Organization profile
Organization profile
The Division of Colon and Rectal Surgery in the Department of Surgery at Penn State College of Medicine provides advanced and effective medical care, including state-of-the-art diagnostic capabilities, the latest drug therapies and leading-edge surgical techniques for benign and malignant colorectal disease.
From treating cancer and inflammatory bowel disease to performing advanced diagnostics and robotic surgery, the colorectal team is one of the largest and most experienced in Pennsylvania.
The division has an active clinical and basic science research program, including a research laboratory that has studied IBD for nearly 20 years.
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Collaborations and top research areas from the last five years
Profiles
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Walter Koltun, MD
- Department of Surgery - Peter and Marshia Carlino Chair in Inflammatory Bowel Disease
- Division of Colon and Rectal Surgery
- Penn State Cancer Institute
Person: Academic
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Audrey Kulaylat, MD, MS
- Department of Surgery - Carlino Family Early Career Professor in Inflammatory Bowel Disease
- Division of Colon and Rectal Surgery
Person: Academic
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Jeffrey Scow, MD
- Department of Surgery - Associate Professor
- Division of Colon and Rectal Surgery - Interim Chief
- Penn State Cancer Institute
Person: Academic
Research output
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Anastomotic Leak Following Colorectal Surgery
Ziegler, O. & Kulaylat, A. S., Jan 1 2026, In: Clinics in Colon and Rectal Surgery. 39, 1, p. 24-36 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Apixaban Versus Enoxaparin for Venous Thromboembolism Prophylaxis in Colorectal Surgery
Ziegler, O., Greene, A. C., Waldron, O., Lynn, P. B., Kulaylat, A. S., Scow, J. S., Koltun, W. A. & Deutsch, M. J., Jul 2025, In: Journal of Surgical Research. 311, p. 332-338 7 p.Research output: Contribution to journal › Article › peer-review
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Exposure to advanced therapies and risk of surgery in Crohn’s disease
Mankarious, M. M., Dijoseph, K., Greene, A. C., Schaefer, E. W., Clarke, K., Deutsch, M. J., Scow, J. S., Kulaylat, A. N. & Kulaylat, A. S., Aug 2025, In: Surgical endoscopy. 39, 8, p. 5367-5375 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Improvement in Functional Outcomes Following Ileal Pouch-Anal Anastomosis: Results from the United States Ileal Pouch-Anal Anastomosis Study
Zuckerman, J., de Buck van Overstraeten, A., Melmed, G. Y., Mustain, W. C., Scow, J. S., Otterson, M. F., Ogilvie, J. W., Bordeianou, L., Brar, M. S., Wells, K. O., Ovsepyan, G., Mirocha, J. M., Holubar, S. D., Wexner, S. D., Hyman, N. H., Fleshner, P. & Zaghiyan, K., Nov 2025, In: Diseases of the colon and rectum. 68, 11, p. 1315-1326 12 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations -
Letter: Are Antispasmodics Truly Ineffective in IBD? Considerations on Nuanced Interpretation and Stratified Analysis. Authors' Reply
Khunsriraksakul, C., Ziegler, O., Liu, D., Kulaylat, A. S. & Coates, M. D., Jul 2025, In: Alimentary Pharmacology and Therapeutics. 62, 1, p. 99-100 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Loss of STIM2, but not of STIM1, drives colorectal cancer metastasis through metabolic reprogramming and the ATF4 ER stress pathway
Pathak, T., Benson, J. C., Johnson, M. T., Xin, P., Abdelnaby, A. E., Walter, V., Koltun, W. A., Yochum, G. S., Hempel, N. & Trebak, M., Jun 24 2025, In: Science signaling. 18, 892, eads6550.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
Metatranscriptomic analysis of colonic mucosal samples exploring the functional role of active microbial consortia in complicated diverticulitis
McMullen, B. N., See, J. C., Baker, S., Wright, J. R., Anderson, S. L. C., Yochum, G., Koltun, W., Portolese, A., Jeganathan, N. A. & Lamendella, R., Jul 2025, In: Microbiology Spectrum. 13, 7Research output: Contribution to journal › Article › peer-review
Open Access -
Novel Low-Cost Low-Fidelity Abdominal Wall Simulation is Effective for Surgical Education
Ziegler, O., Greene, A. C., Fiorini, L., Moyer, E. D., Quattrone, M., Jikaria, N., Santos, M. C., Brahmbhatt, R. D. & Kulaylat, A. S., Nov 2025, In: Journal of Surgical Research. 315, p. 79-85 7 p.Research output: Contribution to journal › Article › peer-review
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Outcome variation in the use and duration of antibiotic therapy in patients presenting with acute diverticulitis
Ziegler, O., Schaefer, E. W., Greene, A. C., Moyer, E. D., Delgado, Z., Lynn, P. B., Scow, J. S., Deutsch, M. J. & Kulaylat, A. S., Dec 2025, In: BMC Gastroenterology. 25, 1, 830.Research output: Contribution to journal › Article › peer-review
Open Access -
Proceedings of the American College of Surgeons Surgical Adhesions Improvement Project Summit
Surgical Consortium on Adhesions Research (SCAR) Advisory Group, May 1 2025, In: Journal of the American College of Surgeons. 240, 5, p. 812-819 8 p.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 2 Finished
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A PROPOSAL FOR THE CREATION OF AN INFLAMMATORY BOWEL DISEASE REGISTRY
Ray, C. A. (PI) & Koltun, W. (PI)
National Center for Research Resources
4/1/07 → 3/31/10
Project: Research project
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General Clinical Research Center
Paz, H. H. L. (PI), Boustred, A. M. (CoPI), Ross, A. A. C. (CoPI), Barrett, A. A. M. (CoPI), Momen, A. (CoPI), Ahluwalia, N. (CoPI), Ahsan, N. (CoPI), Vgontzas, A. A. N. (CoPI), Ambrose, A. A. (CoPI), Dunaif, A. A. E. (CoPI), Ouyang, A. (CoPI), Bascom, R. (CoPI), Beard, J. L. (CoPI), Blosser, S. (CoPI), Boehmer, J. (CoPI), Parker, B. B. (CoPI), Campbell, W. W. (CoPI), Miller, C. C. K. (CoPI), Cavanagh, P. R. (CoPI), Dong, C. C. (CoPI), Ray, C. A. (CoPI), Ehmann, C. (CoPI), Flaherty, C. (CoPI), Macneill, C. (CoPI), Consevage, M. (CoPI), Corwin, E. J. (CoPI), Cronin, A. J. (CoPI), Chuang, C. C. H. (CoPI), Torgerson, C. C. S. (CoPI), Daley, J. C. (CoPI), Kirch, D. D. G. (CoPI), Conroy, D. D. E. (CoPI), Han, D. (CoPI), Proctor, D. N. (CoPI), Thiboutot, D. (CoPI), Downs, D. D. S. (CoPI), Erickson, D. D. (CoPI), Eggli, D. F. (CoPI), Ehman, C. (CoPI), Farace, E. (CoPI), Sieverling, E. (CoPI), Spiller, E. E. (CoPI), Vesell, E. S. (CoPI), Burks, E. E. (CoPI), Fitzgerald, E. E. (CoPI), Galka, E. E. (CoPI), Evans, W. J. (CoPI), Evarts, C. M. (CoPI), Eyster, N. M. E. (CoPI), Bixler, E. E. O. (CoPI), Susman, E. E. J. (CoPI), Farrell, P. A. (CoPI), Rosales, F. J. (CoPI), Gardner, T. W. (CoPI), Gaumond, R. (CoPI), Gordon, R. (CoPI), Granger, D. A. (CoPI), Graff, G. (CoPI), Podskalny, G. G. P. (CoPI), Hankey, P. A. (CoPI), Holman, M. J. (CoPI), Holtzclaw, B. J. (CoPI), Harvey, H. (CoPI), Paul, I. I. A. (CoPI), Gilchrist, I. (CoPI), Rodrigues, I. I. (CoPI), Trussel, J. J. (CoPI), Connor, J. J. D. (CoPI), Ulbrecht, J. (CoPI), Ramer, J. (CoPI), Luck, J. J. (CoPI), Cui, J. J. (CoPI), Floros, J. (CoPI), Jones, B. C. (CoPI), Finkelstein, J. J. (CoPI), Joshi, R. (CoPI), Muscat, J. (CoPI), Pawelczyk, J. J. A. (CoPI), Ultman, J. S. (CoPI), Smith, J. J. P. (CoPI), Florian, J. J. (CoPI), Kenney, L. W. (CoPI), Monahan, K. D. (CoPI), Khan, M. (CoPI), Kirwan, J. P. (CoPI), Koch, K. L. (CoPI), Kraemer, W. J. (CoPI), Kulin, H. E. (CoPI), Scott, K. K. (CoPI), Holowatz, L. L. (CoPI), Lallos, C. (CoPI), LaNoue, K. (CoPI), Larsson, L. G. (CoPI), Lathrop, M. (CoPI), Klein, L. L. C. (CoPI), Demers, L. L. M. (CoPI), Rodichok, L. D. (CoPI), Birch, L. L. (CoPI), Xu, L. L. (CoPI), Baker, L. L. B. (CoPI), Lipton, A. (CoPI), Lloyd, T. (CoPI), Loomis, J. L. (CoPI), Stauffer, L. L. A. (CoPI), Thorndyke, L. E. (CoPI), Francis, L. A. (CoPI), Maclean, D. A. (CoPI), Manni, A. (CoPI), Lott, M. E. J. (CoPI), Mastro, A. M. (CoPI), Mccabe, P. (CoPI), McGarrity, T. (CoPI), Pallone, M. N. (CoPI), Miller, B. A. (CoPI), Petit, M. M. A. (CoPI), Mulfinger, L. (CoPI), Latash, M. M. L. (CoPI), Green, M. (CoPI), Pu, M. M. (CoPI), Xiong, N. N. (CoPI), Williams, N. (CoPI), Raja-Khan, N. (CoPI), Thomas, N. N. (CoPI), Ayannusi, O. E. (CoPI), Page, M. J. (CoPI), Mcnulty, P. P. H. (CoPI), Eslinger, P. (CoPI), Kris-Etherton, P. (CoPI), Lee, P. P. A. (CoPI), Phelps, D. (CoPI), Powers, S. K. (CoPI), Pritchard, T. C. (CoPI), Molenaar, P. P. C. (CoPI), Janicki, P. (CoPI), Yang, Q. Q. X. (CoPI), Ramirez-Zea, M. (CoPI), Singareddy, R. R. K. (CoPI), Reynolds, H. (CoPI), Miraliakbari, R. (CoPI), Legro, R. R. S. (CoPI), Cooney, R. (CoPI), Rolls, B. (CoPI), Rolls, B. J. (CoPI), Wilson, R. (CoPI), Jarvis, S. S. (CoPI), West, S. S. G. (CoPI), Shoemaker, N. J. K. (CoPI), Shoemaker, K. J. (CoPI), Leong, S. S. (CoPI), Shriver, M. D. (CoPI), Sinoway, L. I. (CoPI), Ettinger, S. S. (CoPI), Streufert, S. (CoPI), Ridout, S. S. J. (CoPI), Wilson, T. T. R. (CoPI), O'Bryan, T. A. (CoPI), Subramanian, T. T. (CoPI), Hartman, T. J. (CoPI), Loughran, T. T. P. (CoPI), Craig, T. (CoPI), Leuenberger, U. U. A. (CoPI), Imadojemu, V. A. (CoPI), Koltun, W. W. A. (CoPI), Davis, W. W. S. (CoPI), Watterberg, K. L. (CoPI), Flood, W. W. (CoPI), Reeves, W. C. (CoPI), Dodson, W. W. E. (CoPI), Curry, W. (CoPI), Rybka, W. B. (CoPI), Simmons, Z. (CoPI), Challis, J. J. (CoPI), Albaugh, V. L. (CoPI), Aronson, K. R. (CoPI), Belani, C. (CoPI), Betterman, K. (CoPI), Birch, L. L. (CoPI), Cavener, D. R. (CoPI), Claxton, D. (CoPI), Connor, J. D. (CoPI), Cooney, R. (CoPI), Corwin, R. L. (CoPI), Craig, T. J. (CoPI), Cui, J. (CoPI), De Souza, M. J. (CoPI), Dong, C. (CoPI), Elavsky, S. (CoPI), Gao, Z. (CoPI), Giampetro, D. (CoPI), Gill, D. J. (CoPI), Goldenberg, D. N. (CoPI), Graff, G. R. (CoPI), Graham-Engeland, J. E. (CoPI), Green, M. H. (CoPI), Harvey, H. (CoPI), Holowatz, L. (CoPI), Huang, X. (CoPI), Kimchi, E. T. (CoPI), Koltun, W. (CoPI), Kris-Etherton, P. M. (CoPI), Lang, J. C. (CoPI), Latash, M. (CoPI), Lee, P. A. (CoPI), Legro, R. (CoPI), Leuenberger, U. (CoPI), Liao, D. (CoPI), Lohse, B. (CoPI), McBrier, N. M. (CoPI), Monahan, K. D. (CoPI), Paul, I. (CoPI), Paz, H. (CoPI), Proctor, D. N. (CoPI), Ramer, J. (CoPI), Rauh, E. (CoPI), Ray, C. A. (CoPI), Rybka, W. (CoPI), Scalzi, L. V. (CoPI), Sciamanna, C. (CoPI), Scott, K. (CoPI), Selan, J. (CoPI), Simmons, Z. (CoPI), Singareddy, R. K. (CoPI), Skulas-ray, A. (CoPI), Smith, J. P. (CoPI), Ulbrecht, J. S. (CoPI), Vender, R. L. (CoPI), Vgontzas, A. (CoPI), West, S. G. (CoPI), Demers, L. (CoPI), Dunaif, A. (CoPI), Ettinger, S. (CoPI) & Ultman, J. S. (CoPI)
National Center for Research Resources
8/15/95 → 3/31/07
Project: Research project
Prizes
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Dean's Award for Excellence in Teaching
Aprile, B. (Recipient), Aumiller, B. B. (Recipient), Berkey, F. (Recipient), Bonavia, A. (Recipient), Booth, J. (Recipient), Brennan, K. (Recipient), Browning, K. (Recipient), Buchkovich, N. (Recipient), Butt, F. K. (Recipient), Carrel, L. (Recipient), Choe, A. (Recipient), Clarke, S. (Recipient), Coleman, M. (Recipient), Dalke, K. (Recipient), Devaraj, T. (Recipient), Duryea, S. (Recipient), Enama, J. (Recipient), Evey, L. (Recipient), Finch, E. (Recipient), Fischer, M. (Recipient), Gallo, R. (Recipient), Gavigan, P. (Recipient), Ghaffari, G. (Recipient), Go, P. (Recipient), Grana, J. (Recipient), Greensmith, J. (Recipient), Grogan, J. (Recipient), Hajnal, A. (Recipient), Helm, M. (Recipient), Hempel, N. (Recipient), Imamura, F. (Recipient), Jain, R. (Recipient), Jeganathan, N. (Recipient), Kelle, A. (Recipient), Kumar, A. (Recipient), Kwun, H. J. (Recipient), Lang, C. (Recipient), Lutzkanin, A. (Recipient), Martin, K. (Recipient), McGarrity, T. (Recipient), McHale, K. (Recipient), McLaughlin, P. (Recipient), Mormando, C. (Recipient), Nguyen, J. (Recipient), Nickolich, M. (Recipient), Ouyang, T. (Recipient), Pachuski, J. (Recipient), Polimera, H. (Recipient), Potochny, E. (Recipient), Rakszawski, K. L. (Recipient), Reyes, L. (Recipient), Sankoorikal, B.-J. (Recipient), Shantz, L. (Recipient), Singh, M. (Recipient), Songdej, N. (Recipient), Spotts, R. (Recipient), Swigart, A. (Recipient), Varner, M. (Recipient), Verma, N. (Recipient), Walter, V. (Recipient), Wang, C.-Y. (Recipient), Warfield, D. (Recipient), Wilson, M. N. (Recipient) & Hussein, R. (Recipient), 2021
Prize
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Dean's Award for Excellence in Teaching
McAlevy, M. (Recipient), Bonavia, A. (Recipient), Malhotra, A. (Recipient), Weller, G. E. (Recipient), Waning, D. (Recipient), Lanza, M. (Recipient), Ken, K. (Recipient), McCarver, S. (Recipient), Glasser, J. (Recipient), Schooler, J. (Recipient), Lewis, S. (Recipient), Onks, C. (Recipient), Rao, R. (Recipient), Nickolich, S. (Recipient), Helm, L. (Recipient), Critchfield, L. (Recipient), Myers, K. (Recipient), Green, M. (Recipient), Songdej, N. (Recipient), Narayana, S. (Recipient), Razjouyan, H. (Recipient), Duca, N. (Recipient), Casas, R. (Recipient), Cooper, J. (Recipient), Wright, R. (Recipient), Karasinski, A. (Recipient), Probolus, J. A. (Recipient), Madara, J. (Recipient), Guck, D. (Recipient), Ingram, D. (Recipient), De Obaldia, A. (Recipient), Hussein, R. (Recipient), McGillen, B. (Recipient), Chapman, T. (Recipient), Munyon, R. (Recipient), Kinard, S. R. (Recipient), Banks, S. (Recipient), Genao, I. (Recipient), McShane, M. (Recipient), Allie, S. R. (Recipient), Silberman, Y. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Grogan, J. (Recipient), Nguyen, J. (Recipient), Donato, H. (Recipient), Fox, E. (Recipient), Gniady, J. (Recipient), Oladipo, O. (Recipient), Abendroth, C. (Recipient), Keefer, L. (Recipient), Massare, B. (Recipient), Undar, A. (Recipient), Mondal, P. (Recipient), Mainali, G. (Recipient), Jhaveri, P. (Recipient), Freiberg, A. (Recipient), Levenson, R. (Recipient), Mailman, R. (Recipient), Boodoo, R. (Recipient), Francis, A. (Recipient), Hameed, U. (Recipient), Yadav, S. (Recipient), Calo, W. (Recipient), Pinto, C. (Recipient), Cooper, A. (Recipient), Kulaylat, A. (Recipient), Scow, J. (Recipient), Roberts, J. (Recipient), Winder, J. (Recipient), Aminsharifi, A. (Recipient), Adams, N. (Recipient) & van Riggelen, J. (Recipient), 2023
Prize
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Dean’s Award for Excellence in Teaching
Hollins, L. C. (Recipient), Nisnevitch-Savarese, Z. (Recipient), Read, S. (Recipient), Rossi, J. (Recipient), Royo, M. (Recipient), Sarraf, E. (Recipient), Shah, B. (Recipient), Moldovan, G.-L. (Recipient), van Riggelen, J. (Recipient), Shantz, L. (Recipient), Yengo, C. (Recipient), Booth, J. (Recipient), Bates, E. (Recipient), Schuster, A. (Recipient), Clebak, K. (Recipient), Daniels, E. W. (Recipient), Hays, A. (Recipient), Hemerly, N. (Recipient), Thompson, A. (Recipient), George, D. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Acharya, J. (Recipient), De Jesus, S. (Recipient), O'Leary, A. (Recipient), Wright, T. (Recipient), Cantore, W. (Recipient), Pantanelli, S. (Recipient), Millard, R. (Recipient), Updegrove, G. F. (Recipient), Choi, K. (Recipient), Darowish, C. (Recipient), Dooley, A. (Recipient), Hackman, N. (Recipient), Krawiec, C. (Recipient), Oji-Mmuo, C. (Recipient), Ryan, S. (Recipient), Shedlock, A. (Recipient), Tunks, R. (Recipient), Critchfield, L. (Recipient), Bellon, A. (Recipient), Dougherty, K. (Recipient), Lagman, J. (Recipient), Mahgoub, Y. (Recipient), Dreibelbis, T. (Recipient), Richie, J. (Recipient), Wang, L. (Recipient), Methratta, S. (Recipient), Chauvin, N. (Recipient), Deutsch, M. (Recipient), Kulaylat, A. (Recipient), Paulishak, M. (Recipient), Staszak, R. (Recipient) & MacDonald, S. (Recipient), 2022
Prize