Arousal-induced noradrenergic signaling modulates cortical astrocyte-neuron circuits during ethanol consumption

Project: Research project

Project Details


Patients with disorders in arousal, such as post-traumatic stress disorder (PTSD), are particularly susceptible to developing alcohol use disorders (AUD). In this application, I will study the novel role of astrocyte-neuron networks in the prefrontal cortex and their modulation by arousal-induced noradrenergic release while mice actively drink alcohol. These longitudinal studies of the relationship between astrocyte-neuron dynamics and arousal during alcohol consumption will provide important information on arousal disorders, such as PTSD and AUD, and may provide clinical hallmarks or therapeutic avenues for the treatment of these disorders.
Effective start/end date3/14/212/28/23


  • National Institute on Alcohol Abuse and Alcoholism: $184,409.00


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.