A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria

Jordan E. Bisanz, Paola Soto-Perez, Cecilia Noecker, Alexander A. Aksenov, Kathy N. Lam, Grace E. Kenney, Elizabeth N. Bess, Henry J. Haiser, Than S. Kyaw, Feiqiao B. Yu, Vayu M. Rekdal, Connie W.Y. Ha, Suzanne Devkota, Emily P. Balskus, Pieter C. Dorrestein, Emma Allen-Vercoe, Peter J. Turnbaugh

Research output: Contribution to journalArticlepeer-review

29 Citations (SciVal)

Abstract

Bisanz et al. focus on an in-depth study of Eggerthella lenta and the Coriobacteriia class: highly prevalent members of the human gut microbiota which have been poorly described. Through construction of a paired isolate and genome library, they validate tools for comparative genomic approaches to uncover effectors of xenobiotic metabolism and fitness.

Original languageEnglish (US)
Pages (from-to)1001-1013.e9
JournalCell Host and Microbe
Volume27
Issue number6
DOIs
StatePublished - Jun 10 2020

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Virology

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