Projects per year
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Collaborations and top research areas from the last five years
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Dynamics of DNA-histone interactions
Lee, T.-H. (PI)
National Institute of General Medical Sciences
8/1/23 → 7/31/25
Project: Research project
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Effects of histone ubiquitylation on nucleosome dynamics
Lee, T.-H. (PI)
National Institute of General Medical Sciences
8/1/19 → 5/31/23
Project: Research project
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Dynamics of histone-DNA interaction
Lee, T.-H. (PI)
National Institute of General Medical Sciences
2/1/18 → 1/31/22
Project: Research project
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Dynamics of nucleosome assembly/disassembly affected by chromatin modifications
Lee, T.-H. (PI)
National Institute of General Medical Sciences
7/1/11 → 6/30/17
Project: Research project
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Dynamics in Translation: the Role of Fluctuation in Protein Synthesis
Lee, T.-H. (PI)
National Institute of General Medical Sciences
7/1/07 → 6/30/10
Project: Research project
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Effects of Histone H2B Ubiquitylations and H3K79me3 on Transcription Elongation
Huynh, M. T., Sengupta, B., Krajewski, W. A. & Lee, T. H., Mar 17 2023, In: ACS chemical biology. 18, 3, p. 537-548 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Histone H3 Tail Modifications Alter Structure and Dynamics of the H1 C-Terminal Domain Within Nucleosomes
Das, S. K., Kumar, A., Hao, F., Cutter DiPiazza, A. R., Fang, H., Lee, T. H. & Hayes, J. J., Oct 1 2023, In: Journal of Molecular Biology. 435, 19, 168242.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Methods to investigate nucleosome structure and dynamics with single-molecule FRET
Das, S. K., Huynh, M. T., Gao, J., Sengupta, B., Yadav, S. P. & Lee, T. H., Jul 2023, In: Methods. 215, p. 17-27 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Spontaneous histone exchange between nucleosomes
Das, S. K., Huynh, M. T. & Lee, T. H., Aug 2023, In: Journal of Biological Chemistry. 299, 8, 105037.Research output: Contribution to journal › Article › peer-review
Open Access -
DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding
Spangler, C. J., Yadav, S. P., Li, D., Geil, C. N., Smith, C. B., Wang, G. G., Lee, T. H. & McGinty, R. K., Feb 15 2022, In: Cell Reports. 38, 7, 110369.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations