Dajiang Liu
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Dajiang Liu, PhD, MA

    Calculated based on number of publications stored in Pure and citations from Scopus
    20102023

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    • 2023

      Association of surfactant protein A2 with acute respiratory failure in children

      Emery, L., Kane, E., Anderson-Fears, K., Liu, D., Floros, J. & Gandhi, C. K., Jan 1 2023, In: Pediatrics International. 65, 1, e15672.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus

      Khunsriraksakul, C., Li, Q., Markus, H., Patrick, M. T., Sauteraud, R., McGuire, D., Wang, X., Wang, C., Wang, L., Chen, S., Shenoy, G., Li, B., Zhong, X., Olsen, N. J., Carrel, L., Tsoi, L. C., Jiang, B. & Liu, D. J., Dec 2023, In: Nature communications. 14, 1, 668.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing

      Chen, F., Wang, X., Jang, S. K., Quach, B. C., Weissenkampen, J. D., Khunsriraksakul, C., Yang, L., Sauteraud, R., Albert, C. M., Allred, N. D. D., Arnett, D. K., Ashley-Koch, A. E., Barnes, K. C., Barr, R. G., Becker, D. M., Bielak, L. F., Bis, J. C., Blangero, J., Boorgula, M. P., Chasman, D. I., & 70 othersChavan, S., Chen, Y. D. I., Chuang, L. M., Correa, A., Curran, J. E., David, S. P., Fuentes, L. D. L., Deka, R., Duggirala, R., Faul, J. D., Garrett, M. E., Gharib, S. A., Guo, X., Hall, M. E., Hawley, N. L., He, J., Hobbs, B. D., Hokanson, J. E., Hsiung, C. A., Hwang, S. J., Hyde, T. M., Irvin, M. R., Jaffe, A. E., Johnson, E. O., Kaplan, R., Kardia, S. L. R., Kaufman, J. D., Kelly, T. N., Kleinman, J. E., Kooperberg, C., Lee, I. T., Levy, D., Lutz, S. M., Manichaikul, A. W., Martin, L. W., Marx, O., McGarvey, S. T., Minster, R. L., Moll, M., Moussa, K. A., Naseri, T., North, K. E., Oelsner, E. C., Peralta, J. M., Peyser, P. A., Psaty, B. M., Rafaels, N., Raffield, L. M., Reupena, M. S., Rich, S. S., Rotter, J. I., Schwartz, D. A., Shadyab, A. H., Sheu, W. H. H., Sims, M., Smith, J. A., Sun, X., Taylor, K. D., Telen, M. J., Watson, H., Weeks, D. E., Weir, D. R., Yanek, L. R., Young, K. A., Young, K. L., Zhao, W., Hancock, D. B., Jiang, B., Vrieze, S. & Liu, D. J., Feb 2023, In: Nature Genetics. 55, 2, p. 291-300 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Native American genetic ancestry and pigmentation allele contributions to skin color in a caribbean population

      Ang, K. C., Canfield, V. A., Foster, T. C., Harbaugh, T. D., Early, K. A., Harter, R. L., Reid, K. P., Leong, S. L., Kawasawa, Y. I., Liu, D. J., Hawley, J. W. & Cheng, K. C., 2023, In: eLife. 12, e77514.

      Research output: Contribution to journal › Article › peer-review

      Open Access
    • 2022

      Analysis of KIR gene variants in The Cancer Genome Atlas and UK Biobank using KIRCLE

      Gao, G. F., Liu, D., Zhan, X. & Li, B., Dec 2022, In: BMC Biology. 20, 1, 191.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Association of Spinal Cord Stimulator Implantation with Persistent Opioid Use in Patients with Postlaminectomy Syndrome

      Vu, T. N., Khunsriraksakul, C., Vorobeychik, Y., Liu, A., Sauteraud, R., Shenoy, G., Liu, D. J. & Cohen, S. P., 2022, (Accepted/In press) In: JAMA network open. e2145876.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder

      Jang, S. K., Saunders, G., Liu, M. Z., Jiang, Y., Liu, D. J. & Vrieze, S., Apr 7 2022, In: Psychological medicine. 52, 5, p. 968-978 11 p.

      Research output: Contribution to journal › Article › peer-review

      35 Scopus citations

    • Genetic diversity fuels gene discovery for tobacco and alcohol use

      23andMe Research Team & The Biobank Japan Project, Dec 22 2022, In: Nature. 612, 7941, p. 720-724 5 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      34 Scopus citations

    • Heavy metals as risk factors for human diseases – a Bayesian network approach

      Perrelli, M., Wu, R., Liu, D. J., Lucchini, R. G., Del Bosque-Plata, L., Vergare, M. J., Akhter, M. P., Ott, J. & Gragnoli, C., 2022, In: European Review for Medical and Pharmacological Sciences. 26, 24, p. 9275-9310 36 p.

      Research output: Contribution to journal › Article › peer-review

      3 Scopus citations

    • Hydrophilic But Not Hydrophobic Surfactant Protein Genetic Variants Are Associated With Severe Acute Respiratory Syncytial Virus Infection in Children

      Depicolzuane, L. C., Roberts, C. M., Thomas, N. J., Anderson-Fears, K., Liu, D., Barbosa, J. P. P., Souza, F. R., Pimentel, A. S., Floros, J. & Gandhi, C. K., Jul 12 2022, In: Frontiers in immunology. 13, 922956.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Integrating 3D genomic and epigenomic data to enhance target gene discovery and drug repurposing in transcriptome-wide association studies

      Khunsriraksakul, C., McGuire, D., Sauteraud, R., Chen, F., Yang, L., Wang, L., Hughey, J., Eckert, S., Dylan Weissenkampen, J., Shenoy, G., Marx, O., Carrel, L., Jiang, B. & Liu, D. J., Dec 2022, In: Nature communications. 13, 1, 3258.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations

    • MB-SupCon: Microbiome-based Predictive Models via Supervised Contrastive Learning

      Yang, S., Wang, S., Wang, Y., Rong, R., Kim, J., Li, B., Koh, A. Y., Xiao, G., Li, Q., Liu, D. J. & Zhan, X., Aug 15 2022, In: Journal of Molecular Biology. 434, 15, 167693.

      Research output: Contribution to journal › Article › peer-review

      3 Scopus citations

    • Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes

      AMP-T2D-GENES, Myocardial Infarction Genetics Consortium, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium & NHLBI TOPMed Lipids Working Group, Jan 6 2022, In: American Journal of Human Genetics. 109, 1, p. 81-96 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      15 Scopus citations

    • Rare genetic variants explain missing heritability in smoking

      Jang, S. K., Evans, L., Fialkowski, A., Arnett, D. K., Ashley-Koch, A. E., Barnes, K. C., Becker, D. M., Bis, J. C., Blangero, J., Bleecker, E. R., Boorgula, M. P., Bowden, D. W., Brody, J. A., Cade, B. E., Jenkins, B. W. C., Carson, A. P., Chavan, S., Cupples, L. A., Custer, B., Damrauer, S. M., & 70 othersDavid, S. P., de Andrade, M., Dinardo, C. L., Fingerlin, T. E., Fornage, M., Freedman, B. I., Garrett, M. E., Gharib, S. A., Glahn, D. C., Haessler, J., Heckbert, S. R., Hokanson, J. E., Hou, L., Hwang, S. J., Hyman, M. C., Judy, R., Justice, A. E., Kaplan, R. C., Kardia, S. L. R., Kelly, S., Kim, W., Kooperberg, C., Levy, D., Lloyd-Jones, D. M., Loos, R. J. F., Manichaikul, A. W., Gladwin, M. T., Martin, L. W., Nouraie, M., Melander, O., Meyers, D. A., Montgomery, C. G., North, K. E., Oelsner, E. C., Palmer, N. D., Payton, M., Peljto, A. L., Peyser, P. A., Preuss, M., Psaty, B. M., Qiao, D., Rader, D. J., Rafaels, N., Redline, S., Reed, R. M., Reiner, A. P., Rich, S. S., Rotter, J. I., Schwartz, D. A., Shadyab, A. H., Silverman, E. K., Smith, N. L., Smith, J. G., Smith, A. V., Smith, J. A., Tang, W., Taylor, K. D., Telen, M. J., Vasan, R. S., Gordeuk, V. R., Wang, Z., Wiggins, K. L., Yanek, L. R., Yang, I. V., Young, K. A., Young, K. L., Zhang, Y., Liu, D. J., Keller, M. C. & Vrieze, S., Nov 2022, In: Nature Human Behaviour. 6, 11, p. 1577-1586 10 p.

      Research output: Contribution to journal › Article › peer-review

      7 Scopus citations

    • RNAseq reveals extensive metabolic disruptions in the sensitive SF-295 cell line treated with schweinfurthins

      Weissenrieder, J. S., Weissenkampen, J. D., Reed, J. L., Green, M. V., Zheng, C., Neighbors, J. D., Liu, D. J. & Hohl, R. J., Dec 2022, In: Scientific reports. 12, 1, 359.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Type 1 Diabetes in Acute Pancreatitis Consortium: From Concept to Reality

      Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), Jul 1 2022, In: Pancreas. 51, 6, p. 563-567 5 p.

      Research output: Contribution to journal › Article › peer-review

      5 Scopus citations
    • 2021

      Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis

      Patrick, M. T., Stuart, P. E., Zhang, H., Zhao, Q., Yin, X., He, K., Zhou, X. J., Mehta, N. N., Voorhees, J. J., Boehnke, M., Gudjonsson, J. E., Nair, R. P., Handelman, S. K., Elder, J. T., Liu, D. J. & Tsoi, L. C., Jun 2021, In: Journal of Investigative Dermatology. 141, 6, p. 1493-1502 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      21 Scopus citations

    • Inferring genes that escape X-Chromosome inactivation reveals important contribution of variable escape genes to sex-biased diseases

      Sauteraud, R., Stahl, J. M., James, J., Englebright, M., Chen, F., Zhan, X., Carrel, L. & Liu, D. J., Sep 2021, In: Genome research. 31, 9, p. 1629-1637 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • MB-GAN: Microbiome Simulation via Generative Adversarial Network

      Rong, R., Jiang, S., Xu, L., Xiao, G., Xie, Y., Liu, D. J., Li, Q. & Zhan, X., Feb 1 2021, In: GigaScience. 10, 2, giab005.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Medical Service Use and Charges for Cancer Care in 2018 for Privately Insured Patients Younger Than 65 Years in the US

      Zaorsky, N. G., Khunsriraksakul, C., Acri, S. L., Liu, D. J., Ba, D. M., Lin, J. L., Liu, G., Segel, J. E., Drabick, J. J., Mackley, H. B. & Leslie, D. L., Oct 6 2021, In: JAMA network open. 4, 10, 27784.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • MetaPrism: A versatile toolkit for joint taxa/gene analysis of metagenomic sequencing data

      Kim, J., Jiang, S., Yiqing, W., Xiao, G., Xie, Y., Liu, D. J., Li, Q., Koh, A. & Zhan, X., Apr 2021, In: G3: Genes, Genomes, Genetics. 11, 4, jkab046.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Model-based assessment of replicability for genome-wide association meta-analysis

      GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN), Dec 1 2021, In: Nature communications. 12, 1, 1964.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      15 Scopus citations

    • Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

      COGA Collaborators, Oct 2021, In: Nature Neuroscience. 24, 10, p. 1367-1376 10 p.

      Research output: Contribution to journal › Article › peer-review

      81 Scopus citations
    • 2020

      Association analysis and meta-analysis of multiallelic variants for large-scale sequence data

      Jiang, Y., Chen, S., Wang, X., Liu, M., Iacono, W. G., Hewitt, J. K., Hokanson, J. E., Krauter, K., Laakso, M., Li, K. W., Lutz, S. M., McGue, M., Pandit, A., Zajac, G. J. M., Boehnke, M., Abecasis, G. R., Vrieze, S. I., Jiang, B., Zhan, X. & Liu, D. J., May 2020, In: Genes. 11, 5, 585.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

      LifeLines Cohort Study, EPIC-CVD, EPIC-InterAct, Understanding Society Scientific Group & Million Veteran Program, Dec 1 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.

      Research output: Contribution to journal › Article › peer-review

      63 Scopus citations

    • Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

      Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, Erzurumluoglu, A. M., Liu, M., Jackson, V. E., Barnes, D. R., Datta, G., Melbourne, C. A., Young, R., Batini, C., Surendran, P., Jiang, T., Adnan, S. D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A. C., Asselbergs, F. W., Baumbach, C., Bierut, L., Bertelsen, S., & 31 othersBoehnke, M., Bots, M. L., Brazel, D. M., Chambers, J. C., Chang-Claude, J., Chen, C., Corley, J., Chou, Y. L., David, S. P., de Boer, R. A., de Leeuw, C. A., Dennis, J. G., Dominiczak, A. F., Dunning, A. M., Easton, D. F., Eaton, C., Elliott, P., Evangelou, E., Faul, J. D., Foroud, T., Goate, A., Gong, J., Grabe, H. J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A. R., Harris, S. E., Hattersley, A., Heath, A. & Liu, D., Oct 1 2020, In: Molecular Psychiatry. 25, 10, p. 2392-2409 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      65 Scopus citations

    • Prioritizing genetic variants in GWAS with lasso using permutation-assisted tuning

      Yang, S., Wen, J., Eckert, S. T., Wang, Y., Liu, D. J., Wu, R., Li, R. & Zhan, X., Mar 31 2020, In: Bioinformatics. 36, 12, p. 3811-3817 7 p.

      Research output: Contribution to journal › Article › peer-review

      12 Scopus citations

    • Seqminer2: An efficient tool to query and retrieve genotypes for statistical genetics analyses from biobank scale sequence dataset

      Yang, L., Jiang, S., Jiang, B., Liu, D. J. & Zhan, X., Oct 1 2020, In: Bioinformatics. 36, 19, p. 4951-4954 4 p.

      Research output: Contribution to journal › Article › peer-review

    • 2019

      Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

      CHD Exome+ Consortium, Consortium for Genetics of Smoking Behaviour, Brazel, D. M., Jiang, Y., Hughey, J. M., Turcot, V., Zhan, X., Gong, J., Batini, C., Weissenkampen, J. D., Liu, M. Z., Surendran, P., Young, R., Barnes, D. R., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Kontto, J., Perola, M., & 32 othersCaslake, M., de Craen, A. J. M., Trompet, S., Uria-Nickelsen, M., Malarstig, A., Reily, D. F., Hoek, M., Vogt, T., Jukema, J. W., Sattar, N., Ford, I., Packard, C. J., Alam, D. S., Majumder, A. A. S., Di Angelantonio, E., Chowdhury, R., Amouyel, P., Arveiler, D., Blankenberg, S., Ferrières, J., Kee, F., Kuulasmaa, K., Müller-Nurasyid, M., Veronesi, G., Virtamo, J., EPIC-CVD Consortium, C., Frossard, P., Nordestgaard, B. G., Saleheen, D., Danesh, J., Butterworth, A. S. & Liu, D., Jun 1 2019, In: Biological Psychiatry. 85, 11, p. 946-955 10 p.

      Research output: Contribution to journal › Article › peer-review

      46 Scopus citations

    • Methods for the Analysis and Interpretation for Rare Variants Associated with Complex Traits

      Weissenkampen, J. D., Jiang, Y., Eckert, S., Jiang, B., Li, B. & Liu, D. J., Apr 2019, In: Current protocols in human genetics. 101, 1, e83.

      Research output: Contribution to journal › Article › peer-review

      10 Scopus citations

    • Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

      T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium, Mar 1 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

      Research output: Contribution to journal › Article › peer-review

      61 Scopus citations
    • 2018

      Adaptive-weight burden test for associations between quantitative traits and genotype data with complex correlations

      Wu, X., Guan, T., Liu, D. J., Novelo, L. G. L. & Bandyopadhyay, D., Sep 2018, In: Annals of Applied Statistics. 12, 3, p. 1558-1582 25 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

      The Geisinger-Regeneron DiscovEHR Collaboration, The VA Million Veteran Program, Global Lipids Genetics Consortium & Myocardial Infarction Genetics (MIGen) Consortium, Nov 1 2018, In: Nature Genetics. 50, 11, p. 1514-1523 10 p.

      Research output: Contribution to journal › Article › peer-review

      345 Scopus citations

    • Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes

      Jiang, Y., Chen, S., McGuire, D., Chen, F., Liu, M., Iacono, W. G., Hewitt, J. K., Hokanson, J. E., Krauter, K., Laakso, M., Li, K. W., Lutz, S. M., McGue, M., Pandit, A., Zajac, G. J. M., Boehnke, M., Abecasis, G. R., Vrieze, S. I., Zhan, X., Jiang, B., & 1 othersLiu, D. J., Jul 2018, In: PLoS genetics. 14, 7, e1007452.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

      Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T., & 379 othersFeitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Allison, M., Amouyel, P., Asselbergs, F. W., Auer, P. L., Balkau, B., Bang, L. E., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Bots, M. L., Bottinger, E. P., Bowden, D. W., Brandslund, I., Breen, G., Brilliant, M. H., Broer, L., Brumat, M., Burt, A. A., Butterworth, A. S., Campbell, P. T., Cappellani, S., Carey, D. J., Catamo, E., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Cocca, M., Cook, J. P., Corley, J., Corominas Galbany, J., Cox, A. J., Crosslin, D. S., Cuellar-Partida, G., D'Eustacchio, A., Danesh, J., Davies, G., Bakker, P. I. W., Groot, M. C. H., Mutsert, R., Deary, I. J., Dedoussis, G., Demerath, E. W., Heijer, M., Hollander, A. I., Ruijter, H. M., Dennis, J. G., Denny, J. C., Angelantonio, E., Drenos, F., Du, M., Dubé, M. P., Dunning, A. M., Easton, D. F., Edwards, T. L., Ellinghaus, D., Ellinor, P. T., Elliott, P., Evangelou, E., Farmaki, A. E., Farooqi, I. S., Faul, J. D., Fauser, S., Feng, S., Ferrannini, E., Ferrieres, J., Florez, J. C., Ford, I., Fornage, M., Franco, O. H., Franke, A., Franks, P. W., Friedrich, N., Frikke-Schmidt, R., Galesloot, T. E., Gan, W., Gandin, I., Gasparini, P., Gibson, J., Giedraitis, V., Gjesing, A. P., Gordon-Larsen, P., Gorski, M., Grabe, H. J., Grant, S. F. A., Grarup, N., Griffiths, H. L., Grove, M. L., Gudnason, V., Gustafsson, S., Haessler, J., Hakonarson, H., Hammerschlag, A. R., Hansen, T., Harris, K. M., Harris, T. B., Hattersley, A. T., Have, C. T., Hayward, C., He, L., Heard-Costa, N. L., Heath, A. C., Heid, I. M., Helgeland, Ø., Hernesniemi, J., Hewitt, A. W., Holmen, O. L., Hovingh, G. K., Howson, J. M. M., Hu, Y., Huang, P. L., Huffman, J. E., Ikram, M. A., Ingelsson, E., Jackson, A. U., Jansson, J. H., Jarvik, G. P., Jensen, G. B., Jia, Y., Johansson, S., Jørgensen, M. E., Jørgensen, T., Jukema, J. W., Kahali, B., Kahn, R. S., Kähönen, M., Kamstrup, P. R., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, S. L. R., Karpe, F., Kathiresan, S., Kee, F., Kiemeney, L. A., Kim, E., Kitajima, H., Komulainen, P., Kooner, J. S., Kooperberg, C., Korhonen, T., Kovacs, P., Kuivaniemi, H., Kutalik, Z., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, T. A., Lamparter, D., Lange, E. M., Lange, L. A., Langenberg, C., Larson, E. B., Lee, N. R., Lehtimäki, T., Lewis, C. E., Li, H., Li, J., Li-Gao, R., Lin, H., Lin, K. H., Lin, L. A., Lin, X., Lind, L., Lindström, J., Linneberg, A., Liu, C. T., Liu, D. J., Liu, Y., Lo, K. S., Lophatananon, A., Lotery, A. J., Loukola, A., Luan, JA., Lubitz, S. A., Lyytikäinen, L. P., Männistö, S., Marenne, G., Mazul, A. L., McCarthy, M. I., McKean-Cowdin, R., Medland, S. E., Meidtner, K., Milani, L., Mistry, V., Mitchell, P., Mohlke, K. L., Moilanen, L., Moitry, M., Montgomery, G. W., Mook-Kanamori, D. O., Moore, C., Mori, T. A., Morris, A. D., Morris, A. P., Müller-Nurasyid, M., Munroe, P. B., Nalls, M. A., Narisu, N., Nelson, C. P., Neville, M., Nielsen, S. F., Nikus, K., Njølstad, P. R., Nordestgaard, B. G., Nyholt, D. R., O'Connel, J. R., O'Donoghue, M. L., Olde Loohuis, L. M., Ophoff, R. A., Owen, K. R., Packard, C. J., Padmanabhan, S., Palmer, C. N. A., Palmer, N. D., Pasterkamp, G., Patel, A. P., Pattie, A., Pedersen, O., Peissig, P. L., Peloso, G. M., Pennell, C. E., Perola, M., Perry, J. A., Perry, J. R. B., Pers, T. H., Person, T. N., Peters, A., Petersen, E. R. B., Peyser, P. A., Pirie, A., Polasek, O., Polderman, T. J., Puolijoki, H., Raitakari, O. T., Rasheed, A., Rauramaa, R., Reilly, D. F., Renström, F., Rheinberger, M., Ridker, P. M., Rioux, J. D., Rivas, M. A., Roberts, D. J., Robertson, N. R., Robino, A., Rolandsson, O., Rudan, I., Ruth, K. S., Saleheen, D., Salomaa, V., Samani, N. J., Sapkota, Y., Sattar, N., Schoen, R. E., Schreiner, P. J., Schulze, M. B., Scott, R. A., Segura-Lepe, M. P., Shah, S. H., Sheu, W. H. H., Sim, X., Slater, A. J., Small, K. S., Smith, A. V., Southam, L., Spector, T. D., Speliotes, E. K., Starr, J. M., Stefansson, K., Steinthorsdottir, V., Stirrups, K. E., Strauch, K., Stringham, H. M., Stumvoll, M., Sun, L., Surendran, P., Swift, A. J., Tada, H., Tansey, K. E., Tardif, J. C., Taylor, K. D., Teumer, A., Thompson, D. J., Thorleifsson, G., Thorsteinsdottir, U., Thuesen, B. H., Tönjes, A., Tromp, G., Trompet, S., Tsafantakis, E., Tuomilehto, J., Tybjaerg-Hansen, A., Tyrer, J. P., Uher, R., Uitterlinden, A. G., Uusitupa, M., Laan, S. W., Duijn, C. M., Leeuwen, N., Van Setten, J., Vanhala, M., Varbo, A., Varga, T. V., Varma, R., Velez Edwards, D. R., Vermeulen, S. H., Veronesi, G., Vestergaard, H., Vitart, V., Vogt, T. F., Völker, U., Vuckovic, D., Wagenknecht, L. E., Walker, M., Wallentin, L., Wang, F., Wang, C. A., Wang, S., Wang, Y., Ware, E. B., Wareham, N. J., Warren, H. R., Waterworth, D. M., Wessel, J., White, H. D., Willer, C. J., Wilson, J. G., Witte, D. R., Wood, A. R., Wu, Y., Yaghootkar, H., Yao, J., Yao, P., Yerges-Armstrong, L. M., Young, R., Zeggini, E., Zhan, X., Zhang, W., Zhao, J. H., Zhao, W., Zhou, W., Zondervan, K. T., Rotter, J. I., Pospisilik, J. A., Rivadeneira, F., Borecki, I. B., Deloukas, P., Frayling, T. M., Lettre, G., North, K. E., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., Jan 1 2018, In: Nature Genetics. 50, 1, p. 26-35 10 p.

      Research output: Contribution to journal › Article › peer-review

      218 Scopus citations

    • Rare loss of function variants in candidate genes and risk of colorectal cancer

      NHLBI GO Exome Sequencing Project, Pulmonary Arterial Hypertension (PAH), Severe Asthma Research Program (SARP), Women’s Health Initiative (WHI), Anthropometry Project Team, Blood Count/Hematology Project Team, Blood Pressure Project Team, Data Flow Working Group, Early MI Project Team, ELSI Working Group, Executive Committee, Family Study Project Team, Lipids Project Team, Lung Project Team, Personal Genomics Project Team, Phenotype and Harmonization Working Group, Population Genetics and Statistical Analysis Working Group, Publications and Presentations Working Group, Quantitative Analysis Ad Hoc Task Group, Sequencing and Genotyping Working Group, & 15 othersSteering Committee, Stroke Project Team, Structural Variation Working Group, Subclinical/Quantitative Project Team, Acute Lung Injury (ALI), Atherosclerosis Risk in Communities (ARIC), Cardiovascular Health Study (CHS), Chronic Obstructive Pulmonary Disease (COPDGene), Coronary Artery Risk Development in Young Adults (CARDIA), Cystic Fibrosis (CF), Early Pseudomonas Infection Control (EPIC), Framingham Heart Study (FHS), Jackson Heart Study (JHS), Lung Health Study (LHS) & Multi-Ethnic Study of Atherosclerosis (MESA), Oct 1 2018, In: Human genetics. 137, 10, p. 795-806 12 p.

      Research output: Contribution to journal › Article › peer-review

      7 Scopus citations

    • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article

      ExomeBP Consortium, MAGIC Consortium & GIANT Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

      Research output: Contribution to journal › Article › peer-review

      261 Scopus citations
    • 2017

      Analysis of single nucleotide variants of HFE gene and association to survival in the Cancer Genome Atlas GBM data

      Lee, S. Y., Zhu, J., Salzberg, A. C., Zhang, B., Liu, D. J., Muscat, J. E., Langan, S. T. & Connor, J. R., Mar 2017, In: PloS one. 12, 3, e0174778.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      4 Scopus citations

    • Association of rare and common variation in the lipoprotein lipase gene with coronary artery disease

      Khera, A. V., Won, H. H., Peloso, G. M., O'Dushlaine, C., Liu, D., Stitziel, N. O., Natarajan, P., Nomura, A., Emdin, C. A., Gupta, N., Borecki, I. B., Asselta, R., Duga, S., Merlini, P. A., Correa, A., Kessler, T., Wilson, J. G., Bown, M. J., Hall, A. S., Braund, P. S., & 24 othersCarey, D. J., Murray, M. F., Kirchner, H. L., Leader, J. B., Lavage, D. R., Manus, J. N., Hartzel, D. N., Samani, N. J., Schunkert, H., Marrugat, J., Elosua, R., McPherson, R., Farrall, M., Watkin, H., Lander, E. S., Rader, D. J., Danesh, J., Ardissino, D., Gabriel, S., Willer, C., Abecasis, G. R., Saleheen, D., Dewey, F. E. & Kathiresan, S., Mar 7 2017, In: JAMA - Journal of the American Medical Association. 317, 9, p. 937-946 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      124 Scopus citations

    • Clonal evolution in paired endometrial intraepithelial neoplasia/atypical hyperplasia and endometrioid adenocarcinoma

      Russo, M., Broach, J., Sheldon, K., Houser, K. R., Liu, D. J., Kesterson, J., Phaeton, R., Hossler, C., Hempel, N., Baker, M., Newell, J. M., Zaino, R. & Warrick, J. I., Sep 2017, In: Human Pathology. 67, p. 69-77 9 p.

      Research output: Contribution to journal › Article › peer-review

      26 Scopus citations

    • Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease

      Lu, X., Peloso, G. M., Liu, D. J., Wu, Y., Zhang, H., Zhou, W., Li, J., Tang, C. S. M., Dorajoo, R., Li, H., Long, J., Guo, X., Xu, M., Spracklen, C. N., Chen, Y., Liu, X., Zhang, Y., Khor, C. C., Liu, J., Sun, L., & 47 othersWang, L., Gao, Y. T., Hu, Y., Yu, K., Wang, Y., Cheung, C. Y. Y., Wang, F., Huang, J., Fan, Q., Cai, Q., Chen, S., Shi, J., Yang, X., Zhao, W., Sheu, W. H. H., Cherny, S. S., He, M., Feranil, A. B., Adair, L. S., Gordon-Larsen, P., Du, S., Varma, R., Chen, Y. D. I., Shu, X. O., Lam, K. S. L., Wong, T. Y., Ganesh, S. K., Mo, Z., Hveem, K., Fritsche, L. G., Nielsen, J. B., Tse, H. F., Huo, Y., Cheng, C. Y., Chen, Y. E., Zheng, W., Tai, E. S., Gao, W., Lin, X., Huang, W., Abecasis, G., Kathiresan, S., Mohlke, K. L., Wu, T., Sham, P. C., Gu, D. & Willer, C. J., Dec 1 2017, In: Nature Genetics. 49, 12, p. 1722-1730 9 p.

      Research output: Contribution to journal › Article › peer-review

      98 Scopus citations

    • Exome-wide association study of plasma lipids in >300,000 individuals

      Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C., & 207 othersBoehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y. D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A., Dubé, M. P., Ebeling, T., Eiriksdottir, G., Esko, T., Farmaki, A. E., Feitosa, M. F., Ferrario, M., Ferrieres, J., Ford, I., Fornage, M., Franks, P. W., Frayling, T. M., Frikke-Schmidt, R., Fritsche, L. G., Frossard, P., Fuster, V., Ganesh, S. K., Gao, W., Garcia, M. E., Gieger, C., Giulianini, F., Goodarzi, M. O., Grallert, H., Grarup, N., Groop, L., Grove, M. L., Gudnason, V., Hansen, T., Harris, T. B., Hayward, C., Hirschhorn, J. N., Holmen, O. L., Huffman, J., Huo, Y., Hveem, K., Jabeen, S., Jackson, A. U., Jakobsdottir, J., Jarvelin, M. R., Jensen, G. B., Jørgensen, M. E., Jukema, J. W., Justesen, J. M., Kamstrup, P. R., Kanoni, S., Karpe, F., Kee, F., Khera, A. V., Klarin, D., Koistinen, H. A., Kooner, J. S., Kooperberg, C., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, T., Langenberg, C., Langsted, A., Launer, L. J., Lauritzen, T., MLiewald, D. C., Lin, L. A., Linneberg, A., Loos, R. J. F., Lu, Y., Lu, X., Mägi, R., Malarstig, A., Manichaikul, A., Manning, A. K., Mäntyselkä, P., Marouli, E., Masca, N. G. D., Maschio, A., Meigs, J. B., Melander, O., Metspalu, A., Morris, A. P., Morrison, A. C., Mulas, A., Müller-Nurasyid, M., Munroe, P. B., Neville, M. J., Nielsen, S. F., Nielsen, J. B., Nordestgaard, B. G., Ordovas, J. M., Mehran, R., O'Donnell, C. J., Orho-Melander, M., Molony, C. M., Muntendam, P., Padmanabhan, S., Palmer, C. N. A., Pasko, D., Patel, A. P., Pedersen, O., Perola, M., Peters, A., Pisinger, C., Pistis, G., Polasek, O., Poulter, N., Psaty, B. M., Rader, D. J., Rasheed, A., Rauramaa, R., Reilly, D. F., Reiner, A. P., Renström, F., Rich, S. S., Ridker, P. M., Rioux, J. D., Robertson, N. R., Roden, D. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sanna, S., Sattar, N., Schmidt, E. M., Scott, R. A., Sever, P., Sevilla, R. S., Shaffer, C. M., Sim, X., Sivapalaratnam, S., Small, K. S., Smith, A. V., Smith, B. H., Somayajula, S., Southam, L., Spector, T. D., Speliotes, E. K., Starr, J. M., Stirrups, K. E., Stitziel, N., Strauch, K., Stringham, H. M., Surendran, P., Tada, H., Tall, A. R., Tang, H., Tardif, J. C., Taylor, K. D., Trompet, S., Tsao, P. S., Tuomilehto, J., Tybjaerg-Hansen, A., Zuydam, N. R. V., Varbo, A., Varga, T. V., Virtamo, J., Waldenberger, M., Wang, N., Wareham, N. J., Warren, H. R., Weeke, P. E., Weinstock, J., Wessel, J., Wilson, J. G., Wilson, P. W. F., Xu, M., Yaghootkar, H., Young, R., Zeggini, E., Zhang, H., Zheng, N. S., Zhang, W., Zhang, Y., Zhou, W., Zhou, Y., Zoledziewska, M., Howson, J. M. M., Danesh, J., McCarthy, M. I., Cowan, C. A., Abecasis, G., Deloukas, P., Musunuru, K., Willer, C. J. & Kathiresan, S., Dec 1 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.

      Research output: Contribution to journal › Article › peer-review

      377 Scopus citations

    • Rare and low-frequency coding variants alter human adult height

      MAGIC Investigators, The EPIC-InterAct Consortium, EPIC-CVD Consortium, CHD Exome+ Consortium, ExomeBP Consortium, T2D-Genes Consortium, GoT2D Genes Consortium, Global Lipids Genetics Consortium & ReproGen Consortium, Feb 9 2017, In: Nature. 542, 7640, p. 186-190 5 p.

      Research output: Contribution to journal › Article › peer-review

      394 Scopus citations

    • Robust and rapid algorithms facilitate large-scale whole genome sequencing downstream analysis in an integrative framework

      Li, M., Li, J., Li, M. J., Pan, Z., Hsu, J. S., Liu, D. J., Zhan, X., Junwen, W., Youqiang, S. & Sham, P. C., May 19 2017, In: Nucleic acids research. 45, 9, e75.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      34 Scopus citations

    • SEQSpark: A Complete Analysis Tool for Large-Scale Rare Variant Association Studies Using Whole-Genome and Exome Sequence Data

      Zhang, D., Zhao, L., Li, B., He, Z., Wang, G. T., Liu, D. J. & Leal, S. M., Jul 6 2017, In: American Journal of Human Genetics. 101, 1, p. 115-122 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations
    • 2016

      Genetic variants in CETP increase risk of intracerebral hemorrhage

      on behalf of the Global Lipids Genetics Consortium and International Stroke Genetics Consortium, Nov 1 2016, In: Annals of Neurology. 80, 5, p. 730-740 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      29 Scopus citations

    • Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

      Eicher, J. D., Chami, N., Kacprowski, T., Nomura, A., Chen, M. H., Yanek, L. R., Tajuddin, S. M., Schick, U. M., Slater, A. J., Pankratz, N., Polfus, L., Schurmann, C., Giri, A., Brody, J. A., Lange, L. A., Manichaikul, A., Hill, W. D., Pazoki, R., Elliot, P., Evangelou, E., & 93 othersTzoulaki, I., Gao, H., Vergnaud, A. C., Mathias, R. A., Becker, D. M., Becker, L. C., Burt, A., Crosslin, D. R., Lyytikäinen, L. P., Nikus, K., Hernesniemi, J., Kähönen, M., Raitoharju, E., Mononen, N., Raitakari, O. T., Lehtimäki, T., Cushman, M., Zakai, N. A., Nickerson, D. A., Raffield, L. M., Quarells, R., Willer, C. J., Peloso, G. M., Abecasis, G. R., Liu, D. J., Deloukas, P., Samani, N. J., Schunkert, H., Erdmann, J., Fornage, M., Richard, M., Tardif, J. C., Rioux, J. D., Dube, M. P., de Denus, S., Lu, Y., Bottinger, E. P., Loos, R. J. F., Smith, A. V., Harris, T. B., Launer, L. J., Gudnason, V., Velez Edwards, D. R., Torstenson, E. S., Liu, Y., Tracy, R. P., Rotter, J. I., Rich, S. S., Highland, H. M., Boerwinkle, E., Li, J., Lange, E., Wilson, J. G., Mihailov, E., Mägi, R., Hirschhorn, J., Metspalu, A., Esko, T., Vacchi-Suzzi, C., Nalls, M. A., Zonderman, A. B., Evans, M. K., Engström, G., Orho-Melander, M., Melander, O., O'Donoghue, M. L., Waterworth, D. M., Wallentin, L., White, H. D., Floyd, J. S., Bartz, T. M., Rice, K. M., Psaty, B. M., Starr, J. M., Liewald, D. C. M., Hayward, C., Deary, I. J., Greinacher, A., Völker, U., Thiele, T., Völzke, H., van Rooij, F. J. A., Uitterlinden, A. G., Franco, O. H., Dehghan, A., Edwards, T. L., Ganesh, S. K., Kathiresan, S., Faraday, N., Auer, P. L., Reiner, A. P., Lettre, G. & Johnson, A. D., Jul 7 2016, In: American Journal of Human Genetics. 99, 1, p. 40-55 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      68 Scopus citations

    • Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

      Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., Trompet, S., Wouter Jukema, J., De Craen, A., Deloukas, P., Sattar, N., Ford, I., Packard, C., Majumder, A. A. S., Alam, D. S., Di Angelantonio, E., & 29 othersAbecasis, G., Chowdhury, R., Erdmann, J., Nordestgaard, B. G., Nielsen, S. F., Tybjærg-Hansen, A., Ruth Frikke Schmidt, F. S., Kuulasmaa, K., Liu, D. J., Perola, M., Blankenberg, S., Salomaa, V., Männistö, S., Amouyel, P., Arveiler, D., Ferrieres, J., Möller-Nurasyid, M., Ferrario, M., Kee, F., Willer, C. J., Samani, N., Schunkert, H., Butterworth, A. S., Howson, J. M. M., Peloso, G. M., Stitziel, N. O., Danesh, J., Kathiresan, S. & Rader, D. J., Mar 11 2016, In: Science. 351, 6278, p. 1166-1171 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      403 Scopus citations

    • RVTESTS: An efficient and comprehensive tool for rare variant association analysis using sequence data

      Zhan, X., Hu, Y., Li, B., Abecasis, G. R. & Liu, D. J., May 1 2016, In: Bioinformatics. 32, 9, p. 1423-1426 4 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      230 Scopus citations
    • 2015

      Methods for association analysis and meta-analysis of rare variants in families

      Feng, S., Pistis, G., Zhang, H., Zawistowski, M., Mulas, A., Zoledziewska, M., Holmen, O. L., Busonero, F., Sanna, S., Hveem, K., Willer, C., Cucca, F., Liu, D. J. & Abecasis, G. R., May 1 2015, In: Genetic Epidemiology. 39, 4, p. 227-238 12 p.

      Research output: Contribution to journal › Article › peer-review

      12 Scopus citations