Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Edward P. O'Brien, Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Center: National Synthesis Center for Emergence in the Molecular and Cellular Sciences
Honavar, V. G. (CoPI) & O'Brien, Jr., E. P. (PI)
5/1/24 → 4/30/29
Project: Research project
-
MoCeIS-DCL: Planning Workshops for Synthesis of Massively Parallel Assays and Molecular Physiology
O'Brien, Jr., E. P. (PI), Lareau, L. L. (CoPI), Marqusee, S. S. (CoPI), Shah, P. P. (CoPI) & Thirumalai, D. (CoPI)
9/1/21 → 8/31/22
Project: Research project
-
Machine Learning Guided Biophysical Model Development of Amino Acid and tRNA Effects on Translation-Elongation Speed
O'Brien, Jr., E. P. (PI)
1/1/21 → 12/31/23
Project: Research project
-
Conference: Protein Folding on the Ribosome
O'Brien, Jr., E. P. (PI) & Kaiser, C. C. (CoPI)
8/1/20 → 7/31/22
Project: Research project
-
CC* Team: Research Innovation with Scientists and Engineers (RISE)
Hanna, C. R. (PI), O'Brien, Jr., E. P. (CoPI) & Evans, J. (CoPI)
7/1/20 → 6/30/23
Project: Research project
-
Deciphering the free energy landscapes of SARS-CoV-2 wild type and Omicron variant interacting with human ACE2
Lan, P. D., Nissley, D. A., O’Brien, E. P., Nguyen, T. T. & Li, M. S., Feb 7 2024, In: Journal of Chemical Physics. 160, 5, 055101.Research output: Contribution to journal › Article › peer-review
-
It is theoretically possible to avoid misfolding into non-covalent lasso entanglements using small molecule drugs
Jiang, Y., Deane, C. M., Morris, G. M. & O’Brien, E. P., Mar 2024, In: PLoS computational biology. 20, 3 March, e1011901.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Non-covalent Lasso Entanglements in Folded Proteins: Prevalence, Functional Implications, and Evolutionary Significance
Rana, V., Sitarik, I., Petucci, J., Jiang, Y., Song, H. & O'Brien, E. P., Mar 15 2024, In: Journal of Molecular Biology. 436, 6, 168459.Research output: Contribution to journal › Article › peer-review
Open Access -
Synonymous Mutations Can Alter Protein Dimerization Through Localized Interface Misfolding Involving Self-entanglements
Lan, P. D., Nissley, D. A., Sitarik, I., Vu, Q. V., Jiang, Y., To, P., Xia, Y., Fried, S. D., Li, M. S. & O'Brien, E. P., Mar 15 2024, In: Journal of Molecular Biology. 436, 6, 168487.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
How soluble misfolded proteins bypass chaperones at the molecular level
Halder, R., Nissley, D. A., Sitarik, I., Jiang, Y., Rao, Y., Vu, Q. V., Li, M. S., Pritchard, J. & O’Brien, E. P., Dec 2023, In: Nature communications. 14, 1, 3689.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations