Dr. Charles Dye's research interests primarily focus on interventional endoscopy and cancerous/pre-cancerous conditions in gastroenterology. His current research projects include EUS-guided ablation of premalignant pancreatic cysts as a co-investigator of the NIH funded CHARM II multi-center randomized clinical trial, Endoscopic Mucosal Resection (EMR), endoscopic cryotherapy, and innovative advanced endoscopy techniques. Dr Dye has also been involved in several intellectual property and endoscopic technology projects. These projects include the Chimera Project which is a joint project with Penn State University Bioengineering to develop an endoscopic ultrasound (EUS)-guided device which uses the twin modalities of radiofrequency ablation and targeted external beam radiation to treat solid abdominal mass lesions.