Project Details
Description
PROJECT NARRATIVE
JC polyomavirus (JCPyV), a prevalent human-only pathogen, causes life-threatening brain diseases in
immunologically compromised individuals. The list of immunotherapeutic and chemotherapeutic agents linked
to JCPyV CNS diseases is rapidly expanding; no anti-JCPyV agents are available. Using a mouse virus in the
same family as JCPyV, we developed a tractable animal model to explore early stages in the pathogenesis of
polyomavirus brain infections that precede development of irreversible lesions.
| Status | Finished |
|---|---|
| Effective start/end date | 5/1/16 → 1/31/23 |
Funding
- National Institute of Neurological Disorders and Stroke: $336,252.00
- National Institute of Neurological Disorders and Stroke: $430,944.00
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