Personal profile
Research interests
Dr. Xiaowei Su’s research focuses on amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease). He has a specific interest in machine learning techniques using ALS biomarkers to improve predictions for disease progression and survival. He has participated in multicenter collaborations investigating disease biomarkers to better understand ALS pathophysiology.
He is involved in clinical trials investigating new therapies, remote monitoring and quality of life. He recruits for multicenter clinical trials for new treatments in patients with ALS. He has additional training in patient-centered trial design, operations, and analysis through the Penn State Clinical and Translational Sciences Institute initiative sponsored by the National Institutes of Health.
Dr. Su is also interested in the bioethics of care delivery, clinical trials and medical genetics. This research attempts to ensure equitable access to healthcare as well as the availability of new medical advances to the maximum number of individuals who may benefit.
Clinical interests
Dr. Xiaowei Su treats a broad spectrum of neuromuscular diseases including motor neuron disorders (ALS); muscle diseases (dystrophies, metabolic muscle disorders, and acquired myopathies); neuromuscular junction disorders (myasthenia gravis); and autoimmune peripheral nerve diseases (Guillain-Barre disease and chronic inflammatory demyelinating polyradiculoneuropathy, CIDP).
Dr. Su works in the Penn State Health Hershey Multidisciplinary ALS Clinic with a team of dedicated ALS nurses, psychologists, speech and respiratory therapists, dietitians, physical and occupational therapists, and social workers to care for the complex needs of patients with ALS. Dr. Su also diagnoses neuromuscular diseases using electromyography and nerve conduction studies (EMG/NCS). He provides EMG/NCS services at the Penn State Neuroscience Institute clinic in Hershey and at the Penn State Health Camp Hill Specialties clinic in Camp Hill.
Professional information
Board certification in Electrodiagnostic Medicine, American Board of Electrodiagnostic Medicine (2022)
Board certification in Neuromuscular Medicine, American Board of Psychiatry and Neurology (2022)
Board certification in Neurology, American Board of Psychiatry and Neurology (2020)
Certification in Clinical and Translational Research, Penn State Clinical and Translational Science Institute (2016)
Education/Academic qualification
Neuromuscular medicine, Fellow, Penn State Health Milton S. Hershey Medical Center
2020 → 2021
Neurology, Residency, University of Pittsburgh Medical Center (UPMC)
2016 → 2020
MD, Penn State College of Medicine
2014 → 2016
Molecular medicine, PhD, Penn State University Park
2011 → 2014
Pre-clinical, Penn State College of Medicine
2009 → 2011
Research Assistant, Yale University
2008 → 2009
Biology, BS, Yale University
… → 2008
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial
Authors/Writing Committee for the HEALEY ALS Platform Trial, Apr 1 2025, In: JAMA. 333, 13, p. 1138-1149 12 p.Research output: Contribution to journal › Article › peer-review
9 Link opens in a new tab Scopus citations -
Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial
HEALEY ALS Platform Trial Study Group, Feb 3 2025, In: JAMA network open. 8, 2, p. e2459058 e2459058.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
Pridopidine in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial
Authors/Writing Committee for the HEALEY ALS Platform Trial, Apr 1 2025, In: JAMA. 333, 13, p. 1128-1137 10 p.Research output: Contribution to journal › Article › peer-review
16 Link opens in a new tab Citations (SciVal) -
Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial
Writing Committee for the HEALEY ALS Platform Trial, Apr 1 2025, In: JAMA neurology. 82, 4, p. 333-343 11 p.Research output: Contribution to journal › Article › peer-review
11 Link opens in a new tab Scopus citations -
Lessons from the HEALEY adaptive platform trial in amyotrophic lateral sclerosis
on behalf of the HEALEY ALS Platform Trial Study Group, Nov 2024, In: Nature Aging. 4, 11, p. 1512-1515 4 p.Research output: Contribution to journal › Comment/debate › peer-review
3 Link opens in a new tab Scopus citations