Organization profile
Organization profile
The Drug Discovery, Development and Delivery (D4) core offers investigators the ability to test more than 102,000 small compounds for the ability to target an enzyme or other biological target.
The D4 core houses all the necessary instrumentation and robotics used in traditional medium throughput screening (MTS) and is capable of screening both in vitro and cell-based assays.
D4 works with investigators to screen libraries from the core for action against their target of interest, and can also screen novel compounds that researchers have identified for activity against select targets. In addition, researchers are also welcome to utilize the equipment in the D4 core for their projects.
Fingerprint
Collaborations and top research areas from the last five years
Research output
- 11 Citations
- 1 h-index
- 2 Article
-
Cannabinoids as Potential Cancer Therapeutics: The Concentration Conundrum
Carkaci-Salli, N., Raup-Konsavage, W. M., Karelia, D., Sun, D., Jiang, C., Lu, J. & Vrana, K. E., Aug 1 2024, In: Cannabis and Cannabinoid Research. 9, 4, p. e1159-e1169Research output: Contribution to journal › Article › peer-review
10 Link opens in a new tab Scopus citations -
Library Screening and Preliminary Characterization of Synthetic Cannabinoids Against Prostate and Pancreatic Cancer Cell Lines
Karelia, D., Corey, Z., Wang, H., Raup-Konsavage, W. M., Vrana, K. E., Lü, J. & Jiang, C., Apr 1 2024, In: Cannabis and Cannabinoid Research. 9, 2, p. 523-536 14 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations
Equipment
-
COM-D4-Beckman System Gold High-Performance Liquid Chromatograph
Drug Discovery, Development and Delivery CoreEquipment/facility: Equipment
-
COM-D4-Eppendorf epMotion 5070 robot
Drug Discovery, Development and Delivery CoreEquipment/facility: Equipment
-
-
COM-D4-Integra VIAFLOW 96/384 pipette
Drug Discovery, Development and Delivery CoreEquipment/facility: Equipment
-
-
COM-D4-Molecular Devices Flexstation 3 plate reader
Drug Discovery, Development and Delivery CoreEquipment/facility: Equipment
-
COM-D4-Seahorse XFe96 Analyzer
College of Medicine Research Institutes, Centers and FacilitiesEquipment/facility: Equipment