6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

James R. Henry; Kenneth C. Rupert; John H. Dodd; Ignatius J. Turchi; Scott A. Wadsworth; Druie E. Cavender; Bohumila Fahmy; Gilbert C. Olini; Janet E. Davis; J. Lee Pellegrino-Gensey; Peter H. Schafer; John J. Siekierka

doi:10.1021/jm980497b

6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

James R. Henry, Kenneth C. Rupert, John H. Dodd, Ignatius J. Turchi, Scott A. Wadsworth, Druie E. Cavender, Bohumila Fahmy, Gilbert C. Olini, Janet E. Davis, J. Lee Pellegrino-Gensey, Peter H. Schafer, John J. Siekierka

Chemistry

Research output: Contribution to journal › Letter › peer-review

79 Scopus citations

Original language	English (US)
Pages (from-to)	4196-4198
Number of pages	3
Journal	Journal of Medicinal Chemistry
Volume	41
Issue number	22
DOIs	https://doi.org/10.1021/jm980497b
State	Published - Oct 23 1998

All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery

Access to Document

10.1021/jm980497b

Cite this

Henry, J. R., Rupert, K. C., Dodd, J. H., Turchi, I. J., Wadsworth, S. A., Cavender, D. E., Fahmy, B., Olini, G. C., Davis, J. E., Lee Pellegrino-Gensey, J., Schafer, P. H., & Siekierka, J. J. (1998). 6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]. Journal of Medicinal Chemistry, 41(22), 4196-4198. https://doi.org/10.1021/jm980497b

@article{a6ee5a616326468c8605ecf5bed1ab3c,

title = "6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]",

author = "Henry, \{James R.\} and Rupert, \{Kenneth C.\} and Dodd, \{John H.\} and Turchi, \{Ignatius J.\} and Wadsworth, \{Scott A.\} and Cavender, \{Druie E.\} and Bohumila Fahmy and Olini, \{Gilbert C.\} and Davis, \{Janet E.\} and \{Lee Pellegrino-Gensey\}, J. and Schafer, \{Peter H.\} and Siekierka, \{John J.\}",

year = "1998",

month = oct,

day = "23",

doi = "10.1021/jm980497b",

language = "English (US)",

volume = "41",

pages = "4196--4198",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "22",

}

Henry, JR, Rupert, KC, Dodd, JH, Turchi, IJ, Wadsworth, SA, Cavender, DE, Fahmy, B, Olini, GC, Davis, JE, Lee Pellegrino-Gensey, J, Schafer, PH & Siekierka, JJ 1998, '6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]', Journal of Medicinal Chemistry, vol. 41, no. 22, pp. 4196-4198. https://doi.org/10.1021/jm980497b

TY - JOUR

T1 - 6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354)

T2 - A potent and selective p38 kinase inhibitor [4]

AU - Henry, James R.

AU - Rupert, Kenneth C.

AU - Dodd, John H.

AU - Turchi, Ignatius J.

AU - Wadsworth, Scott A.

AU - Cavender, Druie E.

AU - Fahmy, Bohumila

AU - Olini, Gilbert C.

AU - Davis, Janet E.

AU - Lee Pellegrino-Gensey, J.

AU - Schafer, Peter H.

AU - Siekierka, John J.

PY - 1998/10/23

Y1 - 1998/10/23

UR - https://www.scopus.com/pages/publications/7844222102

UR - https://www.scopus.com/inward/citedby.url?scp=7844222102&partnerID=8YFLogxK

U2 - 10.1021/jm980497b

DO - 10.1021/jm980497b

M3 - Letter

C2 - 9784093

AN - SCOPUS:7844222102

SN - 0022-2623

VL - 41

SP - 4196

EP - 4198

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 22

ER -

6-amino-2-(4-fluorophenyl)-4-methoxy-3-(4-pyridyl)-1H-pyrrolo[2,3- b]pyridine (RWJ 68354): A potent and selective p38 kinase inhibitor [4]

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Cite this