A growth factor from spinal cord

Thomas Jennings; R. David Jones; Allan Lipton

doi:10.1002/jcp.1041000208

A growth factor from spinal cord

Thomas Jennings, R. David Jones, Allan Lipton

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Mitogenic activity is present at a variety of sites in the central nervous system. A growth factor was purified from neonatal bovine spinal cord. It has a pI of 9.5‐9.8 and a molecular weight of about 11,000 daltons. Spinal cord growth factor is a basic polypeptide that is inactivated by extremely acid or basic conditions. Its mobility on SDS polyacrylamide gels suggests that this factor is different from pituitary FGF and brain FGF‐1.

Original language	English (US)
Pages (from-to)	273-277
Number of pages	5
Journal	Journal of Cellular Physiology
Volume	100
Issue number	2
DOIs	https://doi.org/10.1002/jcp.1041000208
State	Published - Aug 1979

All Science Journal Classification (ASJC) codes

Physiology
Clinical Biochemistry
Cell Biology

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10.1002/jcp.1041000208

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title = "A growth factor from spinal cord",

abstract = "Mitogenic activity is present at a variety of sites in the central nervous system. A growth factor was purified from neonatal bovine spinal cord. It has a pI of 9.5‐9.8 and a molecular weight of about 11,000 daltons. Spinal cord growth factor is a basic polypeptide that is inactivated by extremely acid or basic conditions. Its mobility on SDS polyacrylamide gels suggests that this factor is different from pituitary FGF and brain FGF‐1.",

author = "Thomas Jennings and Jones, {R. David} and Allan Lipton",

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AB - Mitogenic activity is present at a variety of sites in the central nervous system. A growth factor was purified from neonatal bovine spinal cord. It has a pI of 9.5‐9.8 and a molecular weight of about 11,000 daltons. Spinal cord growth factor is a basic polypeptide that is inactivated by extremely acid or basic conditions. Its mobility on SDS polyacrylamide gels suggests that this factor is different from pituitary FGF and brain FGF‐1.

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A growth factor from spinal cord

Abstract

All Science Journal Classification (ASJC) codes

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