Projects per year
Personal profile
Research interests
Dr. Jonathan Stine is an Associate Professor of Medicine and Public Health Sciences at Penn State where he serves as the Fatty Liver Program Director and Liver Center Research Director.
As an internationally recognized liver expert with a research and clinical focus on metabolic dysfunction-associated steatotic liver disease (MASLD), he has authored more than 115 peer-reviewed papers, including multinational consensus guidelines for the American College of Sports Medicine and Exercise and Sports Science Australia, and has lectured across the United States and Europe.
Dr. Stine has been the recipient of multiple research grants and awards from the American Association for the Study of Liver Diseases, American Cancer Society and National Institutes of Health.
His research has been featured by various media outlets including ABC, the Associated Press, Yahoo and STAT News. Since 2023, he has been recognized by Stanford University as being among the World’s Top 2% Scientists.
Clinical interests
Dr. Jonathan G. Stine is a transplant hepatologist and internationally recognized expert in liver disease with a primary clinical focus on metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH).
As Program Director of the Penn State Health Fatty Liver Program and Research Director for the Penn State Health Liver Center, his clinical practice integrates advanced diagnostics, multidisciplinary treatment, and evidence-based care to improve outcomes for patients with MASLD, MASH, and liver transplantation needs.
Dr. Stine is passionate about leveraging exercise and lifestyle interventions as foundational therapies for patients with metabolic liver disease, helping bridge the gap between emerging research and clinical application.
With decades of experience as a thought leader in hepatology, Dr. Stine’s work is informed by participation in over 30 MASLD/MASH clinical trials and development of multinational consensus guidelines. His approach to care is both compassionate and innovative, focusing on empowering patients through personalized treatment strategies that target the root causes of liver disease. By combining his clinical expertise with a commitment to improving patient quality of life, Dr. Stine continues to set new standards for managing metabolic liver disorders.
Professional information
Fellow of the American College of Physicians (FACP), 2016
Member, American Association for the Study of Liver Diseases
Member, American College of Gastroenterology
Member, American College of Sports Medicine
Member, European Association for the Study of the Liver
Member, International Liver Transplantation Society
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Transplant Hepatology Fellowship, NIH/NIDDK T32 training grant, University of Virginia
… → 2017
Gastroenterology and Hepatology Fellowship, NIH/NIDDK T32 training grant, University of Virginia
… → 2016
Clinical Research, MS, University of Virginia
… → 2015
Internal Medicine (Chief Resident, 2012-2013), Residency, Georgetown University Hospital
… → 2013
MD, Georgetown University
… → 2009
Nutritional Sciences, BS, The Pennsylvania State University
… → 2005
External positions
Nonalcoholic Fatty Liver Disease Consultant, Exercise is Medicine Initiative, American College of Sports Medicine
Member, NASH and Lifestyle Councils, Global Liver Institute
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Collaborations and top research areas from the last five years
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National Institutes of Health (NIH) Loan Repayment from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Stine, J. (PI)
7/1/18 → 6/30/20
Project: Research project
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Challenges in Promoting Physical Activity for Managing MASLD in Canadian Children: Insights and Barriers
Kehar, M., Huerta-Saenz, L., Strain, J., Kawesa, S., Yaraskavitch, J., Stine, J. & Longmuir, P. E., 2025, (Accepted/In press) In: Digestive Diseases and Sciences. 100182.Research output: Contribution to journal › Article › peer-review
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Multidisciplinary clinic model enhances liver and metabolic health outcomes in adults with MASH
Stine, J. G., Bradley, D., McCall-Hosenfeld, J., Motz-Patel, V., Tondt, J., Batra, S., Fitzgerald, B., Garcia, S., Hummer, B., Kindrew, C., Koppenhaver, A., Mohr, H., Smith, N., Tressler, H., Vankirk, K., Krok, K., Schreibman, I., Stonesifer, E. & Clarke, K., Feb 3 2025, In: Hepatology Communications. 9, 2, e0649.Research output: Contribution to journal › Article › peer-review
Open Access -
The Role of Exercise in Steatotic Liver Diseases: An Updated Perspective
Alabdul Razzak, I., Fares, A., Stine, J. G. & Trivedi, H. D., Jan 2025, In: Liver International. 45, 1, e16220.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Update on Newly Federal Drug Administration-Approved Drug, Resmetirom: A Practical Perspective
Barritt, A. S. & Stine, J. G., Feb 1 2025, In: American Journal of Gastroenterology. 120, 2, p. 272-276 5 p.Research output: Contribution to journal › Article › peer-review
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(P)rehabilitation in advanced chronic liver disease (advCLD): From basic exercise concepts to implementation challenges
Kassa, A. P. & Stine, J. G., Jun 2024, In: Clinical Liver Disease. 23, 1, e0184.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations
Prizes
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Junior Faculty Research Scholar Award
Hobbs, R. (Recipient), Graziane, N. (Recipient), Kwun, H. J. (Recipient) & Stine, J. (Recipient), 2018
Prize
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Activities
- 3 Invited talk
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Nonalcoholic fatty liver disease and Exercise is Medicine
Stine, J. (Speaker)
2020 → …Activity: Talk types › Invited talk
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Frailty in ICU- implications for transplant candidacy
Stine, J. (Speaker)
May 2019 → …Activity: Talk types › Invited talk
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Metabolic Syndrome After Transplantation
Stine, J. (Speaker)
2018 → …Activity: Talk types › Invited talk