Personal profile
Research interests
As a veterinary pathologist with a focus in comparative medicine, Dr. Matthew Lanza has collaborated with investigators from many fields of biology and medicine with particular emphasis on rodent models in cancer research. These collaborations include histopathological phenotyping of genetically manipulated mice as well as assessing the toxicity and efficacy of cancer treatments, particularly immunotherapy including chimeric antigen receptor (CAR) T-cell treatments. Other projects have included characterization of immune responses to infectious agents, evaluation of wound healing with synthetic tissue grafts, and refinement of histopathological scoring systems of various diseases.
Professional information
Diplomate, American College of Veterinary Pathologists (DACVP), 2021
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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CK2α Deletion in the Hematopoietic Compartment Shows a Mild Alteration in Terminally Differentiated Cells and the Expansion of Stem Cells
Rajaiah, R., Daniyal, M., Shanmugam, M. P., Valensi, H., Duke, K., Mercer, K., Klink, M., Lanza, M., Uzun, Y., Huang, S., Dovat, S. & Behura, C. G., Jul 2025, In: Cells. 14, 13, 963.Research output: Contribution to journal › Article › peer-review
Open Access -
MyD88-mediated signaling in intestinal fibroblasts regulates macrophage antimicrobial defense and prevents dysbiosis in the gut
Chulkina, M., Tran, H., Uribe, G., McAninch, S. B., McAninch, C., Seideneck, A., He, B., Lanza, M., Khanipov, K., Golovko, G., Powell, D. W., Davenport, E. R. & Pinchuk, I. V., May 27 2025, In: Cell Reports. 44, 5, 115553.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Preliminary Long-Term Biocompatibility Assessment of Penn State University Child Pump
Jhun, C. S., Clark, J. B., Gentile, J. I., Cysyk, J. P., Bohnenberger, K., Scheib, C. M., Izer, J., Lanza, M., Tillinger, M., Flory, H., Yeager, E., Weiss, W. J. & Rosenberg, G., Sep 1 2025, In: ASAIO Journal. 71, 9, p. e126-e129Research output: Contribution to journal › Article › peer-review
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Red blood cells capture and deliver bacterial DNA to drive host responses during polymicrobial sepsis
Lam, L. K. M., Klingensmith, N. J., Sayegh, L., Oatman, E., Jose, J. S., Cosgriff, C. V., Eckart, K. A., McGinnis, J., Ranjan, P., Lanza, M., Yehya, N., Meyer, N. J., Dickson, R. P. & Mangalmurti, N. S., Feb 17 2025, In: Journal of Clinical Investigation. 135, 4, e182127 e182127.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
Short-Term and Long-Term Effects of Electronic Cigarettes on Mouse Lungs Following Nose-Only Exposures
Sinha, I., Bitzer, Z., Barnett, S., Reinhart, L., Umstead, T. M., Chroneos, Z. C., Lanza, M., Sun, D., Zhu, J., Richie, J. P. & Sinha, R., Jun 16 2025, In: Chemical research in toxicology. 38, 6, p. 1019-1036 18 p.Research output: Contribution to journal › Article › peer-review
Prizes
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Dean's Award for Excellence in Teaching
McAlevy, M. (Recipient), Bonavia, A. (Recipient), Malhotra, A. (Recipient), Weller, G. E. (Recipient), Waning, D. (Recipient), Lanza, M. (Recipient), Ken, K. (Recipient), McCarver, S. (Recipient), Glasser, J. (Recipient), Schooler, J. (Recipient), Lewis, S. (Recipient), Onks, C. (Recipient), Rao, R. (Recipient), Nickolich, S. (Recipient), Helm, L. (Recipient), Critchfield, L. (Recipient), Myers, K. (Recipient), Green, M. (Recipient), Songdej, N. (Recipient), Narayana, S. (Recipient), Razjouyan, H. (Recipient), Duca, N. (Recipient), Casas, R. (Recipient), Cooper, J. (Recipient), Wright, R. (Recipient), Karasinski, A. (Recipient), Probolus, J. A. (Recipient), Madara, J. (Recipient), Guck, D. (Recipient), Ingram, D. (Recipient), De Obaldia, A. (Recipient), Hussein, R. (Recipient), McGillen, B. (Recipient), Chapman, T. (Recipient), Munyon, R. (Recipient), Kinard, S. R. (Recipient), Banks, S. (Recipient), Genao, I. (Recipient), McShane, M. (Recipient), Allie, S. R. (Recipient), Silberman, Y. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Grogan, J. (Recipient), Nguyen, J. (Recipient), Donato, H. (Recipient), Fox, E. (Recipient), Gniady, J. (Recipient), Oladipo, O. (Recipient), Abendroth, C. (Recipient), Keefer, L. (Recipient), Massare, B. (Recipient), Undar, A. (Recipient), Mondal, P. (Recipient), Mainali, G. (Recipient), Jhaveri, P. (Recipient), Freiberg, A. (Recipient), Levenson, R. (Recipient), Mailman, R. (Recipient), Boodoo, R. (Recipient), Francis, A. (Recipient), Hameed, U. (Recipient), Yadav, S. (Recipient), Calo, W. (Recipient), Pinto, C. (Recipient), Cooper, A. (Recipient), Kulaylat, A. (Recipient), Scow, J. (Recipient), Roberts, J. (Recipient), Winder, J. (Recipient), Aminsharifi, A. (Recipient), Adams, N. (Recipient) & van Riggelen, J. (Recipient), 2023
Prize
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Dean's Award for Excellence in Teaching
Hussein, R. (Recipient), Stredny, E. (Recipient), Whitley, M. (Recipient), Mnatsakanyan, N. (Recipient), Raimundo, N. (Recipient), Zarnescu, D. (Recipient), Adams, N. (Recipient), Lanza, M. (Recipient), Kowalczyk, A. (Recipient), Travelute, C. (Recipient), Marco, C. (Recipient), Tondt, J. (Recipient), Anderson, A. (Recipient), Heron, C. (Recipient), Newman, R. (Recipient), Richard, D. (Recipient), Scartozzi, C. (Recipient), Dellasega, C. (Recipient), Akhtar, N. (Recipient), Albano-Aluquin, S. (Recipient), Chisty, A. (Recipient), Crook, T. (Recipient), Federici, E. H. (Recipient), Ingram, D. (Recipient), Lakshmanan, P. (Recipient), Mathew, A. (Recipient), Narayana, S. (Recipient), Prokop, A. (Recipient), Razjouyan, H. (Recipient), Tariq, A. (Recipient), Thompson, B. (Recipient), Thompson, E. (Recipient), Trivedi, N. (Recipient), Van Scoy, L. (Recipient), Wong, J. (Recipient), Allie, S. R. (Recipient), Browning, K. (Recipient), Evey, L. (Recipient), McLaughlin, P. (Recipient), Mamarabadi, M. (Recipient), Shankar, L. (Recipient), Bowie, E. (Recipient), Petfield, J. (Recipient), Whitaker, M. (Recipient), Aynardi, J. (Recipient), Allen, N. (Recipient), Cunningham, B. (Recipient), Gandhi, C. (Recipient), Jairath, B. (Recipient), Lutzkanin, K. M. (Recipient), Kerris, E. (Recipient), Nelson, A. (Recipient), Shook, J. (Recipient), Proctor, E. A. (Recipient), Raup-Konsavage, W. (Recipient), Romanoski, N. (Recipient), Graziane, J. (Recipient), Llorente, A. (Recipient), Nutting, S. (Recipient), Pinto, C. (Recipient), Yingst, J. (Recipient), Zhou, S. (Recipient), Mahase, S. (Recipient), Brian, P. (Recipient), Goldman, E. (Recipient), Maffie, J. (Recipient), Brahmbhatt, R. (Recipient), Fahy, A. (Recipient), Gish, J. (Recipient), Reed, M. F. (Recipient) & Tomasko, J. (Recipient), 2024
Prize