TY - JOUR
T1 - 3D Near-Field Electrospinning of Biomaterial Microfibers with Potential for Blended Microfiber-Cell-Loaded Gel Composite Structures
AU - Fattahi, Pouria
AU - Dover, Jordan T.
AU - Brown, Justin L.
N1 - Funding Information:
The authors thank Brittany L. Banik for critical reading of the manuscript and Daniel T. Bowers for his valuable insights. The authors would also like to thank Dr. Tim Tighe for his help on operating AFM instrument. The authors acknowledge funding from the U.S. National Institutes of Health (NIH) grants AR065192 and EB019230.
Publisher Copyright:
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2017/10/11
Y1 - 2017/10/11
N2 - This paper describes the development of a novel low-cost and efficient method, 3D near-field electrospinning, to fabricate high-resolution, and repeatable 3D polymeric fiber patterns on nonconductive materials with potential use in tissue engineering. This technology is based on readily available hobbyist grade 3D printers. The result is exquisite control of the deposition of single fibers in an automated manner. Additionally, the fabrication of various fiber patterns, which are subsequently translated to unique cellular patterns, is demonstrated. Finally, poly(methyl methacrylate) fibers are printed within 3D collagen gels loaded with cells to introduce anisotropic properties of polymeric fibers within the cell-loaded gels.
AB - This paper describes the development of a novel low-cost and efficient method, 3D near-field electrospinning, to fabricate high-resolution, and repeatable 3D polymeric fiber patterns on nonconductive materials with potential use in tissue engineering. This technology is based on readily available hobbyist grade 3D printers. The result is exquisite control of the deposition of single fibers in an automated manner. Additionally, the fabrication of various fiber patterns, which are subsequently translated to unique cellular patterns, is demonstrated. Finally, poly(methyl methacrylate) fibers are printed within 3D collagen gels loaded with cells to introduce anisotropic properties of polymeric fibers within the cell-loaded gels.
UR - http://www.scopus.com/inward/record.url?scp=85021395947&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021395947&partnerID=8YFLogxK
U2 - 10.1002/adhm.201700456
DO - 10.1002/adhm.201700456
M3 - Article
C2 - 28661043
AN - SCOPUS:85021395947
SN - 2192-2640
VL - 6
JO - Advanced Healthcare Materials
JF - Advanced Healthcare Materials
IS - 19
M1 - 1700456
ER -