Research output per year
Research output per year
Organization profile
Organization profile
The Department of Pharmacology at Penn State College of Medicine is dedicated to teaching and research in the biomedical sciences. Its missions are to provide high-quality training of the next generation of scientists and physicians and to develop new diagnostic tests, medicines and delivery systems.
At its home in Hershey, Pa., the Department of Pharmacology occupies 20,000 square feet of state-of-the-art laboratory space in the Hershey Center for Applied Research, Penn State Cancer Institute and Penn State Institute for Personalized Medicine.
Research ranges from cell and molecular studies of cancer, to biochemical/pharmacological investigation of nervous system function, to whole-animal studies of drug development.
As educational leaders in their fields, departmental faculty are involved in medical, graduate and allied health instruction and training.
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Dive into the research topics where Department of Pharmacology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
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Profiles
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Alfredo Bellon, MD, PhD
- Department of Psychiatry and Behavioral Health - Assistant Professor
- Division of Adult Inpatient Services (Pennsylvania Psychiatric Institute)
- Department of Pharmacology - Assistant Professor
- Penn State Neuroscience Institute
Person: Academic
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Cheston Berlin, MD
- Department of Pediatrics - University Professor of Pediatrics (Primary Care)
- Department of Pharmacology - Professor
Person: Academic
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Anthony Bonavia, MD
- Department of Anesthesiology and Perioperative Medicine - Associate Professor
- Division of Critical Care Anesthesia
- Department of Pharmacology - Associate Professor
Person: Academic
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Nurgul Carkaci-Salli, PhD
- Department of Pharmacology - Assistant Professor
- Penn State Neuroscience Institute
Person: Academic
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Keith Cheng, MD, PhD
- Department of Pathology and Laboratory Medicine - Distinguished Professor
- Division of Experimental Pathology
- Department of Biochemistry and Molecular Biology - Distinguished Professor
- Department of Pharmacology - Distinguished Professor
- Penn State Cancer Institute
- Huck Institutes of the Life Sciences
- Institute for Computational and Data Sciences (ICDS)
- Cancer Institute, Next-Generation Therapies
Person: Academic
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Matthew Coates, MD, PhD
- Department of Medicine - Associate Professor
- Division of Gastroenterology and Hepatology - Director of Research
- Department of Pharmacology - Associate Professor
Person: Academic
Research output
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Abdominal pain is associated with an increased risk of future healthcare resource utilization in inflammatory bowel disease
Zubrzycka, I., Bogale, K., Stuart, A., Cesaire, M., Walter, V., Dalessio, S., Tinsley, A., Williams, E., Clarke, K. & Coates, M. D., Dec 2023, In: International Journal of Colorectal Disease. 38, 1, 213.Research output: Contribution to journal › Article › peer-review
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Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice
Zhu, X., Liu, Q., Patterson, A. D., Sharma, A. K., Amin, S. G., Cohen, S. M., Gonzalez, F. J. & Peters, J. M., Aug 2023, In: Metabolites. 13, 8, 936.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
Qian, F., Nettleford, S. K., Zhou, J., Arner, B. E., Hall, M. A., Sharma, A., Annageldiyev, C., Rossi, R. M., Tukaramrao, D. B., Sarkar, D., Hegde, S., Gandhi, U. H., Finch, E. R., Goodfield, L., Quickel, M. D., Claxton, D. F., Paulson, R. F. & Prabhu, K. S., Jul 25 2023, In: Cell Reports. 42, 7, 112794.Research output: Contribution to journal › Article › peer-review
Open Access -
Adaptations in Nucleus Accumbens Neuron Subtypes Mediate Negative Affective Behaviors in Fentanyl Abstinence
Fox, M. E., Wulff, A. B., Franco, D., Choi, E. Y., Calarco, C. A., Engeln, M., Turner, M. D., Chandra, R., Rhodes, V. M., Thompson, S. M., Ament, S. A. & Lobo, M. K., Mar 15 2023, In: Biological Psychiatry. 93, 6, p. 489-501 13 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Adolescent alcohol disrupts development of noradrenergic neurons in the nucleus of the tractus solitarius and enhances stress behaviors in adulthood in mice in a sex specific manner
Aguilar, L. A., Coker, C. R., McCullers, Z., Evans, A., Showemimo, O., Melkumyan, M., Keller, B. N., Snyder, A. E., Bingaman, S. S., Randall, P. A., Hajnal, A., Browning, K. N., Arnold, A. & Silberman, Y., Dec 15 2023, In: Addiction Neuroscience. 9, 100132.Research output: Contribution to journal › Article › peer-review
Open Access -
Alcohol, nicotine, and COVID-19: A retrospective study of health outcomes in central Pennsylvania
Xu, K. L. & Randall, P. A., Jan 2023, In: Brain Research Bulletin. 192, p. 175-183 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Allosteric inactivation of an engineered optogenetic GTPase
Jain, A., Dokholyan, N. V. & Lee, A. L., Apr 4 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2219254120.Research output: Contribution to journal › Article › peer-review
Open Access -
An engineered N-acyltransferase-LOV2 domain fusion protein enables light-inducible allosteric control of enzymatic activity
Reynolds, J. A., Vishweshwaraiah, Y. L., Chirasani, V. R., Pritchard, J. R. & Dokholyan, N. V., Apr 2023, In: Journal of Biological Chemistry. 299, 4, 103069.Research output: Contribution to journal › Article › peer-review
Open Access -
A noncommutative combinatorial protein logic circuit controls cell orientation in nanoenvironments
Chen, J., Vishweshwaraiah, Y. L., Mailman, R. B., Tabdanov, E. D. & Dokholyan, N. V., May 2023, In: Science Advances. 9, 21, eadg1062.Research output: Contribution to journal › Article › peer-review
Open Access -
A phase II trial of nifurtimox combined with topotecan and cyclophosphamide for refractory or relapsed neuroblastoma and medulloblastoma
Eslin, D., Zage, P. E., Bergendahl, G., Lewis, E., Roberts, W., Kraveka, J., Mitchell, D., Isakoff, M. S., Rawwas, J., Wada, R. K., Fluchel, M., Brown, V. I., Ginn, K., Higgins, T., BeeravallyNagulapally, A., Dykema, K., Hanna, G., Ferguson, W. & Saulnier Sholler, G. L., Sep 1 2023, In: International Journal of Cancer. 153, 5, p. 1026-1034 9 p.Research output: Contribution to journal › Article › peer-review
Open Access
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AI-based Mapping of Complex Cannabis Extracts in Pain Pathways
National Center for Complementary and Integrative Health
2/14/23 → 11/30/23
Project: Research project
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Discovery of functionally selective dopamine ligands for age-related cognitive decline
Yang, Y., Dokholyan, N. & Mailman, R.
6/1/21 → 5/31/24
Project: Research project
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Targeting AR and AR-Variants in Castration-Resistant Prostate Cancer
Damodaran, C., Sharma, A. A. K. & Sharma, A.
2/1/21 → 1/31/24
Project: Research project
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Role played by Acid Ion Sensing Channels in Peripheral Artery Disease
Kaufman, M. & Ruiz-Velasco, V.
National Heart, Lung, and Blood Institute
12/15/20 → 11/30/23
Project: Research project
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Electronic Cigarette-derived Oxidants and their Impact on Lung Cancer Development
Foulds, J., Richie, J. & Bitzer, Z.
6/5/20 → 5/31/24
Project: Research project
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Targeting Aldehyde Dehydrogenase for Cancer Prevention
Robertson, G., Amin, S. & Schell, T.
4/15/20 → 3/31/24
Project: Research project
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The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease
National Institute of Diabetes and Digestive and Kidney Diseases
4/10/20 → 1/31/24
Project: Research project
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Nanoscale programing of cellular and physiological phenotypes
National Institute of General Medical Sciences
1/1/20 → 12/31/23
Project: Research project
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Motivations and Potential for a 3D Image Informatics for Histopathology (Panel Discussion)
Keith Cheng (Speaker)
Nov 4 2017Activity: Talk types › Oral presentation
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From Morphology to Math: Using whole zebrafish to create the engineering and computational infrastructure for Microanatomic Phenomics
Keith Cheng (Speaker), Y Ding (Speaker), SR Katz (Speaker), AY Lin (Speaker), D van Rossum (Speaker) & D Vanselow (Speaker)
Sep 27 2017Activity: Talk types › Oral presentation
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Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish
Keith Cheng (Speaker), Y Ding (Speaker), AY Lin (Speaker), M Yakovlev (Speaker), D Vanselow (Speaker), X Xin (Speaker), S Katz (Speaker), D Vanselow (Speaker) & PJ La Riviere (Speaker)
Jul 5 2017Activity: Talk types › Oral presentation
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Public Workshop on Warfarin Point-of-Care Testing
Paul Kocis (Speaker)
Mar 2016Activity: Talk types › Invited talk
Prizes
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Career Citation Milestone Award - D (500) Club
Broach, James (Recipient), Coates, Matthew (Recipient), Duffy, Charles (Recipient), Gardner, Andrew (Recipient), Gill, Donald (Recipient), Helm, Klaus (Recipient), Kimball, Scot (Recipient), Leslie, Douglas (Recipient), Lipton, Allan (Recipient), Ma, Thomas (Recipient), Naccarelli, Gerald (Recipient), Schmitz, Kathryn (Recipient), Siedlecki, Christopher (Recipient), Stoute, Jose (Recipient), Tombran-Tink, Joyce (Recipient) & Wang, Hong-Gang (Recipient), 2020
Prize
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Career Citation Milestone Award - D (500) Club
Vgontzas, Alexandros (Recipient) & Wang, Hong-Gang (Recipient), 2017
Prize
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Career Citation Milestone Award - D (500) Club
Barber, Alistair (Recipient), Belani, Chandra (Recipient), Bixler, Edward (Recipient), Eslinger, Paul (Recipient), Imamura, Yuka (Recipient), Legro, Richard (Recipient), Mailman, Richard (Recipient), Schiff, Steven (Recipient), Vgontzas, Alexandros (Recipient) & Wang, Hong-Gang (Recipient), 2019
Prize
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Career Citation Milestone Award - D (500) Club
Bixler, Edward (Recipient) & Cheng, Keith (Recipient), 2016
Prize
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Career Citation Milestone Award - M (1000) Club
Carrel, Laura (Recipient), Cheng, Keith (Recipient) & Chin, Thomas (Recipient), 2020
Prize