, M., Lamszus, K., Ricklefs, F., Mawrin, C., Horbinski, C. M., Ng, H. K., Snuderl, M., Kurz, S., Sulman, E. P., Zada, G., Cohen-Gadol, A., Yip, S., Makarenko, S., Zherebitskiy, V., Hnenny, L., Dunn, I. F., Moliterno, J., McDermott, M. W., Vogelbaum, M., Javadpour, M., Fountain, D., Mathiesen, T. I., Aldape, K., Barnholtz-Sloan, J., Pathmanaban, O., Boutros, P. C., Alkividias, T., Fountas, K. N., Walsh, K. M., Short, S. C., Carvalho, B., Maas, S. L. N., Bos, E. M., Dincer, A., Kurz, S., Passlack, P., Deng, M., Ehret, F., Mehta, M. P., Odia, Y., Everson, R., Balogun, J. A., Lopez, C., Calabrese, E., Karschnia, P., Teske, N., Fariselli, L., Greve, T., Arvaniti, C., Benjamin, C., Ivan, M., Jackson, C., Jeyaretna, S., Scartoni, D., Amelio, D., Palmer, J., Ivanidze, J., Ostrom, Q., Trung Kien, D., Youngblood, M., Millareschavez, M., Althgafi, M., Emerson, S., Weller, M., Lerhun, E., Martínez-Pérez, R., Smee, R., Mukherjee, R., Cervio, A., Turner, C., Muirhead, W., Molina, E. S., Julius, V., Chen, J., Karmur, B., Mrugala, M. & Neth, B., Feb 1 2026, In: Neuro-oncology. 28, 2, p. 430-439 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A perspective on CO2 gas sensing — from environments to the skin interface

    Biswas, M. A. S., Geronimo, A. & Cheng, H., Jul 2026, In: Journal of Materiomics. 12, 4, 101228.

    Research output: Contribution to journalComment/debatepeer-review

    Open Access
  • A Rating Scale for Obtaining Specific, Actionable Evaluations of Nasolabial Aesthetics after Unilateral Cleft Lip Repair

    Sitzman, T. J., Samson, T. D., Tse, R. W., Matic, D. B., Fisher, D. M., Beals, S. P., Allori, A. C., Marcus, J. R., Bezuhly, M. & Hanna, H., May 1 2026, In: Plastic and reconstructive surgery. 157, 5, p. 891-898 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Aspiration-assisted bioprinting of spheroids

    Kim, M. H. & Ozbolat, I. T., Apr 2026, In: Nature Protocols. 21, 4, p. 1325-1373 49 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access