6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

James R. Henry; Kenneth C. Rupert; John H. Dodd; Ignatius J. Turchi; Scott A. Wadsworth; Druie E. Cavender; Bohumila Fahmy; Gilbert C. Olini; Janet E. Davis; J. Lee Pellegrino-Gensey; Peter H. Schafer; John J. Siekierka

doi:10.1021/jm980497b

6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

James R. Henry, Kenneth C. Rupert, John H. Dodd, Ignatius J. Turchi, Scott A. Wadsworth, Druie E. Cavender, Bohumila Fahmy, Gilbert C. Olini, Janet E. Davis, J. Lee Pellegrino-Gensey, Peter H. Schafer, John J. Siekierka

Chemistry

Research output: Contribution to journal › Letter › peer-review

79 Scopus citations

Original language	English (US)
Pages (from-to)	4196-4198
Number of pages	3
Journal	Journal of Medicinal Chemistry
Volume	41
Issue number	22
DOIs	https://doi.org/10.1021/jm980497b
State	Published - Oct 23 1998

All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery

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10.1021/jm980497b

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Henry, J. R., Rupert, K. C., Dodd, J. H., Turchi, I. J., Wadsworth, S. A., Cavender, D. E., Fahmy, B., Olini, G. C., Davis, J. E., Lee Pellegrino-Gensey, J., Schafer, P. H., & Siekierka, J. J. (1998). 6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]. Journal of Medicinal Chemistry, 41(22), 4196-4198. https://doi.org/10.1021/jm980497b

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title = "6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]",

author = "Henry, {James R.} and Rupert, {Kenneth C.} and Dodd, {John H.} and Turchi, {Ignatius J.} and Wadsworth, {Scott A.} and Cavender, {Druie E.} and Bohumila Fahmy and Olini, {Gilbert C.} and Davis, {Janet E.} and {Lee Pellegrino-Gensey}, J. and Schafer, {Peter H.} and Siekierka, {John J.}",

year = "1998",

month = oct,

day = "23",

doi = "10.1021/jm980497b",

language = "English (US)",

volume = "41",

pages = "4196--4198",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

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Henry, JR, Rupert, KC, Dodd, JH, Turchi, IJ, Wadsworth, SA, Cavender, DE, Fahmy, B, Olini, GC, Davis, JE, Lee Pellegrino-Gensey, J, Schafer, PH & Siekierka, JJ 1998, '6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]', Journal of Medicinal Chemistry, vol. 41, no. 22, pp. 4196-4198. https://doi.org/10.1021/jm980497b

TY - JOUR

T1 - 6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354)

T2 - A potent and selective p38 kinase inhibitor [4]

AU - Henry, James R.

AU - Rupert, Kenneth C.

AU - Dodd, John H.

AU - Turchi, Ignatius J.

AU - Wadsworth, Scott A.

AU - Cavender, Druie E.

AU - Fahmy, Bohumila

AU - Olini, Gilbert C.

AU - Davis, Janet E.

AU - Lee Pellegrino-Gensey, J.

AU - Schafer, Peter H.

AU - Siekierka, John J.

PY - 1998/10/23

Y1 - 1998/10/23

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U2 - 10.1021/jm980497b

DO - 10.1021/jm980497b

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C2 - 9784093

AN - SCOPUS:7844222102

SN - 0022-2623

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EP - 4198

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 22

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6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

All Science Journal Classification (ASJC) codes

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