TY - JOUR
T1 - A comparison of the major surfactant-associated proteins in different species
AU - Phelps, David
AU - Taeusch, H. William
PY - 1985
Y1 - 1985
N2 - 1. 1. We examined the major surfactant-associated proteins in a number of species by using two-dimensional gel electrophoresis, protein blotting and immunostaining. 2. 2. All species have a 30,000 to 35,000 mol. wt protein group consisting of multiple isoforms with isoelectric points ranging from pH 4.4 to 5.6. 3. 3. The techniques used in this study have resolved three component subgroups within the 35 K group. 4. 4. A group of proteins at 60,000-65,000 mol. wt has also been consistently identified. 5. 5. We conclude that remarkable similarity exists among the major surfactant-associated proteins from various mammals with regard to isoelectric points, molecular weights and antigenic sites.
AB - 1. 1. We examined the major surfactant-associated proteins in a number of species by using two-dimensional gel electrophoresis, protein blotting and immunostaining. 2. 2. All species have a 30,000 to 35,000 mol. wt protein group consisting of multiple isoforms with isoelectric points ranging from pH 4.4 to 5.6. 3. 3. The techniques used in this study have resolved three component subgroups within the 35 K group. 4. 4. A group of proteins at 60,000-65,000 mol. wt has also been consistently identified. 5. 5. We conclude that remarkable similarity exists among the major surfactant-associated proteins from various mammals with regard to isoelectric points, molecular weights and antigenic sites.
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U2 - 10.1016/0305-0491(85)90006-9
DO - 10.1016/0305-0491(85)90006-9
M3 - Article
C2 - 3841307
AN - SCOPUS:0022327720
SN - 0305-0491
VL - 82
SP - 441
EP - 446
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
IS - 3
ER -