Projects per year
Personal profile
Research interests
Dr. Jeffrey Peters’ laboratory studies the role of the peroxisome proliferator-activated receptors (PPARs). PPARs modulate gene expression through direct and indirect mechanisms. His laboratory group uses genetically modified mouse and human models, high affinity agonists, antagonists and selective, repressive ligands to delineate the roles of PPARs, with a particular interest in cancers. Through their studies, they are elucidating the molecular mechanisms by which exogenous (dietary) and endogenous (metabolic sources) lipids specifically modulate human health. They are particularly interested in delineating how natural compounds can modulate PPARs with the goal of identifying new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Post-doctoral training, Laboratory of Molecular Carcinogenesis and Laboratory of Metabolism, National Cancer Institute
1995 → 1999
Post-doctoral training, University of California at Davis
1992 → 1995
External positions
Fellow, Academy of Toxicological Sciences
Jan 1 2012 → …
Fellow, Academy of Toxicological Sciences
2012 → …
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Unique targeting of PPARβ/δ regulation for cancer prevention and therapy
Peters, J. J. M., Patterson, A. D. & Peters, J. M.
12/6/19 → 11/30/23
Project: Research project
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Transcriptional regulation of polycyclic aromatic hydrocarbon metabolism
1/1/10 → 11/30/14
Project: Research project
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2021-2022 Toxicological Sciences paper of the year
Guo, L. & Peters, J. M., Mar 1 2023, In: Toxicological Sciences. 192, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice
Zhu, X., Liu, Q., Patterson, A. D., Sharma, A. K., Amin, S. G., Cohen, S. M., Gonzalez, F. J. & Peters, J. M., Aug 2023, In: Metabolites. 13, 8, 936.Research output: Contribution to journal › Article › peer-review
Open Access -
2020-2021 Toxicological Sciences Paper of the Year
States, J. C. & Peters, J. M., Mar 28 2022, In: Toxicological sciences : an official journal of the Society of Toxicology. 186, 2, p. 177-178 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells
Hirao-Suzuki, M., Takayuki, K., Takiguchi, M., Peters, J. M. & Takeda, S., Nov 30 2022, In: Archives of Biochemistry and Biophysics. 731, 109428.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice
Su, S., Billy, L. J., Chang, S., Gonzalez, F. J., Patterson, A. D. & Peters, J. M., Jan 15 2022, In: Toxicology. 465, 153056.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations
Activities
- 3 Oral presentation
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Unraveling the controversial role of peroxisome proliferator-activated receptor-β/δ in cancer
Jeffrey Maurice Peters (Keynote speaker)
2016 → …Activity: Talk types › Oral presentation
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Peroxisome proliferator-activated receptors as molecular targets for the treatment and prevention of diseases
Jeffrey Maurice Peters (Invited speaker)
2009 → …Activity: Talk types › Oral presentation
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PPARβ(δ)-dependent regulation of cell proliferation, differentiation and carcinogenesis: Studies from null mouse models
Jeffrey Maurice Peters (Invited speaker)
2005 → …Activity: Talk types › Oral presentation