Abstract
A monoclonal antibody, HPC-1, labels only amacrine and displaced amacrine cells in adult rat retina. Reactivity with displaced amacrine cells was demonstrated by double-label immunofluorescence with HPC-1 and ganglion cell-specific reagents. HPC-1 antibody reacts with a polypeptide of apparent molecular weight 35,000. HPC-1 antibody labels migrating amacrine cells in late embryonic retinas. The results define cell-specific gene expression in relation to migration of one subclass of CNS neurons.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 286-290 |
| Number of pages | 5 |
| Journal | Brain research |
| Volume | 352 |
| Issue number | 2 |
| State | Published - Jun 1985 |
All Science Journal Classification (ASJC) codes
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology