PHASE I/II PHARMACOKINETIC STUDY OF TAXOL AND CARBOPLATIN WITH FILGRASTIM

Project: Research project

Project Details

Description

The objective of this phase I/II study is to determine the maximum tolerated dose of taxol in combination with carboplatin in previously untreated patients with advanced or recurrent Non Small Cell Lung Cancer (NSCLC); define the pharmacokinetics of carboplatin with combination therapy, and correlate 24 hour total plasma platinum concentration and pharmacodynamic consequences of therapy with the AUC of carboplatin.
StatusFinished
Effective start/end date10/1/959/30/96

Funding

  • National Center for Research Resources

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