Division of Applied Biomedical Engineering

Websitehttps://research.med.psu.edu/departments/surgery/surgery-facilities/

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United States

Organization profile

The Division of Applied Biomedical Engineering, a research division of the Department of Surgery at Penn State College of Medicine, maintains a polymer fabrication lab, system assembly clean room, machine shop, electronics lab, mock loop test lab, mechanical assembly room and computer-aided design room.

Joshua Cysyk, MS, PhD
- Department of Surgery - Associate Professor
- Division of Applied Biomedical Engineering
Person: Academic
20062025
Choon-Sik Jhun, MS, PhD
- Department of Surgery - Associate Professor
- Division of Applied Biomedical Engineering
Person: Academic
20082025
Branka Lukic, MEng, MS
- Department of Surgery - Assistant Professor
- Division of Applied Biomedical Engineering
Person: Academic
20022024
Christopher Siedlecki, MS, PhD
- Department of Surgery - Jane A. Fetter Professor
- Division of Applied Biomedical Engineering
- Biomedical Engineering - Professor
Person: Academic
19942026
William Weiss, MS, PhD
- Department of Surgery - C. McCollister Evarts, MD Professor in Artificial Organs
- Division of Applied Biomedical Engineering - Chief
- Biomedical Engineering - Professor
Person: Academic
19822025
Lichong Xu, MS, PhD
- Department of Surgery - Associate Professor
- Division of Applied Biomedical Engineering
Person: Academic
19992026

10581 Citations
52 h-index
251 Article
38 Conference contribution
19 Chapter
16 Conference article
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Anti-Biofilm Properties of Polyurethane Biomaterials Tethered With Small Molecules via Polyethylene Glycol Linker
Liu, J., Chen, C., Booth, J. L., Lanza, M., Sun, D., Allcock, H. R., Siedlecki, C. A. & Xu, L. C., Apr 2026, In: Journal of Biomedical Materials Research - Part A. 114, 4, e70069.
Research output: Contribution to journal › Article › peer-review

Open Access
Bilayer vascular grafts separately composited with nitric oxide-releasing keratin conjugates and hydrogen sulfide-releasing heparin conjugates
Wang, C., Liang, F., Wang, L., Sun, Y., Xu, L. C., Zhang, J., Pan, Y., Shen, J., Yin, M. & Yuan, J., May 2025, In: International Journal of Biological Macromolecules. 307, 141887.
Research output: Contribution to journal › Article › peer-review
6 Link opens in a new tab Scopus citations
Competitive adsorption and functional activity of fibrinogen on polyurethane biomaterials surfaces
Xu, L. C. & Siedlecki, C. A., Jul 1 2025, In: Biointerphases. 20, 4, 041007.
Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations
GPVI-mediated thrombus stabilization of shear-induced platelet aggregates in a microfluidic stenosis
Watson, C. T., Siedlecki, C. A. & Manning, K. B., Jan 7 2025, In: Biophysical journal. 124, 1, p. 158-171 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
8 Link opens in a new tab Scopus citations
In Vitro and In Vivo biocompatibility study of fluorinated polyphosphazene coatings for blood-contacting medical devices
Gregorits, B. M., Wu, Y., Chen, C., Yeager, E., Parker, M. C., Martinez, I., Lancaster, M. L., Schmiedt, C., Handa, H., Allcock, H. R., Siedlecki, C. A. & Xu, L. C., Sep 1 2025, In: Acta Biomaterialia. 203, p. 346-357 12 p.
Research output: Contribution to journal › Article › peer-review
3 Link opens in a new tab Scopus citations
Preliminary Long-Term Biocompatibility Assessment of Penn State University Child Pump
Jhun, C. S., Clark, J. B., Gentile, J. I., Cysyk, J. P., Bohnenberger, K., Scheib, C. M., Izer, J., Lanza, M., Tillinger, M., Flory, H., Yeager, E., Weiss, W. J. & Rosenberg, G., Sep 1 2025, In: ASAIO Journal. 71, 9, p. e126-e129
Research output: Contribution to journal › Article › peer-review
Two Peas in a Pod: Retroviral RNA Dimers Organize Gag–RNA Nanoclusters with Novel Biophysical Properties
Lambert, G. S., Siedlecki, C. A. & Parent, L. J., Jun 2025, In: International journal of molecular sciences. 26, 12, 5679.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Link opens in a new tab Scopus citations
Development of the PSU Child Pump
Scheib, C., Newswanger, R., Cysyk, J., Bohnenberger, K., Lukic, B., Xu, L., Yeager, E., Bletcher, K., Leibich, P., Jackson, Q., Flory, H., Tillinger, M., Weiss, W., Rosenberg, G. & Jhun, C. S., Oct 1 2024, In: ASAIO Journal. 70, 10, p. 892-897 6 p.
Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations
Fluid Dynamic Study of the Penn State Pediatric Total Artificial Heart
Kubicki, C., Raich, E., Selinsky, P., Ponnaluri, S., Weiss, W. & Manning, K. B., Oct 1 2024, In: Journal of Biomechanical Engineering. 146, 10, 101007.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Link opens in a new tab Scopus citations
FXII contact activation products have an inhibitory effect on αFXIIa
Xu, L. C. & Siedlecki, C. A., Aug 2024, In: Journal of Biomedical Materials Research - Part A. 112, 8, p. 1213-1223 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access

4 Active
11 Finished

Multimeric Structural Degradation of vWF in Turbulent Flows
Jhun, C.-S. (PI)
National Heart, Lung, and Blood Institute
1/5/23 → 11/30/26
Project: Research project
An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation
Weiss, W. (PI)
U.S. Army
9/30/20 → …
Project: Research project
An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation
Weiss, W. (PI)
Congressionally Directed Medical Research Programs
1/1/19 → …
Project: Research project
An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation
Weiss, W. (PI)
U.S. Army
9/15/16 → …
Project: Research project
An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation
Weiss, W. (PI)
Congressionally Directed Medical Research Programs
9/15/16 → 9/14/19
Project: Research project
Transcutaneous Energy Transmission System for Fully Implantable VADs
Mccabe, A. R. (PI) & Weiss, W. (CoPI)
National Heart, Lung, and Blood Institute
2/15/14 → 4/30/17
Project: Research project
Development of a Miniature Hydrodynamically Suspended Intrathoracic Tesla Pump
Nazarian, R. (PI) & Rosenberg, G. (CoPI)
National Heart, Lung, and Blood Institute
9/1/12 → 8/31/14
Project: Research project
Transcutaneous Energy Transmission System for Fully Implantable VADs
Nazarian, R. (PI) & Weiss, W. (CoPI)
National Heart, Lung, and Blood Institute
7/2/12 → 12/31/12
Project: Research project
Development of an Infant VAD System for Long Term Uni- and Bi-ventricular Support
Nazarian, R. (PI) & Weiss, W. (CoPI)
National Heart, Lung, and Blood Institute
7/15/11 → 7/31/14
Project: Research project
Development of a Miniature Hydrodynamically Suspended Intrathoracic Tesla Pump
Nazarian, R. (PI) & Rosenberg, G. (CoPI)
National Heart, Lung, and Blood Institute
7/1/11 → 6/30/12
Project: Research project

Career Citation Milestone Award - D (500) Club
Broach, J. (Recipient), Coates, M. (Recipient), Duffy, C. (Recipient), Gardner, A. (Recipient), Gill, D. (Recipient), Helm, K. (Recipient), Kimball, S. (Recipient), Leslie, D. (Recipient), Lipton, A. (Recipient), Ma, T. (Recipient), Naccarelli, G. (Recipient), Schmitz, K. (Recipient), Siedlecki, C. (Recipient), Stoute, J. (Recipient), Tombran-Tink, J. (Recipient) & Wang, H.-G. (Recipient), 2020
Prize

Division of Applied Biomedical Engineering

Organization profile

Organization profile

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Joshua Cysyk, MS, PhD

Choon-Sik Jhun, MS, PhD

Branka Lukic, MEng, MS

Christopher Siedlecki, MS, PhD

William Weiss, MS, PhD

Lichong Xu, MS, PhD

Anti-Biofilm Properties of Polyurethane Biomaterials Tethered With Small Molecules via Polyethylene Glycol Linker

Bilayer vascular grafts separately composited with nitric oxide-releasing keratin conjugates and hydrogen sulfide-releasing heparin conjugates

Competitive adsorption and functional activity of fibrinogen on polyurethane biomaterials surfaces

GPVI-mediated thrombus stabilization of shear-induced platelet aggregates in a microfluidic stenosis

In Vitro and In Vivo biocompatibility study of fluorinated polyphosphazene coatings for blood-contacting medical devices

Preliminary Long-Term Biocompatibility Assessment of Penn State University Child Pump

Two Peas in a Pod: Retroviral RNA Dimers Organize Gag–RNA Nanoclusters with Novel Biophysical Properties

Development of the PSU Child Pump

Fluid Dynamic Study of the Penn State Pediatric Total Artificial Heart

FXII contact activation products have an inhibitory effect on αFXIIa

Multimeric Structural Degradation of vWF in Turbulent Flows

An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation

An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation

An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation

An Implantable Blood Pump for Adult Congenital Heart Disease Patients with a Failed Fontan Circulation

Transcutaneous Energy Transmission System for Fully Implantable VADs

Development of a Miniature Hydrodynamically Suspended Intrathoracic Tesla Pump

Transcutaneous Energy Transmission System for Fully Implantable VADs

Development of an Infant VAD System for Long Term Uni- and Bi-ventricular Support

Development of a Miniature Hydrodynamically Suspended Intrathoracic Tesla Pump

Career Citation Milestone Award - D (500) Club

Division of Applied Biomedical Engineering

Organization profile

Organization profile

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Projects

Prizes