Projects per year
Personal profile
Research interests
Dr. Matthew Coates is a physician-scientist with long-standing research interest relating to the interplay between inflammatory bowel disease (IBD) and neuroendocrine signaling systems. To this end, he has focused much of his effort evaluating intestinal serotonin, neurotrophic and other signaling systems in the context of IBD and other inflammatory disorders of the gut. He is also very interested in how these factors impact visceral sensation and other key functions of the gastrointestinal tract.
His laboratory utilizes a variety of innovative molecular (e.g., next-generation genomics, immunohistochemistry, immunoassays) and functional (e.g., quantitative sensory and visceromotor testing) techniques to investigate these issues.
Dr. Coates is also overseeing the development of a gastroenterology-based intestinal disease data registry and biorepository. As part of this effort, critical data and tissue samples (including endoscopically derived intestinal biopsies and blood) are collected in order to facilitate multi-modal, prospective studies related to the research interests described above as well as related topics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Gastroenterology, Hepatology and Nutrition, Fellowship, University of Pittsburgh School of Medicine
… → Aug 2013
Internal Medicine, Residency, University of Vermont College of Medicine
… → Jun 2010
MD, University of Vermont College of Medicine
… → May 2007
PhD, University of Vermont College of Medicine
… → May 2005
AB, Princeton University
… → Jun 1996
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Collaborations and top research areas from the last five years
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The Role of the Voltage-Gated Sodium Channel, NaV1.8, in Silent Inflammatory Bowel Disease
National Institute of Diabetes and Digestive and Kidney Diseases
4/10/20 → 1/31/24
Project: Research project
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The Role of Intestinal Mucosal Serotonin Uptake in IBS
National Institute of Neurological Disorders and Stroke
6/29/05 → 6/28/06
Project: Research project
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Abdominal Pain in Inflammatory Bowel Disease: An Evidence-Based, Multidisciplinary Review
Coates, M. D., Clarke, K., Williams, E., Jeganathan, N., Yadav, S., Giampetro, D., Gordin, V., Smith, S., Vrana, K., Bobb, A., Gazzio, T. T., Tressler, H. & Dalessio, S., Oct 1 2023, In: Crohn's and Colitis 360. 5, 4, otad055.Research output: Contribution to journal › Article › peer-review
Open Access -
Abdominal pain is associated with an increased risk of future healthcare resource utilization in inflammatory bowel disease
Zubrzycka, I., Bogale, K., Stuart, A., Cesaire, M., Walter, V., Dalessio, S., Tinsley, A., Williams, E., Clarke, K. & Coates, M. D., Dec 2023, In: International Journal of Colorectal Disease. 38, 1, 213.Research output: Contribution to journal › Article › peer-review
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Improving outpatient care in adult inflammatory bowel disease: Effect of implementation of a reminder checklist in the electronic health records (IBD-ERS) - A pilot study
Bernasko, N., Venkateswaran, N., Coates, M., Dalessio, S., Williams, E. & Clarke, K., Feb 6 2023, In: BMJ Open Quality. 12, 1, e002008.Research output: Contribution to journal › Article › peer-review
Open Access -
Lifestyle Factors Associated with Abdominal Pain in Quiescent Inflammatory Bowel Disease
Coates, M. D., Dalessio, S., Walter, V., Stuart, A., Tinsley, A., Williams, E. D. & Clarke, K., Nov 2023, In: Digestive Diseases and Sciences. 68, 11, p. 4156-4165 10 p.Research output: Contribution to journal › Article › peer-review
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Short-Term and Long-Term Opioid Use Is Associated With Poor Outcomes in Outpatients With Inflammatory Bowel Disease
Telfer, L., Dalessio, S., Tinsley, A. & Coates, M., Jan 2023, In: Gastro Hep Advances. 2, 8, p. 1022-1024 3 p.Research output: Contribution to journal › Short survey › peer-review
Open Access
Prizes
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Career Citation Milestone Award - D (500) Club
Broach, James (Recipient), Coates, Matthew (Recipient), Duffy, Charles (Recipient), Gardner, Andrew (Recipient), Gill, Donald (Recipient), Helm, Klaus (Recipient), Kimball, Scot (Recipient), Leslie, Douglas (Recipient), Lipton, Allan (Recipient), Ma, Thomas (Recipient), Naccarelli, Gerald (Recipient), Schmitz, Kathryn (Recipient), Siedlecki, Christopher (Recipient), Stoute, Jose (Recipient), Tombran-Tink, Joyce (Recipient) & Wang, Hong-Gang (Recipient), 2020
Prize