Role of lincRNAs in HSC function and leukemogenesis

  • Huang, Suming (CoPI)
  • Xu, Mingjiang (CoPI)
  • Xu, Mingjiang M (PI)
  • Huang, Suming S (CoPI)

Project: Research project

Project Details


Narrative The goal of this project is to understand the role of HOXB locus-associated lncRNA, HOXBLINC, in hematopoietic stem cell regulation and leukemogenesis. Our studies will unveil the mechanisms by which HoxBlinc lncRNA fine-tune HOX gene activation and modulate hematopoietic stem cell behavior. Our project could identify a novel oncogenic lncRNA and therapeutic target for patients with HOX gene dysregulation.
Effective start/end date1/15/1912/31/22


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