Projects per year
Personal profile
Research interests
The lab of Drs. Amanda Nelson and Diane Thiboutot is focused on understanding the skin-specific and immune mechanisms underlying inflammatory skin diseases associated with sebaceous glands and hair follicles, such as acne vulgaris and hidradenitis suppurativa. The lab is also interested in the role of innate immunity, specifically TLR signaling pathways, in normal keratinocytes and in non-melanoma skin cancer. Another focus of the laboratory is understanding the relationship between the skin microbiome, host immune response and changes that occur with the development of skin diseases or the treatment of skin diseases. Translational studies use cell culture, mouse models and samples from patients. The group uses its varied expertise in cell and molecular biology approaches and human subjects research to investigate the pathogenesis of skin diseases.
Teaching and educational interests
Dr. Amanda Nelson is a faculty member in the Biomedical Sciences (BMS) Graduate Program and the MD/PhD Medical Scientist Training Program at Penn State College of Medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Postdoctoral Fellowship, Johns Hopkins University School of Medicine
2010 → 2013
Postdoctoral Fellowship, Penn State College of Medicine
2007 → 2010
PhD, Penn State College of Medicine
… → 2007
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Collaborations and top research areas from the last five years
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Projects
- 2 Finished
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Adherens Junction dysfunction in Hidradenitis Suppurativa
Nelson, A. (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/21/22 → 8/31/23
Project: Research project
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Defining the role of Toll-like receptor 3 in skin homeostasis, injury and neoplasia
Nelson, A. (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
4/1/16 → 3/31/21
Project: Research project
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Functional Dynamics of Dendritic Cells in Response to Cutibacterium acnes Strains Associated with Healthy and Acne-Prone Skin
Del Vecchio, G., Nguyen, N. P. N., Ouyang, K., Odhiambo, C. O., Nelson, A. M., Deng, M., Pellegrini, M. & Agak, G. W., 2025, (Accepted/In press) In: Journal of Investigative Dermatology.Research output: Contribution to journal › Article › peer-review
Open Access -
What's Old Is New: Apocrine Gland Destruction in Hidradenitis Suppurativa
Nelson, A. M., 2025, (Accepted/In press) In: Journal of Investigative Dermatology.Research output: Contribution to journal › Comment/debate › peer-review
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Acne Vulgaris
Zaenglein, A. L., Nelson, A. & Lalor, L. E. B., Jan 1 2024, Dermatology: Volume 1-2, Fifth Edition. Elsevier, Vol. 1. p. 592-609 18 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Laser-Capture Microdissection–Based RNA Sequencing for Profiling Mouse and Human Sebaceous Gland Transcriptomes
Harris, J. C., Prouty, S. M., Nelson, M. A., Sung, D. C., Nelson, A. M., Seykora, J. T., Kambayashi, T. & Grice, E. A., May 2024, In: Journal of Investigative Dermatology. 144, 5, p. 1161-1165.e8Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Setting the Stage for Standardized Reporting of Clinical and Demographic Information in Laboratory-Based Studies of Hidradenitis Suppurativa
Schell, S. L. & Nelson, A. M., Aug 2024, In: Journal of Investigative Dermatology. 144, 8, p. 1689-1695 7 p.Research output: Contribution to journal › Short survey › peer-review
Prizes
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Dean's Award for Excellence in Teaching
Aprile, B. (Recipient), Bezinover, D. (Recipient), Blackall, G. (Recipient), Booth, J. (Recipient), Buchkovich, N. (Recipient), Budde, A. (Recipient), Burns, A. (Recipient), Cartee, T. (Recipient), Chu, D. C. (Recipient), Cilley, R. (Recipient), Crook, T. (Recipient), Dalke, K. (Recipient), Dambro, A. (Recipient), De Jesus, S. (Recipient), Demetriou, T. (Recipient), DeWaters, A. (Recipient), Duca, N. (Recipient), Evey, L. (Recipient), Frauenhoffer, E. (Recipient), Garner, M. (Recipient), Glass, K. (Recipient), Goyal, N. (Recipient), Grine, K. (Recipient), Habib, S. (Recipient), Irby, R. (Recipient), Jones, E. (Recipient), June, R. (Recipient), Karamchandani, K. (Recipient), Karpa, K. (Recipient), Kasmire, K. (Recipient), Katzman, M. (Recipient), Kavanagh, R. (Recipient), Kees-Folts, D. (Recipient), Kesterson, J. (Recipient), Sciacca Kirby, J. (Recipient), Kresch, M. (Recipient), Lankford, E. (Recipient), McDonald, A. (Recipient), Miller, R. (Recipient), Moldovan, G.-L. (Recipient), Myler, C. (Recipient), Nelson, A. (Recipient), Neutze, J. (Recipient), Newell, J. (Recipient), Norbury, C. (Recipient), O'Hara, C. (Recipient), Palmer, T. (Recipient), Pantanelli, S. (Recipient), Pichardo-Lowden, A. (Recipient), Po, W. (Recipient), Radico, J. (Recipient), Radtka, J. (Recipient), Razeghi, S. (Recipient), Rodgers, R. (Recipient), Romanoski, N. (Recipient), Samson, T. (Recipient), Shantz, L. (Recipient), Smith, B. (Recipient), Stephens, M. (Recipient) & Wang, M. (Recipient), 2019
Prize