Research output per year
Research output per year
Personal profile
Research interests
Dr. Chandrika Gowda is a board-certified hematologist/oncologist who has strong commitment to research in childhood cancer, including leukemia and neuroblastoma. Her major research project is to study Role of Ikaros tumor suppressor and pro-oncogenic casein Kinase II(CK2) in leukemogenesis and drug resistance. Dr.Gowda's current work is focused on targeting CK2 for treatment of hematological malignancies.
Her most notable work, published in Blood in 2015, established the novel approach of using specific CK2 inhibitors for treatment of high-risk B cell lineage leukemia using PDX models. She has presented her work at various national and international scientific forums and gained national recognition as an outstanding young investigator.
Dr. Gowda's research is currently supported by several extramural grants. She has also authored several chapters and review articles related to leukemia, CK2 and Ikaros. Her other projects are focused on designing novel therapeutic strategies for treatment of high risk neuroblastoma, which is the most common abdominal solid tumor in young children, with poor prognosis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Pediatric Hematology/Oncology, Clinical Fellowship, Pennsylvania State University
2010 → 2013
Pediatrics, Residency, Monmouth Medical Center
2007 → 2010
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Collaborations and top research areas from the last five years
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Signaling pathways and regulation of gene expression in hematopoietic cells
Bogush, D., Schramm, J., Ding, Y., He, B., Singh, C., Sharma, A., Tukaramrao, D. B., Iyer, S., Desai, D., Nalesnik, G., Hengst, J., Bhalodia, R., Gowda, C. & Dovat, S., May 2023, In: Advances in Biological Regulation. 88, 100942.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Chronic Generalized Lymphadenopathy in a Child—Progressive Transformation of Germinal Centers (PTGC)
Wills, C., Mercer, K., Malysz, J., Galvis, L. R. & Gowda, C., Feb 2022, In: Children. 9, 2, 214.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Clinician-Scientist Faculty Mentoring Program (FAME) – A New Inclusive Training Model at Penn State Increases Scholarly Productivity and Extramural Grant Funding
Dovat, S., Gowda, C., Mailman, R. B., Parent, L. J. & Huang, X., 2022, In: Advances in Medical Education and Practice. 13, p. 1039-1050 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Novel Casein Kinase II (CK2) inhibitor BMS-135 shows significant in vivo anti-leukemia effect
Gowda, C., Purandare, A., Mercer, K., Duke, K. & Dovat, S., Oct 2022, In: European Journal of Cancer. 174, p. S29Research output: Contribution to journal › Article › peer-review
Open Access -
Dual targeting of MTOR as a novel therapeutic approach for high-risk B-cell acute lymphoblastic leukemia
Ge, Z., Song, C., Ding, Y., Tan, B. H., Desai, D., Sharma, A., Gowda, R., Yue, F., Huang, S., Spiegelman, V., Payne, J. L., Reeves, M. E., Iyer, S., Dhanyamraju, P. K., Imamura, Y., Bogush, D., Bamme, Y., Yang, Y., Soliman, M. & Kane, S. & 8 others, , May 2021, In: Leukemia. 35, 5, p. 1267-1278 12 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations
Prizes
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Distinguished Educator Award
Behura, C. (Recipient), DeWaters, A. (Recipient), George, M. (Recipient) & Williams, E. (Recipient), 2024
Prize
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Scholarship in Education Award
Acharya, V. (Recipient), Foy, A. (Recipient), Vrana, K. (Recipient), Huang, X. (Recipient), Chetlen, A. (Recipient), Dovat, S. (Recipient), Gowda, C. (Recipient), Acharya, J. (Recipient) & Murray, M. (Recipient), 2022
Prize