Projects per year
Personal profile
Research interests
Dr. Matthew Coates is a physician-scientist with long-standing research interest relating to the interplay between inflammatory bowel disease (IBD) and neuroendocrine signaling systems. To this end, he has focused much of his effort evaluating intestinal serotonin, neurotrophic and other signaling systems in the context of IBD and other inflammatory disorders of the gut. He is also very interested in how these factors impact visceral sensation and other key functions of the gastrointestinal tract.
His laboratory utilizes a variety of innovative molecular (e.g., next-generation genomics, immunohistochemistry, immunoassays) and functional (e.g., quantitative sensory and visceromotor testing) techniques to investigate these issues.
Dr. Coates is also overseeing the development of a gastroenterology-based intestinal disease data registry and biorepository. As part of this effort, critical data and tissue samples (including endoscopically derived intestinal biopsies and blood) are collected in order to facilitate multi-modal, prospective studies related to the research interests described above as well as related topics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Gastroenterology, Hepatology and Nutrition, Fellowship, University of Pittsburgh School of Medicine
… → Aug 2013
Internal Medicine, Residency, University of Vermont College of Medicine
… → Jun 2010
MD, University of Vermont College of Medicine
… → May 2007
PhD, University of Vermont College of Medicine
… → May 2005
AB, Princeton University
… → Jun 1996
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease
Coates, M. (PI)
National Institute of Diabetes and Digestive and Kidney Diseases
4/10/20 → 1/31/24
Project: Research project
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The Role of Intestinal Mucosal Serotonin Uptake in IBS
Coates, M. (PI)
National Institute of Neurological Disorders and Stroke
6/29/05 → 6/28/06
Project: Research project
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Asymptomatic Erosive Esophagitis
Du, Y., Spencer, A., Roy, P., Abdulhamid, A., Dalessio, S., Levenick, J., Maranki, J., Razjouyan, H. & Coates, M., Feb 2025, In: Digestive Diseases and Sciences. 70, 2, p. 462-468 7 p., e0192739.Research output: Contribution to journal › Review article › peer-review
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Clinical characterization of the silent chronic pancreatitis patient: a single-center retrospective cohort study
Amakye, D., Bundschuh, M., Walter, V., Headlee, B., Razjouyan, H. & Coates, M., Sep 13 2024, In: Annals of Gastroenterology. 37, 5, p. 618-622 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinical outcomes associated with antidepressant use in inflammatory bowel disease patients and a matched control cohort
Ba, D. M., Yadav, S., Liu, G., Leslie, D. L., Vrana, K. E. & Coates, M. D., Dec 2024, In: Scientific reports. 14, 1, 1060.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Economics of Emergency Department Visits by Patients With Inflammatory Bowel Disease: A Real-World Analysis
Clarke, K., Momin, A., Rosario, M., Stuart, A., Dalessio, S., Tinsley, A., Williams, E. & Coates, M., Apr 1 2024, In: Crohn's and Colitis 360. 6, 2, otae029.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Heterologous expression of the human wild-type and variant NaV1.8 (A1073V) in rat sensory neurons
Kapur, M. M., Soliman, M., Blanke, E. N., Herold, P. B., Janicki, P. K., Vrana, K. E., Coates, M. D. & Ruiz-Velasco, V., Mar 2024, In: Neurogastroenterology and Motility. 36, 3, e14748.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Career Citation Milestone Award - D (500) Club
Broach, J. (Recipient), Coates, M. (Recipient), Duffy, C. (Recipient), Gardner, A. (Recipient), Gill, D. (Recipient), Helm, K. (Recipient), Kimball, S. (Recipient), Leslie, D. (Recipient), Lipton, A. (Recipient), Ma, T. (Recipient), Naccarelli, G. (Recipient), Schmitz, K. (Recipient), Siedlecki, C. (Recipient), Stoute, J. (Recipient), Tombran-Tink, J. (Recipient) & Wang, H.-G. (Recipient), 2020
Prize