Project Details
Description
Narrative
The goal of this project is to understand the role of HOXB locus-associated lncRNA, HOXBLINC, in
hematopoietic stem cell regulation and leukemogenesis. Our studies will unveil the mechanisms by which
HoxBlinc lncRNA fine-tune HOX gene activation and modulate hematopoietic stem cell behavior. Our project
could identify a novel oncogenic lncRNA and therapeutic target for patients with HOX gene dysregulation.
Status | Finished |
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Effective start/end date | 1/15/19 → 12/31/22 |
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