Projects per year
Personal profile
Research interests
Dr. Elizabeth Proctor’s laboratory aims to characterize the systems biology of complex diseases at multiple scales (molecular, cellular, tissue and physiological) with the ultimate goal of providing tools for early diagnosis and identifying novel preventative and therapeutic strategies.
Her laboratory combines multiplexing experiments with computational modeling and machine learning to identify patterns associated with disease pathology, then manipulates the identified variables in cell culture and/or in animal models to test their ability to alter and control disease state.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Postdoctoral Fellowship, Massachusetts Institute of Technology
… → 2018
PhD, University of North Carolina at Chapel Hill
… → 2013
BS, BA, Purdue University
… → 2008
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Collaborations and top research areas from the last five years
Projects
- 3 Finished
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Impaired Vasoreactivity, Sleep Degradation, and Impaired Clearance in the APOE4 Brain
Proctor, E. A., Gluckman, B. & Drew, P. J.
7/15/22 → 3/31/23
Project: Research project
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Coupling and spread of molecular and functional pathology of Alzheimer's disease
5/1/21 → 4/30/23
Project: Research project
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Identification of drug leads targeting SOD1 dissociation for the treatment of ALS
12/1/10 → 11/30/13
Project: Research project
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Apolipoprotein E ε4 modulates astrocyte neuronal support functions in the presence of amyloid-β
Fleeman, R. M., Kuhn, M. K., Chan, D. C. & Proctor, E. A., May 2023, In: Journal of neurochemistry. 165, 4, p. 536-549 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Predictive link between systemic metabolism and cytokine signatures in the brain of apolipoprotein E ε4 mice
Fleeman, R. M., Snyder, A., Kuhn, M. K., Chan, D. C., Smith, G. C., Crowley, N. A., Arnold, A. C. & Proctor, E. A., Mar 2023, In: Neurobiology of Aging. 123, p. 154-169 16 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
Zukowski, E., Sannella, M., Rockhold, J. D., Kalantar, G. H., Yu, J., SantaCruz-Calvo, S., Kuhn, M. K., Hah, N., Ouyang, L., Wang, T. W., Murphy, L., Marszalkowski, H., Gibney, K., Drummond, M. J., Proctor, E. A., Hasturk, H., Nikolajczyk, B. S. & Bharath, L. P., Nov 2023, In: Aging cell. 22, 11, e13996.Research output: Contribution to journal › Article › peer-review
Open Access -
Monosialotetrahexosylganglioside Promotes Early Aβ42 Oligomer Formation and Maintenance
Zhang, D. Y., Wang, J., Fleeman, R. M., Kuhn, M. K., Swulius, M. T., Proctor, E. A. & Dokholyan, N. V., Jul 6 2022, In: ACS Chemical Neuroscience. 13, 13, p. 1979-1991 13 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Astrocytic Propagation of Tau in the Context of Alzheimer's Disease
Fleeman, R. M. & Proctor, E. A., Mar 17 2021, In: Frontiers in Cellular Neuroscience. 15, 645233.Research output: Contribution to journal › Review article › peer-review
Open Access24 Scopus citations