A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature

Yiu Keung Lau; Manpreet K. Chadha; Alan Litwin; Donald L. Trump

doi:10.1186/1756-8722-1-21

A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature

Yiu Keung Lau, Manpreet K. Chadha, Alan Litwin, Donald L. Trump

Department of Radiology

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.

Original language	English (US)
Article number	21
Journal	Journal of Hematology and Oncology
Volume	1
Issue number	1
DOIs	https://doi.org/10.1186/1756-8722-1-21
State	Published - 2008

All Science Journal Classification (ASJC) codes

Hematology
Molecular Biology
Oncology
Cancer Research

Access to Document

10.1186/1756-8722-1-21

Cite this

@article{3273d7a4e4cc44e0b8627d3d55c7a317,

title = "A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature",

abstract = "Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.",

author = "Lau, \{Yiu Keung\} and Chadha, \{Manpreet K.\} and Alan Litwin and Trump, \{Donald L.\}",

year = "2008",

doi = "10.1186/1756-8722-1-21",

language = "English (US)",

volume = "1",

journal = "Journal of Hematology and Oncology",

issn = "1756-8722",

publisher = "BioMed Central Ltd.",

number = "1",

}

TY - JOUR

T1 - A dramatic, objective antiandrogen withdrawal response

T2 - Case report and review of the literature

AU - Lau, Yiu Keung

AU - Chadha, Manpreet K.

AU - Litwin, Alan

AU - Trump, Donald L.

PY - 2008

Y1 - 2008

N2 - Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.

AB - Antiandrogen withdrawal response is an increasingly recognized entity in patients with metastatic prostate cancer. To our knowledge, there have been no reports describing a durable radiologic improvement along with prostate-specific antigen (PSA) with discontinuation of the antiandrogen agent bicalutamide. We report a case in which a dramatic decline of serum PSA levels associated with a dramatic improvement in radiologic disease was achieved with bicalutamide discontinuation.

UR - https://www.scopus.com/pages/publications/77953051240

UR - https://www.scopus.com/inward/citedby.url?scp=77953051240&partnerID=8YFLogxK

U2 - 10.1186/1756-8722-1-21

DO - 10.1186/1756-8722-1-21

M3 - Review article

C2 - 18986533

AN - SCOPUS:77953051240

SN - 1756-8722

VL - 1

JO - Journal of Hematology and Oncology

JF - Journal of Hematology and Oncology

IS - 1

M1 - 21

ER -

A dramatic, objective antiandrogen withdrawal response: Case report and review of the literature

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this