Projects per year
Personal profile
Research interests
Dr. Yasin Uzun uses bioinformatics and genomics methods to understand gene regulation at the molecular level. For this purpose, he employs Systems Biology approaches to utilize next generation sequencing data, with a particular emphasis on single-cell genomics for modeling epigenetic control. His studies in this field reveal the molecular mechanisms that switch the genes on and off during cell differentiation. In this way, he investigates how the dysregulation in these control mechanisms are associated with various genetic diseases with a particular focus on cancer and how this information can present novel therapeutic opportunities.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Yasin Uzun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
-
Integrated frameworks for single-cell epigenomics based transcriptional regulatory networks
Uzun, Y. (PI)
National Institute of General Medical Sciences
9/1/23 → 7/31/26
Project: Research project
-
Analysis of gene regulatory networks from gene expression using graph neural networks
Otal, H. T., Subasi, A., Kurt, F., Canbaz, M. A. & Uzun, Y., Jan 1 2025, Digital Healthcare, Digital Transformation and Citizen Empowerment in Asia-Pacific and Europe for a Healthier Society: Volume 5. Elsevier, Vol. 5. p. 249-270 22 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
CK2α Deletion in the Hematopoietic Compartment Shows a Mild Alteration in Terminally Differentiated Cells and the Expansion of Stem Cells
Rajaiah, R., Daniyal, M., Shanmugam, M. P., Valensi, H., Duke, K., Mercer, K., Klink, M., Lanza, M., Uzun, Y., Huang, S., Dovat, S. & Behura, C. G., Jul 2025, In: Cells. 14, 13, 963.Research output: Contribution to journal › Article › peer-review
Open Access -
Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring
Yu, W., Biyik-Sit, R., Uzun, Y., Chen, C. H., Thadi, A., Sussman, J. H., Pang, M., Wu, C. Y., Grossmann, L. D., Gao, P., Wu, D. W., Yousey, A., Zhang, M., Turn, C. S., Zhang, Z., Bandyopadhyay, S., Huang, J., Patel, T., Chen, C. & Martinez, D. & 6 others, , May 2025, In: Nature Genetics. 57, 5, p. 1142-1154 13 p., 3620.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Noncoding RNA, ncRNA-a3, Epigenetically Regulates TAL1 Transcriptional Program During Erythropoiesis
Matur, M., Uzun, Y., Shi, X., Hamamoto, K., Qiu, Y. & Huang, S., 2025, In: Molecular and cellular biology. 45, 4, p. 169-184 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Advances in computational and experimental approaches for deciphering transcriptional regulatory networks: Understanding the roles of cis-regulatory elements is essential, and recent research utilizing MPRAs, STARR-seq, CRISPR-Cas9, and machine learning has yielded valuable insights
Moeckel, C., Mouratidis, I., Chantzi, N., Uzun, Y. & Georgakopoulos-Soares, I., Jul 2024, In: BioEssays. 46, 7, 2300210.Research output: Contribution to journal › Review article › peer-review
Open Access