PHARMACOKINETIC STUDY OF TAXOL &CARBOPLATIN WITH FILGRASTIM IN LUNG CARCINOMA

Project: Research project

Project Details

Description

The objective of this phase I/II study is to determine the maximum tolerated dose of taxol in combination with carboplatin in previously untreated patients with advanced or recurrent non-small cell lung cancer (NSCLC); define the pharmacokinetics of carboplatin with combination therapy and correlate 24 hour total plasma platinum concentration and pharmacodynamic consequences of therapy with carboplatin area under the concentration curve.
StatusFinished
Effective start/end date10/1/969/30/97

Funding

  • National Center for Research Resources

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