Projects per year
Personal profile
Research interests
Computational protein design; enzyme and antibody engineering; reconstruction, curation and analysis of metabolic networks; computational strain design and synthetic biology; metabolism of photosynthetic organisms; metabolism of obligatory anaerobes; modeling of microbial communities; optimization theory and algorithms.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Chemical Engineering, PhD, Global Optimization in Molecular Design, Princeton Univercity
Award Date: Oct 16 1995
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Collaborations and top research areas from the last five years
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Collaborative Research: EDGE FGT: Development of a Comprehensive Selection Library to Reconcile Core Metabolic Knowledge Gaps
Maranas, C. D. (PI)
8/15/23 → 7/31/26
Project: Research project
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Collaborative Research: Designing a Minimized Genome Cyanobacterial Chassis for Efficient Bioproduction
Maranas, C. D. (PI)
2/15/21 → 1/31/26
Project: Research project
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Collaborative Research: Systems analysis of the interplay between oxygenic photosynthesis and nitrogen fixation in a unicellular cyanobacterium
Maranas, C. D. (PI)
8/15/19 → 7/31/24
Project: Research project
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Collaborative Research: SusChEM: Unlocking the fundamental mechanisms that underlie selectivity in oleochemical producing enzymes
Maranas, C. D. (PI)
9/1/17 → 8/31/21
Project: Research project
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Collaborative Research: From genotype to fluxome to a comprehensive kinetic model of Escherichia coli
Maranas, C. D. (PI)
8/15/16 → 7/31/21
Project: Research project
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Reconstruction of a resource balance analysis model of Clostridium thermocellum examines the metabolic cost of glycolytic and cellulosome enzymes
Willis, T. C., Schroeder, W. L., Khana, D. B., Qian, X., Dahal, S., Amador-Noguez, D. & Maranas, C. D., Jan 2026, In: Metabolic engineering. 93, p. 14-23 10 p.Research output: Contribution to journal › Article › peer-review
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CatPred: a comprehensive framework for deep learning in vitro enzyme kinetic parameters
Boorla, V. S. & Maranas, C. D., Dec 2025, In: Nature communications. 16, 1, 2072.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid
Upadhyay, V., Li, H., He, J., Ocampo, B. E., Cook, S., Zhao, H. & Maranas, C. D., Apr 18 2025, In: ACS Synthetic Biology. 14, 4, p. 1112-1120 9 p.Research output: Contribution to journal › Article › peer-review
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minChemBio: Expanding Chemical Synthesis with Chemo-Enzymatic Pathways Using Minimal Transitions
Anand, M., Upadhyay, V. & Maranas, C. D., Mar 21 2025, In: ACS Synthetic Biology. 14, 3, p. 756-770 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection
Upadhyay, V., Anand, M. & Maranas, C. D., Aug 2025, In: PLoS computational biology. 21, 8 August, e1012516.Research output: Contribution to journal › Article › peer-review
Open Access