Projects per year
Personal profile
Research interests
Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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The role and mechanism of necrosis in glioblastoma
Li, W. (PI)
2/1/21 → 1/31/22
Project: Research project
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THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION
Li, W. (PI)
9/1/18 → 7/31/23
Project: Research project
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The mechanism and function of cell competition in tumors
Li, W. (PI)
8/19/15 → 7/31/18
Project: Research project
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Inhibition of thioredoxin reductase 1 sensitizes glucose-starved glioblastoma cells to disulfidptosis
Tang, M., Dirks, K., Kim, S. Y., Qiu, Z., Gao, Y., Sun, D., Peruggia, G., Sallavanti, J. & Li, W., Apr 2025, In: Cell Death and Differentiation. 32, 4, p. 598-612 15 p., 2700.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Involvement of p38 MAPK and MAPKAPK2 in promoting cell death and the inflammatory response to ischemic stress associated with necrotic glioblastoma
Kim, S. Y., Tang, M., Chih, S. Y., Sallavanti, J., Gao, Y., Qiu, Z., Wang, H. G. & Li, W., Dec 2025, In: Cell Death and Disease. 16, 1, 12.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Neutrophil Engulfment in Cancer: Friend or Foe?
Lu, T. & Li, W., Feb 2025, In: Cancers. 17, 3, 384.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Ferroptosis in glioma therapy: advancements in sensitizing strategies and the complex tumor-promoting roles
Yeon Kim, S., Tang, M., Lu, T., Chih, S. Y. & Li, W., Oct 1 2024, In: Brain research. 1840, 149045.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
LC3-associated phagocytosis of neutrophils triggers tumor ferroptotic cell death in glioblastoma
Lu, T., Yee, P. P., Chih, S. Y., Tang, M., Chen, H., Aregawi, D. G., Glantz, M. J., Zacharia, B. E., Wang, H.-G. & Li, W., Jul 1 2024, In: EMBO Journal. 43, 13, p. 2582-2605 24 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations