Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 9 Finished
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Molecular interactions of histone ubiquitylation enzymes with the nucleosome
Tan, S. (PI)
National Institute of General Medical Sciences
8/1/14 → 7/31/19
Project: Research project
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Structural Basis for RCC1 Directed Recruitment of Ran GTPase to Chromatin
Tan, S. (PI)
National Institute of General Medical Sciences
8/1/09 → 7/31/19
Project: Research project
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Dynamics of Higher Order Chromatin Structure
Bartholomew, B. B. (PI), Tan, S. (CoPI) & Freitas, M. M. A. (CoPI)
9/1/08 → 8/31/11
Project: Research project
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KETJU. Post-Newtonian modelling of the dynamics of supermassive black holes in galactic-scale hydrodynamical simulations (KETJU)
Johansson, P. H. P. H. (PI), Bartholomew, B. B. (PI), Tan, S. (CoPI) & Freitas, M. M. A. (CoPI)
9/1/08 → 9/30/25
Project: Research project
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Promoter Regulation in Response to Environmental Stress
Pugh, F. B. (PI) & Tan, S. (CoPI)
National Institute of Environmental Health Sciences
1/1/07 → 2/29/20
Project: Research project
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Roles of histone chaperone Nap1 and histone acetylation in regulating phase-separation of nucleosome arrays
Gao, J., Li, H., Tan, S., Zhou, R. & Lee, T. H., Dec 2025, In: Nature communications. 16, 1, 10672.Research output: Contribution to journal › Article › peer-review
Open Access -
Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1
Xu, C., Kleinschmidt, H., Yang, J., Leith, E. M., Johnson, J., Tan, S., Mahony, S. & Bai, L., Aug 8 2024, In: Molecular cell. 84, 15, p. 2838-2855.e10Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions
Donovan, B. T., Chen, H., Eek, P., Meng, Z., Jipa, C., Tan, S., Bai, L. & Poirier, M. G., Apr 20 2023, In: Molecular cell. 83, 8, p. 1251-1263.e6Research output: Contribution to journal › Article › peer-review
Open Access30 Link opens in a new tab Scopus citations -
Cryo-EM structure of the human Sirtuin 6–nucleosome complex
Chio, U. S., Rechiche, O., Bryll, A. R., Zhu, J., Leith, E. M., Feldman, J. L., Peterson, C. L., Tan, S. & Armache, J. P., Apr 2023, In: Science Advances. 9, 15, eadf7586.Research output: Contribution to journal › Article › peer-review
Open Access24 Link opens in a new tab Scopus citations -
Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration
Namitz, K. E. W., Tan, S. & Cosgrove, M. S., Feb 2023, In: Journal of Biological Chemistry. 299, 2, 102874.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations