Institute for Personalized Medicine

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500 University Drive
17033 Hershey
United States

Organization profile

The mission of Penn State Institute for Personalized Medicine is to stimulate translational and clinical research into personalized health care at Penn State, facilitate the incorporation of this research into patient care and educate and advocate for the practice of personalized health care.

James Broach, PhD
- Department of Molecular and Precision Medicine - Distinguished Professor and Interim Chair
- Department of Otolaryngology - Head and Neck Surgery - Professor
- Institute for Personalized Medicine - Director
- Penn State Cancer Institute
- Cancer Institute, Next-Generation Therapies
Person: Academic
19752025
Dajiang Liu, PhD, MA
- Department of Public Health Sciences - Distinguished Professor and Vice Chair for Research
- Division of Biostatistics and Bioinformatics
- Department of Molecular and Precision Medicine - Distinguished Professor
- Institute for Personalized Medicine
- Penn State Cancer Institute
- One Health Microbiome Center
- Cancer Institute, Cancer Control
Person: Academic
20102025
Vonn Walter, PhD
Person: Academic
20112025

60203 Citations
108 h-index
460 Article
25 Review article
12 Comment/debate
10 Conference contribution
More

An atlas of single-cell eQTLs dissects autoimmune disease genes and identifies novel drug classes for treatment
Wang, L., Markus, H., Chen, D., Chen, S., Zhang, F., Gao, S., Khunsriraksakul, C., Chen, F., Olsen, N., Foulke, G., Jiang, B., Carrel, L. & Liu, D. J., Apr 9 2025, In: Cell Genomics. 5, 4, 100820.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Link opens in a new tab Scopus citations
A Systematic Review of Human Paenibacillus Infections and Comparison of Adult and Pediatric Cases
Smith, D., Bastug, K., Burgoine, K., Broach, J. R., Hammershaimb, E. A., Hehnly, C., Morton, S. U., Osman, M., Schiff, S. J. & Ericson, J. E., May 1 2025, In: Pediatric Infectious Disease Journal. 44, 5, p. 455-461 7 p.
Research output: Contribution to journal › Article › peer-review
4 Link opens in a new tab Scopus citations
Correction to: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (Nature Neuroscience, (2021), 24, 10, (1367-1376), 10.1038/s41593-021-00908-3)
COGA Collaborators, Jan 2025, In: Nature Neuroscience. 28, 1, p. 213 1 p.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
2 Link opens in a new tab Scopus citations
Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia
Ding, Y., He, B., Bogush, D., Schramm, J., Singh, C., Dovat, K., Randazzo, J., Tukaramrao, D., Hengst, J., Annageldiyev, C., Kudva, A., Desai, D., Sharma, A., Spiegelman, V. S., Huang, S., Viet, C. T., Dorsam, G., Saulnier Scholler, G., Broach, J. & Yue, F. & 1 others, Dovat, S., Aug 2025, In: Leukemia. 39, 8, p. 2010-2020 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Current challenges and potential opportunities for interception and prevention of head and neck cancer
El-Bayoumy, K., Christensen, N., Broach, J., Meyers, C., Stairs, D., Machtay, M., Hu, J., Bitzer, Z. T., Schell, T. D., Chen, K.-M., Sun, Y.-W., Desai, D., Walter, V. & Zhu, J., Feb 1 2025, In: Carcinogenesis. 46, 2, bgaf025.
Research output: Contribution to journal › Review article › peer-review

Open Access
1 Link opens in a new tab Scopus citations
Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate
Khan, Y., Schmidt, A. M., Oldro, K. J., Zhu, X., Kramer, A. R., Hamilton, S. R., Bleil, K. O., Krisko, R. M., Zitzow, J. D., Tian, Y., Chang, S. C., Walter, V., Cohen, S. M., Gonzalez, F. J., Patterson, A. D. & Peters, J. M., May 1 2025, In: Toxicological Sciences. 205, 1, p. 47-52 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Link opens in a new tab Scopus citations
Future directions in the evaluation and management of newly diagnosed metastatic cancer
Lehrer, E. J., Khunsriraksakul, C., Garrett, S., Trifiletti, D. M., Sheehan, J. P., Guckenberger, M., Louie, A. V., Siva, S., Ost, P., Goodman, K. A., Dawson, L. A., Tchelebi, L. T., Yang, J. T., Showalter, T. N., Park, H. S., Spratt, D. E., Kishan, A. U., Gupta, G. P., Shah, C. & Fanti, S. & 9 others, Calais, J., Wang, M., Schmitz, K., Liu, D., Abraham, J. A., Dess, R. T., Buvat, I., Solomon, B. & Zaorsky, N. G., Apr 2025, In: Critical Reviews in Oncology/Hematology. 208, 104631.
Research output: Contribution to journal › Review article › peer-review

Open Access
1 Link opens in a new tab Scopus citations
Genome Instability Precedes Viral Integration in Human Papillomavirus–Transformed Tonsillar Keratinocytes
Chan, K., Tseng, C., Milarachi, E., Goldrich, D., Schneper, L., Sheldon, K., Aliaga, C., Alam, S., Chatterjee, S., El-Bayoumy, K., Meyers, C., Goldenberg, D. & Broach, J. R., Feb 1 2025, In: Molecular Cancer Research. 23, 2, p. 119-127 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Link opens in a new tab Scopus citations
Integrating axis quantitative trait loci looks beyond cell types and offers insights into brain-related traits
Wang, L., Gao, S., Chen, S., Markus, H., Wang, G., Carrel, L., Zhan, X., Liu, D. J. & Jiang, B., Dec 2025, In: Nature communications. 16, 1, 10606.
Research output: Contribution to journal › Article › peer-review

Open Access
Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages
Wang, C., Markus, H., Diwadkar, A. R., Khunsriraksakul, C., Carrel, L., Li, B., Zhong, X., Wang, X., Zhan, X., Foulke, G. T., Olsen, N., Liu, D. & Jiang, B., Dec 2025, In: Nature communications. 16, 1, 180.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Link opens in a new tab Scopus citations

COM-IPM-Bullet Blender (high-throughput tissue homogenizer)
Institute for Personalized Medicine
Equipment/facility: Equipment
COM-IPM-Covaris Adaptive Focused Acoustics Ultrasonicator E-Series
Institute for Personalized Medicine
Equipment/facility: Equipment
COM-IPM-QIA Symphony DNA/RNA Extraction Robot
Institute for Personalized Medicine
Equipment/facility: Equipment

3 Active
16 Finished

Multi-omic Characterization of COPD in Females
Liu, D. (PI), Manichaikul, A. W. (CoPI) & Shim, Y. Y. M. (CoPI)
National Heart, Lung, and Blood Institute
8/1/24 → 7/31/26
Project: Research project
Methods and tools to integrate multi-omics datasets to understand preclinical autoimmune and immune-mediated diseases
Liu, D. (PI)
National Institute of Allergy and Infectious Diseases
7/5/24 → 5/31/26
Project: Research project
Integrative genomic and geospatial analysis of insurance claim, biobank and GWAS summary statistics for complex traits
Liu, D. (PI) & Jiang, B. B. (CoPI)
National Institute of Environmental Health Sciences
6/20/23 → 3/31/26
Project: Research project
Integrative genomic and geospatial analysis of insurance claim, biobank and GWAS summary statistics for complex traits
Liu, D. (PI)
National Human Genome Research Institute
9/21/22 → 8/31/23
Project: Research project
Integrative approaches to understand systemic lupus erythematosus etiology in trans-ancestry genetic studies
Liu, D. (PI) & Carrel, L. (CoPI)
National Institute of Allergy and Infectious Diseases
9/20/22 → 7/31/25
Project: Research project
Methods to unveil sex-specific genetic architecture in trans-ancestry meta-analysis
Liu, D. (PI) & Jiang, B. (CoPI)
National Human Genome Research Institute
8/10/22 → 5/31/24
Project: Research project
Methods to maximize the utility of common fund functional genomic data in multi-ethnic genetic studies
Liu, D. (PI)
NIH Office of the Director
9/22/21 → 9/21/22
Project: Research project
Methods to Identify, Validate & Interpret GWAS Loci in Multi-ethnic Meta-analysis
Liu, D. (PI)
National Human Genome Research Institute
1/1/21 → 12/31/21
Project: Research project
Tools for integrative genomics and disease association study for the X chromosome
Liu, D. (PI)
National Institute of General Medical Sciences
8/1/18 → 6/30/22
Project: Research project
Method to Enhance the Rare Variant Genetic Architecture Analysis in Meta-Analyses
Liu, D. (PI)
National Human Genome Research Institute
5/16/16 → 4/30/21
Project: Research project

Career Citation Milestone Award - M (1000) Club
Barnstable, C. (Recipient) & Broach, J. (Recipient), 2017
Prize

Institute for Personalized Medicine

Organization profile

Organization profile

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

James Broach, PhD

Dajiang Liu, PhD, MA

Vonn Walter, PhD

An atlas of single-cell eQTLs dissects autoimmune disease genes and identifies novel drug classes for treatment

A Systematic Review of Human Paenibacillus Infections and Comparison of Adult and Pediatric Cases

Correction to: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (Nature Neuroscience, (2021), 24, 10, (1367-1376), 10.1038/s41593-021-00908-3)

Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia

Current challenges and potential opportunities for interception and prevention of head and neck cancer

Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate

Future directions in the evaluation and management of newly diagnosed metastatic cancer

Genome Instability Precedes Viral Integration in Human Papillomavirus–Transformed Tonsillar Keratinocytes

Integrating axis quantitative trait loci looks beyond cell types and offers insights into brain-related traits

Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages

COM-IPM-Bullet Blender (high-throughput tissue homogenizer)

COM-IPM-Covaris Adaptive Focused Acoustics Ultrasonicator E-Series

COM-IPM-QIA Symphony DNA/RNA Extraction Robot

Multi-omic Characterization of COPD in Females

Methods and tools to integrate multi-omics datasets to understand preclinical autoimmune and immune-mediated diseases

Integrative genomic and geospatial analysis of insurance claim, biobank and GWAS summary statistics for complex traits

Integrative genomic and geospatial analysis of insurance claim, biobank and GWAS summary statistics for complex traits

Integrative approaches to understand systemic lupus erythematosus etiology in trans-ancestry genetic studies

Methods to unveil sex-specific genetic architecture in trans-ancestry meta-analysis

Methods to maximize the utility of common fund functional genomic data in multi-ethnic genetic studies

Methods to Identify, Validate & Interpret GWAS Loci in Multi-ethnic Meta-analysis

Tools for integrative genomics and disease association study for the X chromosome

Method to Enhance the Rare Variant Genetic Architecture Analysis in Meta-Analyses

Career Citation Milestone Award - M (1000) Club

Institute for Personalized Medicine

Organization profile

Organization profile

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Equipment

Projects

Prizes