A cascade cyclization approach to schweinfurthin B

Edward M. Treadwell; Jeffrey Neighbors; David F. Wiemer

doi:10.1021/ol0266368

A cascade cyclization approach to schweinfurthin B

Edward M. Treadwell
, Jeffrey Neighbors
, David F. Wiemer

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

(graph presented) A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phenylselenide substituent for an equatorial orientation.

Original language	English (US)
Pages (from-to)	3639-3642
Number of pages	4
Journal	Organic Letters
Volume	4
Issue number	21
DOIs	https://doi.org/10.1021/ol0266368
State	Published - Oct 17 2002

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol0266368

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title = "A cascade cyclization approach to schweinfurthin B",

abstract = "(graph presented) A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phenylselenide substituent for an equatorial orientation.",

author = "Treadwell, \{Edward M.\} and Jeffrey Neighbors and Wiemer, \{David F.\}",

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T1 - A cascade cyclization approach to schweinfurthin B

AU - Treadwell, Edward M.

AU - Neighbors, Jeffrey

AU - Wiemer, David F.

PY - 2002/10/17

Y1 - 2002/10/17

N2 - (graph presented) A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phenylselenide substituent for an equatorial orientation.

AB - (graph presented) A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phenylselenide substituent for an equatorial orientation.

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AN - SCOPUS:0037126243

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SP - 3639

EP - 3642

JO - Organic Letters

JF - Organic Letters

IS - 21

ER -

A cascade cyclization approach to schweinfurthin B

Abstract

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