Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Collaborative Research: MODULUS: Copy Number Alterations and Xenobiotic adaptation
Pritchard, J. (PI)
5/1/22 → 4/30/25
Project: Research project
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Extracellular Vesicle-Based Noninvasive Detection of PIK3CA Compound Mutation for Breast Cancer
Pritchard, J. (PI)
3/1/22 → …
Project: Research project
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Extracellular Vesicle-Based Noninvasive Detection of PIK3CA Compound Mutation for Breast Cancer
Pritchard, J. (PI)
Congressionally Directed Medical Research Programs
1/1/21 → …
Project: Research project
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RECODE: Real-time Monitoring, Modeling and Manipulation of Progenitor Co-differentiation in Heterotypic Cell Systems
Hayes, D. J. (CoPI), Hayes, D. J. (PI) & Pritchard, J. (CoPI)
1/1/21 → 12/31/25
Project: Research project
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Model Driven Construction of Dual-switch Selection Gene Drives to Combat Drug Resistance
Pritchard, J. (PI)
National Institute of Biomedical Imaging and Bioengineering
8/1/19 → 4/30/22
Project: Research project
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Programming tumor evolution with selection gene drives to proactively combat drug resistance
Leighow, S. M., Reynolds, J. A., Sokirniy, I., Yao, S., Yang, Z., Inam, H., Wodarz, D., Archetti, M. & Pritchard, J., 2024, (Accepted/In press) In: Nature Biotechnology.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
An engineered N-acyltransferase-LOV2 domain fusion protein enables light-inducible allosteric control of enzymatic activity
Reynolds, J. A., Vishweshwaraiah, Y. L., Chirasani, V. R., Pritchard, J. R. & Dokholyan, N. V., Apr 2023, In: Journal of Biological Chemistry. 299, 4, 103069.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions
Lawanprasert, A., Sloand, J. N., González Vargas, M., Singh, H., Eldor, T., Miller, M. A., Pimcharoen, S., Wang, J., Leighow, S. M., Pritchard, J. R., Dokholyan, N. V. & Medina, S. H., Jul 3 2023, In: ChemBioChem. 24, 13, e202300159.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing
Liu, C., Leighow, S. M., McIlroy, K., Lu, M., Dennis, K. A., Abello, K., Brown, D. J., Moore, C. J., Shah, A., Inam, H., Rivera, V. M. & Pritchard, J. R., Oct 17 2023, In: Cell Reports Medicine. 4, 10, 101227.Research output: Contribution to journal › Article › peer-review
Open Access -
How soluble misfolded proteins bypass chaperones at the molecular level
Halder, R., Nissley, D. A., Sitarik, I., Jiang, Y., Rao, Y., Vu, Q. V., Li, M. S., Pritchard, J. & O’Brien, E. P., Dec 2023, In: Nature communications. 14, 1, 3689.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations