β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines

Steven M. Weinreb; Donald M. Demko; Thomas A. Lessen; James P. Demers

doi:10.1016/S0040-4039(00)84458-5

β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines

Steven M. Weinreb
, Donald M. Demko
, Thomas A. Lessen
, James P. Demers

Chemistry

Research output: Contribution to journal › Article › peer-review

167 Scopus citations

Abstract

The title compound, easily prepared in two steps from vinyltrimethylsilane, is a useful reagent for the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion.

Original language	English (US)
Pages (from-to)	2099-2102
Number of pages	4
Journal	Tetrahedron Letters
Volume	27
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(00)84458-5
State	Published - 1986

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)84458-5

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@article{8dcaecab374645abb450333c5c84cfab,

title = "β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines",

abstract = "The title compound, easily prepared in two steps from vinyltrimethylsilane, is a useful reagent for the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion.",

author = "Weinreb, \{Steven M.\} and Demko, \{Donald M.\} and Lessen, \{Thomas A.\} and Demers, \{James P.\}",

year = "1986",

doi = "10.1016/S0040-4039(00)84458-5",

language = "English (US)",

volume = "27",

pages = "2099--2102",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "19",

}

TY - JOUR

T1 - β-Trimethylsilylethanesulfonyl chloride (SES-Cl)

T2 - A new reagent for protection of amines

AU - Weinreb, Steven M.

AU - Demko, Donald M.

AU - Lessen, Thomas A.

AU - Demers, James P.

PY - 1986

Y1 - 1986

N2 - The title compound, easily prepared in two steps from vinyltrimethylsilane, is a useful reagent for the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion.

AB - The title compound, easily prepared in two steps from vinyltrimethylsilane, is a useful reagent for the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion.

UR - https://www.scopus.com/pages/publications/0000120488

UR - https://www.scopus.com/pages/publications/0000120488#tab=citedBy

U2 - 10.1016/S0040-4039(00)84458-5

DO - 10.1016/S0040-4039(00)84458-5

M3 - Article

AN - SCOPUS:0000120488

SN - 0040-4039

VL - 27

SP - 2099

EP - 2102

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 19

ER -

β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines

Abstract

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