Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Daniela Zarnescu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach
Zarnescu, D. (PI)
5/1/22 → …
Project: Research project
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Translation dysregulation in neurodegeneration
Zarnescu, D. (PI) & Zarnescu, D. D. C. (CoPI)
National Institute of Neurological Disorders and Stroke
2/15/22 → 1/31/25
Project: Research project
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Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach
Zarnescu, D. (PI)
Congressionally Directed Medical Research Programs
1/1/21 → …
Project: Research project
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Small Molecules Targeting TDP-43-RNA Interactions in ALS
Zarnescu, D. (PI)
7/1/18 → …
Project: Research project
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Mechanisms underlying the protective role of glycolysis in ALS
Zarnescu, D. (PI)
National Institute of Neurological Disorders and Stroke
9/30/20 → 5/31/22
Project: Research project
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Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits
Godfrey, R. K., Alsop, E., Bjork, R. T., Chauhan, B. S., Ruvalcaba, H. C., Antone, J., Gittings, L. M., Michael, A. F., Williams, C., Hala’ufia, G., Blythe, A. D., Hall, M., Sattler, R., Van Keuren-Jensen, K. & Zarnescu, D. C., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 168.Research output: Contribution to journal › Article › peer-review
Open Access -
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
Hung, S. T., Linares, G. R., Chang, W. H., Eoh, Y., Krishnan, G., Mendonca, S., Hong, S., Shi, Y., Santana, M., Kueth, C., Macklin-Isquierdo, S., Perry, S., Duhaime, S., Maios, C., Chang, J., Perez, J., Couto, A., Lai, J., Li, Y. & Alworth, S. V. & 8 others, , Feb 16 2023, In: Cell. 186, 4, p. 786-802.e28Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Dysregulation of Translation in TDP-43 Proteinopathies: Deficits in the RNA Supply Chain and Local Protein Production
Bjork, R. T., Mortimore, N. P., Loganathan, S. & Zarnescu, D. C., Mar 7 2022, In: Frontiers in Neuroscience. 16, 840357.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
TDP-43 Proteinopathy Causes Broad Metabolic Alterations including TCA Cycle Intermediates and Dopamine Levels in Drosophila Models of ALS
Loganathan, S., Wilson, B. A., Carey, S. B., Manzo, E., Joardar, A., Ugur, B. & Zarnescu, D. C., Feb 2022, In: Metabolites. 12, 2, 101.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Author Correction: Mutations disrupting neuritogenesis genes confer risk for cerebral palsy (Nature Genetics, (2020), 52, 10, (1046-1056), 10.1038/s41588-020-0695-1)
Jin, S. C., Lewis, S. A., Bakhtiari, S., Zeng, X., Sierant, M. C., Shetty, S., Nordlie, S. M., Elie, A., Corbett, M. A., Norton, B. Y., van Eyk, C. L., Haider, S., Guida, B. S., Magee, H., Liu, J., Pastore, S., Vincent, J. B., Brunstrom-Hernandez, J., Papavasileiou, A. & Fahey, M. C. & 57 others, , Mar 2021, In: Nature Genetics. 53, 3, p. 412 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations
Prizes
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Dean's Award for Excellence in Teaching
Hussein, R. (Recipient), Stredny, E. (Recipient), Whitley, M. (Recipient), Mnatsakanyan, N. (Recipient), Raimundo, N. (Recipient), Zarnescu, D. (Recipient), Adams, N. (Recipient), Lanza, M. (Recipient), Kowalczyk, A. (Recipient), Travelute, C. (Recipient), Marco, C. (Recipient), Tondt, J. (Recipient), Anderson, A. (Recipient), Heron, C. (Recipient), Newman, R. (Recipient), Richard, D. (Recipient), Scartozzi, C. (Recipient), Dellasega, C. (Recipient), Akhtar, N. (Recipient), Albano-Aluquin, S. (Recipient), Chisty, A. (Recipient), Crook, T. (Recipient), Federici, E. H. (Recipient), Ingram, D. (Recipient), Lakshmanan, P. (Recipient), Mathew, A. (Recipient), Narayana, S. (Recipient), Prokop, A. (Recipient), Razjouyan, H. (Recipient), Tariq, A. (Recipient), Thompson, B. (Recipient), Thompson, E. (Recipient), Trivedi, N. (Recipient), Van Scoy, L. (Recipient), Wong, J. (Recipient), Allie, S. R. (Recipient), Browning, K. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Mamarabadi, M. (Recipient), Shankar, L. (Recipient), Bowie, E. (Recipient), Petfield, J. (Recipient), Whitaker, M. (Recipient), Aynardi, J. (Recipient), Allen, N. (Recipient), Cunningham, B. (Recipient), Gandhi, C. (Recipient), Jairath, B. (Recipient), Lutzkanin, K. M. (Recipient), Kerris, E. (Recipient), Nelson, A. (Recipient), Shook, J. (Recipient), Proctor, E. A. (Recipient), Raup-Konsavage, W. (Recipient), Romanoski, N. (Recipient), Graziane, J. (Recipient), Llorente, A. (Recipient), Nutting, S. (Recipient), Pinto, C. (Recipient), Yingst, J. (Recipient), Zhou, S. (Recipient), Mahase, S. (Recipient), Brian, P. (Recipient), Goldman, E. (Recipient), Maffie, J. (Recipient), Brahmbhatt, R. (Recipient), Fahy, A. (Recipient), Gish, J. (Recipient), Reed, M. F. (Recipient) & Tomasko, J. (Recipient), 2024
Prize