β-adrenergic involvement in acquisition vs. extinction of a classically conditioned eye blink response in rabbits

Thomas J. Gould

doi:10.1016/S0006-8993(97)01305-X

β-adrenergic involvement in acquisition vs. extinction of a classically conditioned eye blink response in rabbits

Thomas J. Gould

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

β-adrenergic involvement in classical conditioning and extinction was investigated. Five groups of rabbits (saline, 1, 3, 5 or 10 mg kg^-1 of the β-adrenergic antagonist propranolol) were trained with a tone conditioned stimulus (CS) paired with a corneal air puff unconditioned stimulus (US). Both 5 mg kg^-1 and 10 mg kg^-1 propranolol delayed acquisition of conditioned responses but all groups were able to learn the task to criterion. Consistent changes were not seen during extinction.

Original language	English (US)
Pages (from-to)	174-177
Number of pages	4
Journal	Brain research
Volume	780
Issue number	1
DOIs	https://doi.org/10.1016/S0006-8993(97)01305-X
State	Published - Jan 5 1998

All Science Journal Classification (ASJC) codes

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(97)01305-X

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abstract = "β-adrenergic involvement in classical conditioning and extinction was investigated. Five groups of rabbits (saline, 1, 3, 5 or 10 mg kg-1 of the β-adrenergic antagonist propranolol) were trained with a tone conditioned stimulus (CS) paired with a corneal air puff unconditioned stimulus (US). Both 5 mg kg-1 and 10 mg kg-1 propranolol delayed acquisition of conditioned responses but all groups were able to learn the task to criterion. Consistent changes were not seen during extinction.",

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AB - β-adrenergic involvement in classical conditioning and extinction was investigated. Five groups of rabbits (saline, 1, 3, 5 or 10 mg kg-1 of the β-adrenergic antagonist propranolol) were trained with a tone conditioned stimulus (CS) paired with a corneal air puff unconditioned stimulus (US). Both 5 mg kg-1 and 10 mg kg-1 propranolol delayed acquisition of conditioned responses but all groups were able to learn the task to criterion. Consistent changes were not seen during extinction.

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β-adrenergic involvement in acquisition vs. extinction of a classically conditioned eye blink response in rabbits

Abstract

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