Projects per year
Personal profile
Research interests
Dr. Elizabeth Proctor’s laboratory aims to characterize the systems biology of complex diseases at multiple scales (molecular, cellular, tissue and physiological) with the ultimate goal of providing tools for early diagnosis and identifying novel preventative and therapeutic strategies.
Her laboratory combines multiplexing experiments with computational modeling and machine learning to identify patterns associated with disease pathology, then manipulates the identified variables in cell culture and/or in animal models to test their ability to alter and control disease state.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Postdoctoral Fellowship, Massachusetts Institute of Technology
… → 2018
PhD, University of North Carolina at Chapel Hill
… → 2013
BS, BA, Purdue University
… → 2008
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Collaborations and top research areas from the last five years
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Impaired Vasoreactivity, Sleep Degradation, and Impaired Clearance in the APOE4 Brain
Proctor, E. A. (PI), Gluckman, B. (CoPI) & Drew, P. J. (CoPI)
7/15/22 → 3/31/27
Project: Research project
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Coupling and spread of molecular and functional pathology of Alzheimer's disease
Proctor, E. A. (PI) & Zhang, N. (CoPI)
5/1/21 → 4/30/24
Project: Research project
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Identification of drug leads targeting SOD1 dissociation for the treatment of ALS
Proctor, E. A. (PI)
12/1/10 → 11/30/13
Project: Research project
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Differential responses of primary neuron-secreted MCP-1 and IL-9 to type 2 diabetes and Alzheimer’s disease-associated metabolites
Ball, B. K., Kuhn, M. K., Fleeman Bechtel, R. M., Proctor, E. A. & Brubaker, D. K., Dec 2024, In: Scientific reports. 14, 1, 12743.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Everolimus alleviates CD4+ T cell inflammation by regulating autophagy and cellular redox homeostasis
Rockhold, J. D., Marszalkowski, H., Sannella, M., Gibney, K., Murphy, L., Zukowski, E., Kalantar, G. H., SantaCruz-Calvo, S., Hart, S. N., Kuhn, M. K., Yu, J., Stefanik, O., Chase, G., Proctor, E. A., Hasturk, H., Nikolajczyk, B. S. & Bharath, L. P., Dec 2024, In: GeroScience. 46, 6, p. 5681-5699 19 p.Research output: Contribution to journal › Article › peer-review
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Amyloid-β Pathology-Specific Cytokine Secretion Suppresses Neuronal Mitochondrial Metabolism
Kuhn, M. K., Fleeman, R. M., Beidler, L. M., Snyder, A. M., Chan, D. C. & Proctor, E. A., Aug 2023, In: Cellular and Molecular Bioengineering. 16, 4, p. 405-421 17 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Apolipoprotein E ε4 modulates astrocyte neuronal support functions in the presence of amyloid-β
Fleeman, R. M., Kuhn, M. K., Chan, D. C. & Proctor, E. A., May 2023, In: Journal of neurochemistry. 165, 4, p. 536-549 14 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Predictive link between systemic metabolism and cytokine signatures in the brain of apolipoprotein E ε4 mice
Fleeman, R. M., Snyder, A., Kuhn, M. K., Chan, D. C., Smith, G. C., Crowley, N. A., Arnold, A. C. & Proctor, E. A., Mar 2023, In: Neurobiology of Aging. 123, p. 154-169 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations
Prizes
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Dean's Award for Excellence in Teaching
Hussein, R. (Recipient), Stredny, E. (Recipient), Whitley, M. (Recipient), Mnatsakanyan, N. (Recipient), Raimundo, N. (Recipient), Zarnescu, D. (Recipient), Adams, N. (Recipient), Lanza, M. (Recipient), Kowalczyk, A. (Recipient), Travelute, C. (Recipient), Marco, C. (Recipient), Tondt, J. (Recipient), Anderson, A. (Recipient), Heron, C. (Recipient), Newman, R. (Recipient), Richard, D. (Recipient), Scartozzi, C. (Recipient), Dellasega, C. (Recipient), Akhtar, N. (Recipient), Albano-Aluquin, S. (Recipient), Chisty, A. (Recipient), Crook, T. (Recipient), Federici, E. H. (Recipient), Ingram, D. (Recipient), Lakshmanan, P. (Recipient), Mathew, A. (Recipient), Narayana, S. (Recipient), Prokop, A. (Recipient), Razjouyan, H. (Recipient), Tariq, A. (Recipient), Thompson, B. (Recipient), Thompson, E. (Recipient), Trivedi, N. (Recipient), Van Scoy, L. (Recipient), Wong, J. (Recipient), Allie, S. R. (Recipient), Browning, K. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Mamarabadi, M. (Recipient), Shankar, L. (Recipient), Bowie, E. (Recipient), Petfield, J. (Recipient), Whitaker, M. (Recipient), Aynardi, J. (Recipient), Allen, N. (Recipient), Cunningham, B. (Recipient), Gandhi, C. (Recipient), Jairath, B. (Recipient), Lutzkanin, K. M. (Recipient), Kerris, E. (Recipient), Nelson, A. (Recipient), Shook, J. (Recipient), Proctor, E. A. (Recipient), Raup-Konsavage, W. (Recipient), Romanoski, N. (Recipient), Graziane, J. (Recipient), Llorente, A. (Recipient), Nutting, S. (Recipient), Pinto, C. (Recipient), Yingst, J. (Recipient), Zhou, S. (Recipient), Mahase, S. (Recipient), Brian, P. (Recipient), Goldman, E. (Recipient), Maffie, J. (Recipient), Brahmbhatt, R. (Recipient), Fahy, A. (Recipient), Gish, J. (Recipient), Reed, M. F. (Recipient) & Tomasko, J. (Recipient), 2024
Prize
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