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Keyphrases
Metabolic Activation
100%
Keap1-Nrf2
100%
Nitroarenes
100%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
78%
AKR1C
65%
DNA Adducts
45%
Nitroreductase
40%
Lung Cancer
38%
Nrf2 Activator
38%
3-Nitrobenzanthrone
32%
Air Pollutants
32%
NsSNPs
25%
AKR1C1
23%
Diesel Exhaust
23%
Kelch-like ECH-associated Protein 1 (Keap1)
22%
Nitroarene Reduction
20%
1-Nitropyrene
20%
Keap1-Nrf2 Pathway
20%
Aldo-keto Reductase
16%
AKR1C3
16%
Air Pollution
16%
A549 Cells
16%
Vicious Circle
12%
Electrophile
12%
Human Lung Adenocarcinoma Cells
12%
UPLCâ„¢
12%
Hypermethylated
12%
Prototypic
12%
Human Bronchial Epithelial
12%
Cancer Initiation
12%
Genotoxicity
12%
Significant Genes
12%
Gene Silencing
12%
DNA Adduct Formation
12%
Gene-environment Interaction
12%
Nrf2 Gene
12%
Normal Human
12%
Reactive Oxygen Species
12%
Environmental Pollutants
12%
Allelic Variants
12%
Transcriptomic Changes
12%
Lung Cancer Screening
12%
In(III)
12%
Regulatory Genes
12%
Stable Isotope Dilution
10%
Human Lung Cells
8%
Cas9 Protein
8%
Genotype
7%
Risk Stratification
7%
Isotope Dilution Liquid Chromatography Tandem Mass Spectrometry (ID-LC-MS/MS)
7%
Ion Trap Mass Spectrometer
7%
Stable Isotopes
5%
Chromatography-mass Spectrometry
5%
Pollutants
5%
Mass Spectrometry
5%
Biochemistry, Genetics and Molecular Biology
Metabolic Activation
100%
Transcription Factor Nrf2
100%
KEAP1
32%
DNA Adduct
32%
Enzyme
28%
Nitroreductase
19%
Reduction (Chemistry)
15%
Carcinogenesis
14%
AKR1C1
13%
Single-Nucleotide Polymorphism
11%
AKR1C3
10%
Genetics
9%
Dilution
8%
Liquid Chromatography-Mass Spectrometry
8%
Aldo-Keto Reductase
8%
CRISPR/Cas9
5%
Gene-Environment Interaction
5%
Normal Human
5%
Promoter Region
5%
Gene Inactivation
5%
Cancer Screening
5%
NADPH-Quinone Oxidoreductase
5%
Upregulation
5%
Transcriptomics
5%