Dr. Lin is interested in the pathogenesis and therapeutics of tissue fibrosis and inflammation. She has defined several molecular mechanisms of tPA and LRP-1 signaling in regulating fibroblast activation and survival during renal fibrogenesis. Her work has also uncovered a novel regulatory mechanism of NF-κB activation involving annexin A2-mediated CD11b integrin signal pathway, as well as the previously unrecognized role of NF-κB in macrophage migration and polarity shift from M2 to M1 during renal inflammation.

Currently, Dr. Lin is utilizing innovative approaches to investigate the role and signaling mechanism of cell-cell communication, as well as oxidative stress, in the pathogenesis of tissue fibrosis and inflammation, and to develop specific treatment targeting fibrosis and inflammation.

Dr. Lin is involved in the research advising and mentoring of graduate students, postdocs and visiting scholars.