Calculated based on number of publications stored in Pure and citations from Scopus
20042023

Research activity per year

Personal profile

Research interests

The laboratory of Dr. Fadia Kamal studies cellular pathways that control chondrocyte homeostasis in healthy tissue and the key processes that transform them to pathological cells, which leads to cartilage damage and loss in osteoarthritis.

Osteoarthritis is a debilitating disease with no disease-modifying treatment available. Osteoarthritis is characterized by continuous and progressive cartilage loss leading to joint dysfunction. Chondrocyte, the functional cell of cartilage controls cartilage homeostasis by secreting cartilage matrix components and matrix degrading enzymes. In osteoarthritis, the chondrocyte acquires an aberrant phenotype, it differentiates to become hypertrophic and secretes higher levels of matrix degrading enzymes, ultimately leading to cartilage matrix degradation and cartilage loss.

The Kamal lab’s research focuses on discovering new pathways and drugs that target these disease pathways, and control chondrocyte behavior to delay or even reverse osteoarthritis disease process.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Fingerprint

Dive into the research topics where Fadia Kamal is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or