Research output per year
Research output per year
Organization profile
Organization profile
The Department of Pharmacology at Penn State College of Medicine is dedicated to teaching and research in the biomedical sciences. Its missions are to provide high-quality training of the next generation of scientists and physicians and to develop new diagnostic tests, medicines and delivery systems.
At its home in Hershey, Pa., the Department of Pharmacology occupies 20,000 square feet of state-of-the-art laboratory space in the Hershey Center for Applied Research, Penn State Cancer Institute and Penn State Institute for Personalized Medicine.
Research ranges from cell and molecular studies of cancer, to biochemical/pharmacological investigation of nervous system function, to whole-animal studies of drug development.
As educational leaders in their fields, departmental faculty are involved in medical, graduate and allied health instruction and training.
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Dive into the research topics where Department of Pharmacology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
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Profiles
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Alfredo Bellon, MD, PhD
- Department of Psychiatry and Behavioral Health - Assistant Professor
- Division of Adult Inpatient Services (Pennsylvania Psychiatric Institute)
- Department of Pharmacology - Assistant Professor
- Penn State Neuroscience Institute
Person: Academic
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Anthony Bonavia, MD
- Department of Anesthesiology and Perioperative Medicine - Professor
- Division of Critical Care Anesthesia
- Department of Pharmacology - Professor
Person: Academic
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Keith Cheng, MD, PhD
- Department of Pathology and Laboratory Medicine - Distinguished Professor
- Division of Experimental Pathology
- Department of Biochemistry and Molecular Biology - Distinguished Professor
- Department of Pharmacology - Distinguished Professor
- Penn State Cancer Institute
- Huck Institutes of the Life Sciences
- Institute for Computational and Data Sciences (ICDS)
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Matthew Coates, MD, PhD
- Department of Medicine - Peter and Marshia Carlino Professor
- Division of Gastroenterology and Hepatology - Director of Research
- Department of Pharmacology - Professor
- Center for Cannabis and Natural Product Pharmaceuticals (CCNPP)
Person: Academic
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Zheng-Ming Ding, MD, MS, PhD
- Department of Anesthesiology and Perioperative Medicine - Associate Professor
- Department of Pharmacology - Associate Professor
Person: Academic
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Nikolay Dokholyan, PhD, MS
- Department of Pharmacology - G. Thomas Passananti Professor and Vice Chair for Research
- Department of Biochemistry and Molecular Biology - Professor
- Penn State Clinical and Translational Science Institute (CTSI) - Associate Director
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
- Penn State Neuroscience Institute
- Center for Cannabis and Natural Product Pharmaceuticals (CCNPP)
Person: Academic
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Sinisa Dovat, PhD, MD
- Department of Pediatrics - Professor and Vice Chair for Basic Science Research
- Division of Hematology and Oncology
- Department of Biochemistry and Molecular Biology - Professor
- Department of Pharmacology - Professor
- Penn State Cancer Institute
- Penn State Neuroscience Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
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John Ellis, PhD
- Department of Psychiatry and Behavioral Health - Professor
- Department of Pharmacology - Professor
- Penn State Neuroscience Institute
Person: Academic
Research output
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2-Deoxyglucose and hydroxychloroquine HPLC-MS–MS analytical methods and pharmacokinetic interactions after oral co-administration in male rats
Sun, D., Kim, S., Karelia, D., Deng, Y., Jiang, C. & Junxuan, L., Feb 2024, In: Pharmacology Research and Perspectives. 12, 1, e1173.Research output: Contribution to journal › Article › peer-review
Open Access -
Activity of DNA polymerase κ across the genome in human fibroblasts
Torres, M. C., Rebok, A., Sun, D. & Spratt, T. E., Jul 9 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 28, e2403130121.Research output: Contribution to journal › Article › peer-review
Open Access -
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes
Paudel, B. B., Tan, S. F., Fox, T. E., Ung, J., Golla, U., Shaw, J. J. P., Dunton, W., Lee, I., Fares, W. A., Patel, S., Sharma, A., Viny, A. D., Barth, B. M., Tallman, M. S., Cabot, M., Garrett-Bakelman, F. E., Levine, R. L., Kester, M., Feith, D. J. & Claxton, D. & 2 others, , Mar 12 2024, In: Blood Advances. 8, 5, p. 1137-1142 6 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Air Pollutants and Risk of Parkinson’s Disease among Women in the Sister Study
Cao, Z., Yuan, Y., White, A. J., Li, C., Luo, Z., D’aloisio, A. A., Huang, X., Kaufman, J. D., Sandler, D. P. & Chen, H., Jan 2024, In: Environmental health perspectives. 132, 1, 017001.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Altering phosphorylation in cancer through PP2A modifiers
Johnson, H., Narayan, S. & Sharma, A. K., Dec 2024, In: Cancer Cell International. 24, 1, 11.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Anticoagulant, Antiplatelet, & Fibrinolytic Medications
Kocis, P. T., Apr 24 2024, Brody's Human Pharmacology. 7th ed. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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Antinociceptive Effects of Cannabichromene (CBC) in Mice: Insights from von Frey, Tail-Flick, Formalin, and Acetone Tests
Raup-Konsavage, W. M., Sepulveda, D. E., Wang, J., Dokholyan, N. V., Vrana, K. E. & Graziane, N. M., Jan 2024, In: Biomedicines. 12, 1, 83.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2
Vishweshwaraiah, Y. L., Hnath, B., Wang, J., Chandler, M., Mukherjee, A., Yennawar, N. H., Booker, S. J., Afonin, K. A. & Dokholyan, N. V., May 20 2024, In: ACS Applied Bio Materials. 7, 5, p. 3238-3246 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Application of Quantum Tensor Networks for Protein Classification
Kundu, D., Ghosh, A., Ekambaram, S., Wang, J., Dokholyan, N. & Ghosh, S., Jun 12 2024, GLSVLSI 2024 - Proceedings of the Great Lakes Symposium on VLSI 2024. Association for Computing Machinery, p. 132-137 6 p. (Proceedings of the ACM Great Lakes Symposium on VLSI, GLSVLSI).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open Access -
Bile salt hydrolase catalyses formation of amine-conjugated bile acids
Rimal, B., Collins, S. L., Tanes, C. E., Rocha, E. R., Granda, M. A., Solanki, S., Hoque, N. J., Gentry, E. C., Koo, I., Reilly, E. R., Hao, F., Paudel, D., Singh, V., Yan, T., Kim, M. S., Bittinger, K., Zackular, J. P., Krausz, K. W., Desai, D. & Amin, S. & 10 others, , Feb 22 2024, In: Nature. 626, 8000, p. 859-863 5 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations
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Discovery of functionally selective dopamine ligands for age-related cognitive decline
Yang, Y. (PI), Dokholyan, N. (CoPI) & Mailman, R. (CoPI)
6/1/24 → 5/31/25
Project: Research project
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Use of a GLP-1 Agonist to Treat Opioid Use Disorder in Rats and Man
Grigson-Kennedy, P. (PI), Nyland, J. (CoPI), Bunce, S. (CoPI) & Brick, T. R. (CoPI)
NATIONAL INSTITUTE ON DRUG ABUSE
5/1/24 → 4/30/25
Project: Research project
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Penn State TCORS: Tobacco Product Composition Effects on Toxicity and Addiction
Muscat, J. (PI), Hobkirk, A. (CoPI), Sun, D. (CoPI), Richie, J. (CoPI), Foulds, J. (CoPI), Liao, J. (CoPI) & Spratt, T. (CoPI)
NATIONAL INSTITUTE ON DRUG ABUSE
9/30/23 → 8/31/25
Project: Research project
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Biomarker and Analytical Chemistry Core
Richie, J. (PI) & Sun, D. (PI)
NATIONAL INSTITUTE ON DRUG ABUSE
9/30/23 → 8/31/25
Project: Research project
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Medical Scientist Training Program
Levenson, R. (PI)
National Institute of General Medical Sciences
7/1/23 → 6/30/25
Project: Research project
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FET:Medium: Drug discovery using quantum machine learning
Dokholyan, N. (CoPI) & Ghosh, S. (PI)
10/1/22 → 9/30/26
Project: Research project
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Penn State Research training in Oncology and Medicine to Inspire Student Engagement (PROMISE)
Eckert, K. (PI) & Matters, G. (CoPI)
9/1/22 → 8/31/25
Project: Research project
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Impaired Vasoreactivity, Sleep Degradation, and Impaired Clearance in the APOE4 Brain
Proctor, E. A. (PI), Gluckman, B. (CoPI) & Drew, P. J. (CoPI)
7/15/22 → 3/31/27
Project: Research project
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Targeting AR and AR-Variants in Castration-Resistant Prostate Cancer
Damodaran, C. (PI), Sharma, A. A. K. (CoPI) & Sharma, A. (CoPI)
2/1/21 → 1/31/25
Project: Research project
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From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics
Cheng, K. (Speaker), Ding, Y. (Speaker), Katz, S. (Speaker), Lin, A. (Speaker), van Rossum, D. (Speaker) & Vanselow, D. (Speaker)
Sep 27 2017Activity: Talk types › Oral presentation
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Motivations and Potential for a 3D Image Informatics for Histopathology (Panel Discussion)
Cheng, K. (Speaker)
Nov 4 2017Activity: Talk types › Oral presentation
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Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish
Cheng, K. (Speaker), Ding, Y. (Speaker), Lin, A. (Speaker), Yakovlev, M. (Speaker), Vanselow, D. (Speaker), Xin, X. (Speaker), Katz, S. (Speaker), Vanselow, D. (Speaker) & La Riviere, P. (Speaker)
Jul 5 2017Activity: Talk types › Oral presentation
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Public Workshop on Warfarin Point-of-Care Testing
Kocis, P. (Speaker)
Mar 2016Activity: Talk types › Invited talk
Prizes
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Career Citation Milestone Award - D (500) Club
Broach, J. (Recipient), Coates, M. (Recipient), Duffy, C. (Recipient), Gardner, A. (Recipient), Gill, D. (Recipient), Helm, K. (Recipient), Kimball, S. (Recipient), Leslie, D. (Recipient), Lipton, A. (Recipient), Ma, T. (Recipient), Naccarelli, G. (Recipient), Schmitz, K. (Recipient), Siedlecki, C. (Recipient), Stoute, J. (Recipient), Tombran-Tink, J. (Recipient) & Wang, H.-G. (Recipient), 2020
Prize
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Career Citation Milestone Award - D (500) Club
Barber, A. (Recipient), Belani, C. (Recipient), Bixler, E. (Recipient), Eslinger, P. (Recipient), Imamura, Y. (Recipient), Legro, R. (Recipient), Mailman, R. (Recipient), Schiff, S. (Recipient), Vgontzas, A. (Recipient) & Wang, H.-G. (Recipient), 2019
Prize
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Career Citation Milestone Award - D (500) Club
Bixler, E. (Recipient) & Cheng, K. (Recipient), 2016
Prize
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Career Citation Milestone Award - D (500) Club
Vgontzas, A. (Recipient) & Wang, H.-G. (Recipient), 2017
Prize
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Career Citation Milestone Award - M (1000) Club
Carrel, L. (Recipient), Cheng, K. (Recipient) & Chin, T. (Recipient), 2020
Prize