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Personal profile

Research interests

Dr. Catharine I. Paules joined the faculty of Penn State College of Medicine in July 2018. She is a clinician-investigator with a research focus on COVID-19, emerging respiratory viruses and infections in bone marrow transplant recipients.

Dr. Paules was the site principle investigator (PI) for the NIAID-sponsored Adaptive COVID-19 treatment trial and the NIH-sponsored ACTIV-5 / Big Effect Trial (BET-B) for the Treatment of COVID-19. She is now the site PI for the NIH sponsored STRIVE trial to study strategies and treatments for patients with COVID-19 and other respiratory viruses. She is also involved in the COVID-19 Project ECHO for Nursing Homes and the NIH Recover initiative for Long COVID.

Teaching and educational interests

Dr. Paules is committed to the mentorship and teaching of medical students, residents, fellows and other trainees. She has multiple publications involving trainees and in 2021 a resident she mentored received the resident research award. Dr. Paules is also actively engaged in community education with involvement in infectious diseases educational forums and media outreach.

Clinical interests

Dr. Paules developed an infectious diseases consult service at Penn State Health for patients who have received (or are planned to receive) a bone marrow transplant. This specialty service sees patients in both the inpatient and outpatient setting. Dr. Paules is also involved in Bio-preparedness and serves as a member of Penn State Health's Special Pathogens Team. She was integral in the institution's clinical, research, and logistical responses to the COVID-19 pandemic.

Professional information

Board-certified, Internal Medicine, American Board of Internal Medicine, 2015

Board-certified, Infectious Diseases, American Board of Internal Medicine, 2016

Alpha Omega Alpha (AOA) Honor Medical Society, University of Nebraska Medical Center, 2011

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Infectious Diseases, Fellowship, National Institutes of Health

… → 2016

Internal Medicine, Residency, University of Maryland Medical Center

… → 2014

MD, University of Nebraska

… → 2011

BS, College of William and Mary

… → 2007


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